The CD28 ligand B7/BB1 provides costimulatory signal for alloactivation of CD4+ T cells.
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p56Lck and p59Fyn regulate CD28 binding to phosphatidylinositol 3-kinase, growth factor receptor-bound protein GRB-2, and T cell-specific protein-tyrosine kinase ITK: implications for T-cell costimulationCTLA-4 binding to the lipid kinase phosphatidylinositol 3-kinase in T cellsT helper cell activation and human retroviral pathogenesisStructure, expression, and T cell costimulatory activity of the murine homologue of the human B lymphocyte activation antigen B7Differential regulation of B7 mRNA in enterocytes and lymphoid cellsHeat-stable antigen is a costimulatory molecule for CD4 T cell growthCD43 is a murine T cell costimulatory receptor that functions independently of CD28Exposure to abatacept or rituximab in the first trimester of pregnancy in three women with autoimmune diseases.Perforin and IL-2 upregulation define qualitative differences among highly functional virus-specific human CD8 T cellsCytokine profiles associated with induction of the anticryptococcal cell-mediated immune responseUnderstanding the mechanism of action of bacterial superantigens from a decade of research.Immunopathogenesis of thyroid eye disease: emerging paradigmsDevelopment of human T-cell leukemia virus type 1-transformed tumors in rats following suppression of T-cell immunity by CD80 and CD86 blockadeFrom the study of tumor cell immunogenicity to the generation of antitumor cytotoxic cells in non-Hodgkin's lymphomas.Bee venom allergy.Antibody to the ligand of CD40, gp39, blocks the occurrence of the acute and chronic forms of graft-vs-host diseaseAbatacept: a costimulatory inhibitor for treatment of rheumatoid arthritis.Autoimmunity correlates with tumor regression in patients with metastatic melanoma treated with anti-cytotoxic T-lymphocyte antigen-4.The therapeutic potential of costimulatory blockade with CTLA4Ig in rheumatoid arthritis.Mice expressing both B7-1 and viral glycoprotein on pancreatic beta cells along with glycoprotein-specific transgenic T cells develop diabetes due to a breakdown of T-lymphocyte unresponsivenessCostimulator B7-1 confers antigen-presenting-cell function to parenchymal tissue and in conjunction with tumor necrosis factor alpha leads to autoimmunity in transgenic mice.The B7/BB1 antigen provides one of several costimulatory signals for the activation of CD4+ T lymphocytes by human blood dendritic cells in vitro.The T cell antigen receptor CD3:CD4 molecular complex is diminished on the surface of pulmonary lymphocytesAntiviral immune responses in CTLA4 transgenic mice.An integrated view of suppressor T cell subsets in immunoregulationEffect of Chronic Uremia on the Cell Surface Expression of B7 Family Costimulatory Molecules in an HLA-A2 Transgenic Mouse Model of Chronic Kidney Disease.The interleukin 2 CD28-responsive complex contains at least three members of the NF kappa B family: c-Rel, p50, and p65.Crosslinking of the T cell-specific accessory molecules CD7 and CD28 modulates T cell adhesionAntibody and B7/BB1-mediated ligation of the CD28 receptor induces tyrosine phosphorylation in human T cellsDifferential induction of transcription factors that regulate the interleukin 2 gene during anergy induction and restimulationCoexpression and functional cooperation of CTLA-4 and CD28 on activated T lymphocytes.Intrapatient dose escalation of anti-CTLA-4 antibody in patients with metastatic melanoma.Prognostic factors related to clinical response in patients with metastatic melanoma treated by CTL-associated antigen-4 blockade.Induction of alloantigen-specific hyporesponsiveness in human T lymphocytes by blocking interaction of CD28 with its natural ligand B7/BB1Activated T cells induce expression of B7/BB1 on normal or leukemic B cells through a CD40-dependent signalPeptide-major histocompatibility complex class II complexes with mixed agonist/antagonist properties provide evidence for ligand-related differences in T cell receptor-dependent intracellular signalingCD28-B7 interactions allow the induction of CD8+ cytotoxic T lymphocytes in the absence of exogenous help.Small amounts of superantigen, when presented on dendritic cells, are sufficient to initiate T cell responses.Costimulator deficient antigen presentation by an endothelial cell line induces a nonproliferative T cell activation response without anergy.B7 but not intercellular adhesion molecule-1 costimulation prevents the induction of human alloantigen-specific tolerance.
P2860
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P2860
The CD28 ligand B7/BB1 provides costimulatory signal for alloactivation of CD4+ T cells.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
The CD28 ligand B7/BB1 provides costimulatory signal for alloactivation of CD4+ T cells.
@ast
The CD28 ligand B7/BB1 provides costimulatory signal for alloactivation of CD4+ T cells.
@en
type
label
The CD28 ligand B7/BB1 provides costimulatory signal for alloactivation of CD4+ T cells.
@ast
The CD28 ligand B7/BB1 provides costimulatory signal for alloactivation of CD4+ T cells.
@en
prefLabel
The CD28 ligand B7/BB1 provides costimulatory signal for alloactivation of CD4+ T cells.
@ast
The CD28 ligand B7/BB1 provides costimulatory signal for alloactivation of CD4+ T cells.
@en
P2093
P2860
P356
P1476
The CD28 ligand B7/BB1 provides costimulatory signal for alloactivation of CD4+ T cells.
@en
P2093
P2860
P304
P356
10.1084/JEM.173.3.759
P407
P577
1991-03-01T00:00:00Z