Hipk2 cooperates with p53 to suppress γ-ray radiation-induced mouse thymic lymphoma
about
Role of HIPK2 in kidney fibrosisHIPK2 is a new drug target for anti-fibrosis therapy in kidney diseaseIdentification of Hipk2 as an essential regulator of white fat development.Verbascoside promotes apoptosis by regulating HIPK2-p53 signaling in human colorectal cancerHIPK2 deficiency causes chromosomal instability by cytokinesis failure and increases tumorigenicityUpdates on HIPK2: a resourceful oncosuppressor for clearing cancerTargeting COX-2/PGE(2) pathway in HIPK2 knockdown cancer cells: impact on dendritic cell maturation.Apoptosis induced by a HIPK2 full-length-specific siRNA is due to off-target effects rather than prevalence of HIPK2-Δe8 isoform.HIPK2 restricts SIRT1 activity upon severe DNA damage by a phosphorylation-controlled mechanismGlucose restriction induces cell death in parental but not in homeodomain-interacting protein kinase 2-depleted RKO colon cancer cells: molecular mechanisms and implications for tumor therapyAutophosphorylation and Pin1 binding coordinate DNA damage-induced HIPK2 activation and cell death.Response of mouse thymic cells to radiation after transfusion of mesenchymal stem cells.Homeodomain-interacting protein kinase 2 (HIPK2): a promising target for anti-cancer therapies.ShaPINg Cell Fate Upon DNA Damage: Role of Pin1 Isomerase in DNA Damage-Induced Cell Death and Repair.The Cell-Cycle Arrest and Apoptotic Functions of p53 in Tumor Initiation and Progression.HIPK2 kinase activity depends on cis-autophosphorylation of its activation loop.Src kinase modulates the apoptotic p53 pathway by altering HIPK2 localization.HIPK2 catalytic activity and subcellular localization are regulated by activation-loop Y354 autophosphorylation.The Trp53 delta proline (Trp53ΔP) mouse exhibits increased genome instability and susceptibility to radiation-induced, but not spontaneous, tumor developmentTumor suppressive role for kinases phosphorylating p53 in DNA damage-induced apoptosis
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P2860
Hipk2 cooperates with p53 to suppress γ-ray radiation-induced mouse thymic lymphoma
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Hipk2 cooperates with p53 to suppress γ-ray radiation-induced mouse thymic lymphoma
@ast
Hipk2 cooperates with p53 to suppress γ-ray radiation-induced mouse thymic lymphoma
@en
type
label
Hipk2 cooperates with p53 to suppress γ-ray radiation-induced mouse thymic lymphoma
@ast
Hipk2 cooperates with p53 to suppress γ-ray radiation-induced mouse thymic lymphoma
@en
prefLabel
Hipk2 cooperates with p53 to suppress γ-ray radiation-induced mouse thymic lymphoma
@ast
Hipk2 cooperates with p53 to suppress γ-ray radiation-induced mouse thymic lymphoma
@en
P2093
P2860
P356
P1433
P1476
Hipk2 cooperates with p53 to suppress γ-ray radiation-induced mouse thymic lymphoma
@en
P2093
F G Pelorosso
R DelRosario
P2860
P2888
P304
P356
10.1038/ONC.2011.306
P407
P577
2011-07-25T00:00:00Z