The interleukin 2 CD28-responsive complex contains at least three members of the NF kappa B family: c-Rel, p50, and p65.
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A novel NF-kappa B complex containing p65 homodimers: implications for transcriptional control at the level of subunit dimerizationOpposing roles of serine/threonine kinases MEKK1 and LOK in regulating the CD28 responsive element in T-cellsThe quantal theory of how the immune system discriminates between "self and non-self"Role of T cell-nuclear factor κB in transplantationTranscriptional Activation of the Interleukin-2 Promoter by Hepatitis C Virus Core ProteinRole of transcriptional repressor ICER in cyclic AMP-mediated attenuation of cytokine gene expression in human thymocytesTacrolimus inhibits NF-κB activation in peripheral human T cellsNF-kappa B RelA-deficient lymphocytes: normal development of T cells and B cells, impaired production of IgA and IgG1 and reduced proliferative responsesA single amino acid alteration in cytoplasmic domain determines IL-2 promoter activation by ligation of CD28 but not inducible costimulator (ICOS)Proline residues in CD28 and the Src homology (SH)3 domain of Lck are required for T cell costimulationMicropatterning of costimulatory ligands enhances CD4+ T cell function.Akt provides the CD28 costimulatory signal for up-regulation of IL-2 and IFN-gamma but not TH2 cytokines.ROG negatively regulates T-cell activation but is dispensable for Th-cell differentiation.Novel CD28-responsive enhancer activated by CREB/ATF and AP-1 families in the human interleukin-2 receptor alpha-chain locusThe clinical implication and molecular mechanism of preferential IL-4 production by modified glycolipid-stimulated NKT cells.Negative transcriptional regulation in anergic T cells.Regulation of the interleukin-2 CD28-responsive element by NF-ATp and various NF-kappaB/Rel transcription factors.Identification of a DNA binding site for the nuclear factor YY1 in the human GM-CSF core promoter.NF-kappa B activation induced by T cell receptor/CD28 costimulation is mediated by protein kinase C-thetaNF-κB in immunobiology.Distinct mechanisms of immunosuppression as a consequence of major surgeryIFN-β Selectively Inhibits IL-2 Production through CREM-Mediated Chromatin Remodeling.An essential role for nuclear factor kappaB in promoting double positive thymocyte apoptosis.Costimulation of cytokine gene expression in T cells by the human T leukemia/lymphotropic virus type 1 trans activator Tax.Activation of the IL-2 gene promoter by HTLV-I tax involves induction of NF-AT complexes bound to the CD28-responsive element.The Rel subunit of NF-kappaB-like transcription factors is a positive and negative regulator of macrophage gene expression: distinct roles for Rel in different macrophage populationsBiochemical and cellular characterization of transcription factors binding to the hyperconserved core promoter-associated M4 motif.CD28 promotes CD4+ T cell clonal expansion during infection independently of its YMNM and PYAP motifs.Combined deficiency of p50 and cRel in CD4+ T cells reveals an essential requirement for nuclear factor kappaB in regulating mature T cell survival and in vivo functionThe quantal theory of immunity.IL-2 production in developing Th1 cells is regulated by heterodimerization of RelA and T-bet and requires T-bet serine residue 508.v-rel Induces ectopic expression of an adhesion molecule, DM-GRASP, during B-lymphoma developmentRelA is a potent transcriptional activator of the CD28 response element within the interleukin 2 promoter.Basal phosphorylation of the PEST domain in the I(kappa)B(beta) regulates its functional interaction with the c-rel proto-oncogene product.CD28 mediates a potent costimulatory signal for rapid degradation of IkappaBbeta which is associated with accelerated activation of various NF-kappaB/Rel heterodimers.v-rel induces expression of three avian immunoregulatory surface receptors more efficiently than c-rel.Evolution of the oncogenic potential of v-rel: rel-induced expression of immunoregulatory receptors correlates with tumor development and in vitro transformationEffect of CD28 signal transduction on c-Rel in human peripheral blood T cells.A cis element required for induction of the interleukin 2 enhancer by human T-cell leukemia virus type I binds a novel Tax-inducible nuclear protein.Nuclear factor kappa B-dependent activation of the antiapoptotic bfl-1 gene by the Epstein-Barr virus latent membrane protein 1 and activated CD40 receptor.
P2860
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P2860
The interleukin 2 CD28-responsive complex contains at least three members of the NF kappa B family: c-Rel, p50, and p65.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh
1993年學術文章
@zh-hant
name
The interleukin 2 CD28-respons ...... B family: c-Rel, p50, and p65.
@ast
The interleukin 2 CD28-respons ...... B family: c-Rel, p50, and p65.
@en
type
label
The interleukin 2 CD28-respons ...... B family: c-Rel, p50, and p65.
@ast
The interleukin 2 CD28-respons ...... B family: c-Rel, p50, and p65.
@en
prefLabel
The interleukin 2 CD28-respons ...... B family: c-Rel, p50, and p65.
@ast
The interleukin 2 CD28-respons ...... B family: c-Rel, p50, and p65.
@en
P2093
P2860
P356
P1476
The interleukin 2 CD28-respons ...... B family: c-Rel, p50, and p65.
@en
P2093
P2860
P304
P356
10.1073/PNAS.90.5.1696
P407
P577
1993-03-01T00:00:00Z