The nuclear receptor LRH-1 critically regulates extra-adrenal glucocorticoid synthesis in the intestine
about
Structural basis of coactivation of liver receptor homolog-1 by -cateninThe macrophage migration inhibitory factor homolog of Entamoeba histolytica binds to and immunomodulates host macrophages.The small heterodimer partner is a gonadal gatekeeper of sexual maturation in male mice.11β-hydroxysteroid dehydrogenase 1 specific inhibitor increased dermal collagen content and promotes fibroblast proliferation.TNF suppresses acute intestinal inflammation by inducing local glucocorticoid synthesis.Nuclear receptors: mediators and modifiers of inflammation-induced cholestasis.Extra-adrenal glucocorticoids and mineralocorticoids: evidence for local synthesis, regulation, and function.Liver receptor homolog 1 is essential for ovulation.Cortisol synthesis in epidermis is induced by IL-1 and tissue injury.Nuclear receptor liver receptor homologue 1 (LRH-1) regulates pancreatic cancer cell growth and proliferation.Intestinal epithelium-specific knockout of the cytochrome P450 reductase gene exacerbates dextran sulfate sodium-induced colitisLRH-1-mediated glucocorticoid synthesis in enterocytes protects against inflammatory bowel disease.Local corticosterone production and angiotensin-I converting enzyme shedding in a mouse model of intestinal inflammationLiver receptor homolog-1 (LRH-1): a potential therapeutic target for cancerCompromised intestinal lipid absorption in mice with a liver-specific deficiency of liver receptor homolog 1.Liver receptor homolog-1 regulates bile acid homeostasis but is not essential for feedback regulation of bile acid synthesis.Emerging actions of the nuclear receptor LRH-1 in the gut.Local corticosterone activation by 11β-hydroxysteroid dehydrogenase 1 in keratinocytes: the role in narrow-band UVB-induced dermatitis.Glucocorticoids alleviate intestinal ER stress by enhancing protein folding and degradation of misfolded proteins.The steroidogenic enzyme Cyp11a1 is essential for development of peanut-induced intestinal anaphylaxis.Why does the gut synthesize glucocorticoids?Regulation of anti-atherogenic apolipoprotein M gene expression by the orphan nuclear receptor LRH-1.Sirtuin 4 Regulates Lipopolysaccharide Mediated Leydig Cell Dysfunction.Liver receptor homolog-1 (NR5a2) regulates CD95/Fas ligand transcription and associated T-cell effector functions.Tumor necrosis factor suppresses NR5A2 activity and intestinal glucocorticoid synthesis to sustain chronic colitis.Local glucocorticoid production in the mouse lung is induced by immune cell stimulation.Interleukin-1 receptor antagonist induction as an additional mechanism for liver receptor homolog-1 to negatively regulate the hepatic acute phase response.Colon cancer cells produce immunoregulatory glucocorticoidsACTH-induced cortisol release is related to the copy number of the C4B gene encoding the fourth component of complement in patients with non-functional adrenal incidentaloma.The reprogramming factor nuclear receptor subfamily 5, group A, member 2 cannot replace octamer-binding transcription factor 4 function in the self-renewal of embryonic stem cells.Nr5a2 heterozygosity sensitises to, and cooperates with, inflammation in KRas(G12V)-driven pancreatic tumourigenesis.Colon cancer cells produce immunoregulatory glucocorticoids.The curious case of Gαs gain-of-function in neoplasia.Liver receptor homolog-1 is critical for adequate up-regulation of Cyp7a1 gene transcription and bile salt synthesis during bile salt sequestration
P2860
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P2860
The nuclear receptor LRH-1 critically regulates extra-adrenal glucocorticoid synthesis in the intestine
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
The nuclear receptor LRH-1 cri ...... oid synthesis in the intestine
@ast
The nuclear receptor LRH-1 cri ...... oid synthesis in the intestine
@en
type
label
The nuclear receptor LRH-1 cri ...... oid synthesis in the intestine
@ast
The nuclear receptor LRH-1 cri ...... oid synthesis in the intestine
@en
prefLabel
The nuclear receptor LRH-1 cri ...... oid synthesis in the intestine
@ast
The nuclear receptor LRH-1 cri ...... oid synthesis in the intestine
@en
P2093
P2860
P356
P1476
The nuclear receptor LRH-1 cri ...... oid synthesis in the intestine
@en
P2093
Andrea Fuhrer
Kristina Schoonjans
Matthias Mueller
Sabine Jakob
Thomas Brunner
P2860
P304
P356
10.1084/JEM.20060357
P407
P577
2006-08-21T00:00:00Z