Toward a unified theory of caloric restriction and longevity regulation.
about
Epigenetic regulation of caloric restriction in agingLife span extension by calorie restriction depends on Rim15 and transcription factors downstream of Ras/PKA, Tor, and Sch9Increased life span due to calorie restriction in respiratory-deficient yeastSIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during agingSIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stressSIRT1 suppresses beta-amyloid production by activating the alpha-secretase gene ADAM10.The prolongevity effect of resveratrol depends on dietary composition and calorie intake in a tephritid fruit flyGenome-environment interactions that modulate aging: powerful targets for drug discoveryChemical genetic screen identifies lithocholic acid as an anti-aging compound that extends yeast chronological life span in a TOR-independent manner, by modulating housekeeping longevity assurance processesSIRT1 promotes the central adaptive response to diet restriction through activation of the dorsomedial and lateral nuclei of the hypothalamus.Chronic ingestion of 2-deoxy-D-glucose induces cardiac vacuolization and increases mortality in ratsThe importance of hormesis to public healthDelay of T cell senescence by caloric restriction in aged long-lived nonhuman primatesThioredoxin and ventricular remodelingCalorie restriction extends life span--but which calories?The Epigenetic Pathways to Ribosomal DNA SilencingPolyphenol Stilbenes: Molecular Mechanisms of Defence against Oxidative Stress and Aging-Related DiseasesAmino acid homeostasis and chronological longevity in Saccharomyces cerevisiaeBenefits of short-term dietary restriction in mammalsDietary epigenetics in cancer and agingEndogenous hydrogen sulfide production is essential for dietary restriction benefitsExercise-training in young Drosophila melanogaster reduces age-related decline in mobility and cardiac performanceRole of the hypothalamus in mediating protective effects of dietary restriction during agingResveratrol improves health and survival of mice on a high-calorie dietMSN2 and MSN4 link calorie restriction and TOR to sirtuin-mediated lifespan extension in Saccharomyces cerevisiae.Better Living through Chemistry: Caloric Restriction (CR) and CR Mimetics Alter Genome Function to Promote Increased Health and LifespanSlowing ageing by design: the rise of NAD(+) and sirtuin-activating compoundsXenohormetic and anti-aging activity of secoiridoid polyphenols present in extra virgin olive oil: a new family of gerosuppressant agentsResveratrol inhibits β-amyloid-induced neuronal apoptosis through regulation of SIRT1-ROCK1 signaling pathwayMetabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alphaA nutrient-sensitive interaction between Sirt1 and HNF-1α regulates Crp expressionBigger teeth for longer life? Longevity and molar height in two roe deer populationsMammalian sirtuins: biological insights and disease relevanceTissue vitamin concentrations are maintained constant by changing the urinary excretion rate of vitamins in rats' restricted food intake.Mimetics of hormetic agents: stress-resistance triggersDNA replication stress is a determinant of chronological lifespan in budding yeast.Nutrient-enhanced diet reduces noise-induced damage to the inner ear and hearing loss.Age-related hearing loss: is it a preventable condition?Adaptive capability as indicated by behavioral and physiological responses, plasma HSP70 level, and PBMC HSP70 mRNA expression in Osmanabadi goats subjected to combined (heat and nutritional) stressors.The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth
P2860
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P2860
Toward a unified theory of caloric restriction and longevity regulation.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Toward a unified theory of caloric restriction and longevity regulation.
@ast
Toward a unified theory of caloric restriction and longevity regulation.
@en
type
label
Toward a unified theory of caloric restriction and longevity regulation.
@ast
Toward a unified theory of caloric restriction and longevity regulation.
@en
prefLabel
Toward a unified theory of caloric restriction and longevity regulation.
@ast
Toward a unified theory of caloric restriction and longevity regulation.
@en
P1476
Toward a unified theory of caloric restriction and longevity regulation.
@en
P304
P356
10.1016/J.MAD.2005.03.019
P577
2005-09-01T00:00:00Z