A molecular switch that controls cell spreading and retraction. - Wikidata - wikimedia - TriplyDB

A molecular switch that controls cell spreading and retraction.

A molecular switch that controls cell spreading and retraction.

http://www.wikidata.org/entity/Q36119672

about

Talin contains a C-terminal calpain2 cleavage site important in focal adhesion dynamics Headpiece domain of dematin regulates calcium mobilization and signaling in platelets IP-10 induces dissociation of newly formed blood vessels PKC and AKT Modulate cGMP/PKG Signaling Pathway on Platelet Aggregation in Experimental Sepsis MMP7 shedding of syndecan-1 facilitates re-epithelialization by affecting alpha(2)beta(1) integrin activation An important role of the SRC family kinase Lyn in stimulating platelet granule secretion Cell adhesion: integrating cytoskeletal dynamics and cellular tension.RGT, a synthetic peptide corresponding to the integrin beta 3 cytoplasmic C-terminal sequence, selectively inhibits outside-in signaling in human platelets by disrupting the interaction of integrin alpha IIb beta 3 with Src kinase.PTP1B triggers integrin-mediated repression of myosin activity and modulates cell contractility.Neurite consolidation is an active process requiring constant repression of protrusive activity.The calpain small subunit regulates cell-substrate mechanical interactions during fibroblast migration.The small Rho GTPase Cdc42 regulates neutrophil polarity via CD11b integrin signaling A directional switch of integrin signalling and a new anti-thrombotic strategy.Identification of the integrin β3 L718P mutation in a pedigree with autosomal dominant thrombocytopenia with anisocytosis.Targeting integrin and integrin signaling in treating thrombosis.Cytoskeletal perturbation leads to platelet dysfunction and thrombocytopenia in variant forms of Glanzmann thrombasthenia G protein subunit Galpha13 binds to integrin alphaIIbbeta3 and mediates integrin "outside-in" signaling Alpha v beta3 integrin spatially regulates VASP and RIAM to control adhesion dynamics and migration.Role of calpain-mediated p53 truncation in semaphorin 3A-induced axonal growth regulation Paired immunoglobulin-like receptor B regulates platelet activation.Integrin αIIb-mediated PI3K/Akt activation in platelets.The biochemistry of memory: The 26year journey of a 'new and specific hypothesis'.The role of mechanical force and ROS in integrin-dependent signals Elastic behavior and platelet retraction in low- and high-density fibrin gels.The filamins: organizers of cell structure and function Signaling during platelet adhesion and activation The Bordetella pertussis adenylate cyclase toxin binds to T cells via LFA-1 and induces its disengagement from the immune synapse Calpain-6, a target molecule of glucocorticoids, regulates osteoclastic bone resorption via cytoskeletal organization and microtubule acetylation.Tyrosine phosphorylated c-Cbl regulates platelet functional responses mediated by outside-in signaling Distinct roles for Rap1b protein in platelet secretion and integrin αIIbβ3 outside-in signaling Fluid shear stress and sphingosine 1-phosphate activate calpain to promote membrane type 1 matrix metalloproteinase (MT1-MMP) membrane translocation and endothelial invasion into three-dimensional collagen matrices.JAM-A protects from thrombosis by suppressing integrin αIIbβ3-dependent outside-in signaling in platelets.Calpain-mediated vimentin cleavage occurs upstream of MT1-MMP membrane translocation to facilitate endothelial sprout initiation.Peptide LSARLAF induces integrin β3 dependent outside-in signaling in platelets.The interaction of Gα13 with integrin β1 mediates cell migration by dynamic regulation of RhoA Functional Effect of the Mutations Similar to the Cleavage during Platelet Activation at Integrin β3 Cytoplasmic Tail when Expressed in Mouse Platelets Characterization of a Novel Integrin Binding Protein, VPS33B, Which Is Important for Platelet Activation and In Vivo Thrombosis and Hemostasis.Investigations of human platelet-type 12-lipoxygenase: role of lipoxygenase products in platelet activation.The Src family kinases and protein kinase C synergize to mediate Gq-dependent platelet activation.Src family tyrosine kinase Lyn mediates VWF/GPIb-IX-induced platelet activation via the cGMP signaling pathway.

P2860

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P2860

A molecular switch that controls cell spreading and retraction.

http://www.wikidata.org/entity/Q36119672

description

2007 nî lūn-bûn

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

@zh-tw

2007年论文

@wuu

2007年论文

@zh

2007年论文

@zh-cn

name

A molecular switch that controls cell spreading and retraction.

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A molecular switch that controls cell spreading and retraction.

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type

label

A molecular switch that controls cell spreading and retraction.

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A molecular switch that controls cell spreading and retraction.

@en

prefLabel

A molecular switch that controls cell spreading and retraction.

@ast

A molecular switch that controls cell spreading and retraction.

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Journal of Cell Biology

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A molecular switch that controls cell spreading and retraction.

@en

P2093

Aleksandra Stojanovic

http://www.w3.org/2001/XMLSchema#string

Athar Chishti

http://www.w3.org/2001/XMLSchema#string

Emily Welch

http://www.w3.org/2001/XMLSchema#string

Haixia Gong

http://www.w3.org/2001/XMLSchema#string

Panagiotis Flevaris

http://www.w3.org/2001/XMLSchema#string

Xiaoping Du

http://www.w3.org/2001/XMLSchema#string

P2860

Structural basis of integrin activation by talin

Coordinate interactions of Csk, Src, and Syk kinases with [alpha]IIb[beta]3 initiate integrin signaling to the cytoskeleton

Src kinase activation by direct interaction with the integrin beta cytoplasmic domain

PTP-1B is an essential positive regulator of platelet integrin signaling

Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)

A structural mechanism of integrin alpha(IIb)beta(3) "inside-out" activation as regulated by its cytoplasmic face

Integrins: bidirectional, allosteric signaling machines

Sequential activation of p38 and ERK pathways by cGMP-dependent protein kinase leading to activation of the platelet integrin alphaIIb beta3

Integrins: dynamic scaffolds for adhesion and signaling in platelets

Calpain cleavage of the cytoplasmic domain of the integrin beta 3 subunit

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553-565

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10.1083/JCB.200703185

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3

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179

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17967945

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2064799

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