Mu-opioid receptor desensitization: is morphine different?
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Sustained-release oral morphine versus transdermal fentanyl and oral methadone in cancer pain managementCo-activation of μ- and δ-opioid receptors elicits tolerance to morphine-induced ventilatory depression via generation of peroxynitriteLow-dose morphine elicits ventilatory excitant and depressant responses in conscious rats: Role of peripheral μ-opioid receptorsMuscarinic acetylcholine receptor modulation of mu (mu) opioid receptors in adult rat sphenopalatine ganglion neurons.Mu-opioid receptor redistribution in the locus coeruleus upon precipitation of withdrawal in opiate-dependent ratsEndothelin-A receptor antagonism attenuates carcinoma-induced pain through opioids in mice.Loss of morphine reward and dependence in mice lacking G protein-coupled receptor kinase 5.μ-opioid receptors: correlation of agonist efficacy for signalling with ability to activate internalization.Tolerance to the antinociceptive effect of morphine in the absence of short-term presynaptic desensitization in rat periaqueductal gray neuronsAn opioid agonist that does not induce mu-opioid receptor--arrestin interactions or receptor internalization.Agonist-selective mechanisms of GPCR desensitizationOpioid receptor desensitization: mechanisms and its link to toleranceCellular signalling of non-synonymous single-nucleotide polymorphisms of the human μ-opioid receptor (OPRM1)Change in functional selectivity of morphine with the development of antinociceptive tolerance.Does PKC activation increase the homologous desensitization of μ opioid receptors?Opioid tolerance in periaqueductal gray neurons isolated from mice chronically treated with morphine.Differential activation and trafficking of micro-opioid receptors in brain slices.Pharmacological consequence of the A118G μ opioid receptor polymorphism on morphine- and fentanyl-mediated modulation of Ca²⁺ channels in humanized mouse sensory neurons.A6V polymorphism of the human μ-opioid receptor decreases signalling of morphine and endogenous opioids in vitro.Association of OPRM1 A118G variant with risk of morphine-induced respiratory depression following spine fusion in adolescents.Time course of altered sensitivity to inhibitory and excitatory agonist responses in the longitudinal muscle-myenteric plexus and analgesia in the Guinea pig after chronic morphine treatment.The role of β-arrestin2 in the mechanism of morphine tolerance in the mouse and guinea pig gastrointestinal tract.Role of G Protein-Coupled Receptor Kinases 2 and 3 in μ-Opioid Receptor Desensitization and InternalizationEffects of chronic opioid exposure on guinea pig mu opioid receptor in Chinese hamster ovary cells: comparison with human and rat receptorMechanisms of rapid opioid receptor desensitization, resensitization and tolerance in brain neurons.The absence of endogenous beta-endorphin selectively blocks phosphorylation and desensitization of mu opioid receptors following partial sciatic nerve ligation.Mu opioid receptor regulation and opiate responsiveness.Regulation of μ-opioid receptors: desensitization, phosphorylation, internalization, and tolerance.Cellular neuroadaptations to chronic opioids: tolerance, withdrawal and addiction.Quantitative encoding of the effect of a partial agonist on individual opioid receptors by multisite phosphorylation and threshold detection.Agonist-specific regulation of mu-opioid receptor desensitization and recovery from desensitizationMorphine-induced mu-opioid receptor rapid desensitization is independent of receptor phosphorylation and beta-arrestinsIncreased agonist affinity at the μ-opioid receptor induced by prolonged agonist exposure.Morphine: a protective or destructive role in neurons?Persistent inflammatory pain decreases the antinociceptive effects of the mu opioid receptor agonist DAMGO in the locus coeruleus of male rats.Real-time characterization of cannabinoid receptor 1 (CB1 ) allosteric modulators reveals novel mechanism of action.T394A Mutation at the μ Opioid Receptor Blocks Opioid Tolerance and Increases Vulnerability to Heroin Self-Administration in Mice.Multifactorial Regulation of G Protein-Coupled Receptor Endocytosis.Role of protein kinase C in functional selectivity for desensitization at the mu-opioid receptor: from pharmacological curiosity to therapeutic potential.Morphine-induced trafficking of a mu-opioid receptor interacting protein in rat locus coeruleus neurons.
P2860
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P2860
Mu-opioid receptor desensitization: is morphine different?
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Mu-opioid receptor desensitization: is morphine different?
@ast
Mu-opioid receptor desensitization: is morphine different?
@en
type
label
Mu-opioid receptor desensitization: is morphine different?
@ast
Mu-opioid receptor desensitization: is morphine different?
@en
prefLabel
Mu-opioid receptor desensitization: is morphine different?
@ast
Mu-opioid receptor desensitization: is morphine different?
@en
P2860
P356
P1476
Mu-opioid receptor desensitization: is morphine different?
@en
P2093
MacDonald J Christie
P2860
P304
P356
10.1038/SJ.BJP.0705938
P407
P577
2004-10-25T00:00:00Z