Genetic depletion indicates a late role for U5 snRNP during in vitro spliceosome assembly.
about
Prp8 protein: at the heart of the spliceosomeThe spliceosome assembly pathway in mammalian extractsA U5 small nuclear ribonucleoprotein particle protein involved only in the second step of pre-mRNA splicing in Saccharomyces cerevisiae.Prp31p promotes the association of the U4/U6 x U5 tri-snRNP with prespliceosomes to form spliceosomes in Saccharomyces cerevisiae.Progression through the spliceosome cycle requires Prp38p function for U4/U6 snRNA dissociationThe biochemical defects of prp4-1 and prp6-1 yeast splicing mutants reveal that the PRP6 protein is required for the accumulation of the [U4/U6.U5] tri-snRNP.Alternative 3'-end processing of U5 snRNA by RNase III.Arrested yeast splicing complexes indicate stepwise snRNP recruitment during in vivo spliceosome assemblyConvergent transcripts of the yeast PRP38-SMD1 locus encode two essential splicing factors, including the D1 core polypeptide of small nuclear ribonucleoprotein particlesThe yeast BDF1 gene encodes a transcription factor involved in the expression of a broad class of genes including snRNAs.Formation of mRNA 3' ends in eukaryotes: mechanism, regulation, and interrelationships with other steps in mRNA synthesisThe Sm complex is required for the processing of non-coding RNAs by the exosomeThree novel functional variants of human U5 small nuclear RNAFunctional analysis of the U5 snRNA loop 1 in the second catalytic step of yeast pre-mRNA splicing.Depletion of yeast RNase III blocks correct U2 3' end formation and results in polyadenylated but functional U2 snRNA.The PRP31 gene encodes a novel protein required for pre-mRNA splicing in Saccharomyces cerevisiae.Requirements for U2 snRNP addition to yeast pre-mRNA.An ATP-independent U2 small nuclear ribonucleoprotein particle/precursor mRNA complex requires both splice sites and the polypyrimidine tract.Sad1 counteracts Brr2-mediated dissociation of U4/U6.U5 in tri-snRNP homeostasis.Antisense oligonucleotide binding to U5 snRNP induces a conformational change that exposes the conserved loop of U5 snRNA.U1 snRNA is cleaved by RNase III and processed through an Sm site-dependent pathwayA yeast splicing factor is localized in discrete subnuclear domains.Reconstitution of functional mammalian U4 small nuclear ribonucleoprotein: Sm protein binding is not essential for splicing in vitro.Roles of U4 and U6 snRNAs in the assembly of splicing complexes.Reconstituted mammalian U4/U6 snRNP complements splicing: a mutational analysis.Roles of PRP8 protein in the assembly of splicing complexes.Construction of an in vivo-regulated U6 snRNA transcription unit as a tool to study U6 function.Synthetic lethal mutations suggest interactions between U5 small nuclear RNA and four proteins required for the second step of splicing
P2860
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P2860
Genetic depletion indicates a late role for U5 snRNP during in vitro spliceosome assembly.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
Genetic depletion indicates a ...... in vitro spliceosome assembly.
@ast
Genetic depletion indicates a ...... in vitro spliceosome assembly.
@en
type
label
Genetic depletion indicates a ...... in vitro spliceosome assembly.
@ast
Genetic depletion indicates a ...... in vitro spliceosome assembly.
@en
prefLabel
Genetic depletion indicates a ...... in vitro spliceosome assembly.
@ast
Genetic depletion indicates a ...... in vitro spliceosome assembly.
@en
P2093
P2860
P356
P1476
Genetic depletion indicates a ...... in vitro spliceosome assembly.
@en
P2093
P2860
P304
P356
10.1093/NAR/19.14.3857
P407
P577
1991-07-01T00:00:00Z