Single amino acid modification of adeno-associated virus capsid changes transduction and humoral immune profiles. - Wikidata - wikimedia - TriplyDB

Single amino acid modification of adeno-associated virus capsid changes transduction and humoral immune profiles.

Single amino acid modification of adeno-associated virus capsid changes transduction and humoral immune profiles.

http://www.wikidata.org/entity/Q36171820

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Targeted approaches to induce immune tolerance for Pompe disease therapy Adeno-associated Virus as a Mammalian DNA Vector Adeno-associated virus at 50: a golden anniversary of discovery, research, and gene therapy success--a personal perspective Development of Patient-specific AAV Vectors After Neutralizing Antibody Selection for Enhanced Muscle Gene Transfer Adenosine kinase, glutamine synthetase and EAAT2 as gene therapy targets for temporal lobe epilepsy.Influence of immune responses in gene/stem cell therapies for muscular dystrophies.Adeno-associated virus (AAV) vectors in gene therapy: immune challenges and strategies to circumvent them.Recombinant adeno-associated virus utilizes cell-specific infectious entry mechanisms Optimization of the capsid of recombinant adeno-associated virus 2 (AAV2) vectors: the final threshold?Targeting photoreceptors via intravitreal delivery using novel, capsid-mutated AAV vectors.Promoterless gene targeting without nucleases ameliorates haemophilia B in mice.Vector design Tour de Force: integrating combinatorial and rational approaches to derive novel adeno-associated virus variants Controlling AAV Tropism in the Nervous System with Natural and Engineered Capsids.Reprogramming Immune Response With Capsid-Optimized AAV6 Vectors for Immunotherapy of Cancer Induction of Immune Tolerance to Foreign Protein via Adeno-Associated Viral Vector Gene Transfer in Mid-Gestation Fetal Sheep.Prediction of adeno-associated virus neutralizing antibody activity for clinical application.Arsenic trioxide stabilizes accumulations of adeno-associated virus virions at the perinuclear region, increasing transduction in vitro and in vivo.BK polyomavirus genotypes represent distinct serotypes with distinct entry tropism.An emerging adeno-associated viral vector pipeline for cardiac gene therapy Heparan Sulfate Binding Promotes Accumulation of Intravitreally Delivered Adeno-associated Viral Vectors at the Retina for Enhanced Transduction but Weakly Influences Tropism.Direct interaction of human serum proteins with AAV virions to enhance AAV transduction: immediate impact on clinical applications Promise and problems associated with the use of recombinant AAV for the delivery of anti-HIV antibodies Pre-Clinical Assessment of Immune Responses to Adeno-Associated Virus (AAV) Vectors.Recent advances in gene therapy for lysosomal storage disorders.Application of polyploid adeno-associated virus vectors for transduction enhancement and neutralizing antibody evasion.Characterization of the Adeno-Associated Virus 1 and 6 Sialic Acid Binding Site Rationally designed capsid and transgene cassette of AAV6 vectors for dendritic cell-based cancer immunotherapy.BK Polyomavirus: Clinical Aspects, Immune Regulation, and Emerging Therapies.Promise of adeno-associated virus as a gene therapy vector for cardiovascular diseases.Adeno-Associated Virus (AAV) as a Vector for Gene Therapy.Gene Delivery of Activated Factor VII Using Alternative Adeno-Associated Virus Serotype Improves Hemostasis in Hemophiliac Mice with FVIII Inhibitors and Adeno-Associated Virus Neutralizing Antibodies.Systemic Vascular Transduction by Capsid Mutant Adeno-Associated Virus After Intravenous Injection.scAAVIL-1ra dosing trial in a large animal model and validation of long-term expression with repeat administration for osteoarthritis therapy.AAV8 Can Induce Innate and Adaptive Immune Response in the Primate Eye.Neutralizing antibodies against AAV2, AAV5 and AAV8 in healthy and HIV-1-infected subjects in China: implications for gene therapy using AAV vectors.Mapping the Structural Determinants Required for AAVrh.10 Transport across the Blood-Brain Barrier.AAV8 virions hijack serum proteins to increase hepatocyte binding for transduction enhancement.

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P2860

Single amino acid modification of adeno-associated virus capsid changes transduction and humoral immune profiles.

http://www.wikidata.org/entity/Q36171820

description

2012 nî lūn-bûn

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Single amino acid modification ...... n and humoral immune profiles.

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Single amino acid modification ...... n and humoral immune profiles.

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Single amino acid modification ...... n and humoral immune profiles.

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Single amino acid modification ...... n and humoral immune profiles.

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Single amino acid modification ...... n and humoral immune profiles.

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Single amino acid modification ...... n and humoral immune profiles.

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Journal of Virology

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Single amino acid modification ...... n and humoral immune profiles.

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P2093

Aravind Asokan

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Chengwen Li

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Dawn E Bowles

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Joseph Rabinowitz

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Matthew L Hirsch

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Nina Diprimio

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Paul E Monahan

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R Jude Samulski

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P2860

CD40 AND CD154 IN CELL-MEDIATED IMMUNITY

Production of high-titer recombinant adeno-associated virus vectors in the absence of helper adenovirus

Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy

Safety and efficacy of gene transfer for Leber's congenital amaurosis

Age-dependent effects of RPE65 gene therapy for Leber's congenital amaurosis: a phase 1 dose-escalation trial

Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

Optimization of stealth adeno-associated virus vectors by randomization of immunogenic epitopes.

Directed evolution of adeno-associated virus yields enhanced gene delivery vectors.

Engineering and selection of shuffled AAV genomes: a new strategy for producing targeted biological nanoparticles.

Cloning and characterization of adeno-associated virus type 5.

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7752-7759

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10.1128/JVI.00675-12

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15

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86

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Mavis Agbandje-McKenna

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2012-05-16T00:00:00Z

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22593151

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3421647

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