Mammalian PAR-1 determines epithelial lumen polarity by organizing the microtubule cytoskeleton.
about
Dynein modifiers in C. elegans: light chains suppress conditional heavy chain mutantsMARK2/EMK1/Par-1Balpha phosphorylation of Rab11-family interacting protein 2 is necessary for the timely establishment of polarity in Madin-Darby canine kidney cellsActive transport of the ubiquitin ligase MID1 along the microtubules is regulated by protein phosphatase 2AThe polarity protein Par1b/EMK/MARK2 regulates T cell receptor-induced microtubule-organizing center polarizationRab11a and myosin Vb are required for bile canalicular formation in WIF-B9 cellsThe yeast par-1 homologs kin1 and kin2 show genetic and physical interactions with components of the exocytic machineryPar-1 promotes a hepatic mode of apical protein trafficking in MDCK cellsBright and stable near-infrared fluorescent protein for in vivo imagingHelicobacter pylori in gastric carcinogenesis: mechanismsPolarity in mammalian epithelial morphogenesisPar1b induces asymmetric inheritance of plasma membrane domains via LGN-dependent mitotic spindle orientation in proliferating hepatocytesAutomated screening of microtubule growth dynamics identifies MARK2 as a regulator of leading edge microtubules downstream of Rac1 in migrating cellsInduction of lateral lumens through disruption of a monoleucine-based basolateral-sorting motif in betacellulinA protein interaction map for cell-cell adhesion regulators identifies DUSP23 as a novel phosphatase for β-catenin.Mutations in TRAF3IP1/IFT54 reveal a new role for IFT proteins in microtubule stabilizationEffects of T208E activating mutation on MARK2 protein structure and dynamics: Modeling and simulation.The signaling adaptor GAB1 regulates cell polarity by acting as a PAR protein scaffold.The serine/threonine kinase Par1b regulates epithelial lumen polarity via IRSp53-mediated cell-ECM signaling.The PAR proteins: fundamental players in animal cell polarization.Par1b promotes hepatic-type lumen polarity in Madin Darby canine kidney cells via myosin II- and E-cadherin-dependent signaling.Phosphorylation of Rab11-FIP2 regulates polarity in MDCK cells.Nephrons require Rho-kinase for proximal-distal polarity developmentCytokinesis defines a spatial landmark for hepatocyte polarization and apical lumen formation.IGF-1 modulates gene expression of proteins involved in inflammation, cytoskeleton, and liver architecture.Structure and regulation of MARK, a kinase involved in abnormal phosphorylation of Tau protein.Jaagsiekte sheep retrovirus transformation in Madin-Darby canine kidney epithelial cell three-dimensional culture.Differential roles for actin polymerization and a myosin II motor in assembly of the epithelial apical junctional complex.Microtubule affinity regulating kinase activity in living neurons was examined by a genetically encoded fluorescence resonance energy transfer/fluorescence lifetime imaging-based biosensor: inhibitors with therapeutic potential.KIF17 stabilizes microtubules and contributes to epithelial morphogenesis by acting at MT plus ends with EB1 and APC.Regulatory dissociation of Tctex-1 light chain from dynein complex is essential for the apical delivery of rhodopsin.PAR1b promotes cell-cell adhesion and inhibits dishevelled-mediated transformation of Madin-Darby canine kidney cells.Septin GTPases spatially guide microtubule organization and plus end dynamics in polarizing epithelia"Targeted disruption of the epithelial-barrier by Helicobacter pylori".Regulation of epithelial tight junction assembly and disassembly by AMP-activated protein kinase.ROCK1-directed basement membrane positioning coordinates epithelial tissue polarity.Loss of the Par-1b/MARK2 polarity kinase leads to increased metabolic rate, decreased adiposity, and insulin hypersensitivity in vivoAMP-activated protein kinase regulates the assembly of epithelial tight junctions.An oskar-dependent positive feedback loop maintains the polarity of the Drosophila oocyte.Loss of Liver Kinase B1 (LKB1) in Beta Cells Enhances Glucose-stimulated Insulin Secretion Despite Profound Mitochondrial Defects.Coordinated protein sorting, targeting and distribution in polarized cells
P2860
Q21092488-42B92A6D-DE66-4C3E-8ADB-5408219188CCQ24293530-0B445613-D82D-4E23-8D3A-2AF50D88F752Q24337034-79E195F5-4F06-49D0-AA6F-ACF3907AD9AAQ24339248-A73EEA98-FF5C-42CF-851D-965BA06653AEQ24536054-F17D822E-943C-4A3C-9332-C2A155420D1AQ24557447-98726721-0CD2-4285-A1AA-6E7F20E38EABQ24564641-DD82E4D5-39BF-4C0D-A056-9C445C5BDC9DQ24621011-06C61FC7-72DC-40D5-AA34-0299AE6A7765Q26821843-5B34B477-4B86-4725-B4DD-3E654C0AA0F7Q26830318-A33EA388-F239-4496-856E-EB5C3D41790AQ27316277-612EB432-EBD3-43B1-A034-46F4DA2A583EQ27332112-8B03A83C-71BF-4703-996A-98A3B5A6EB8FQ27339929-AB38AA3C-A0B1-4CB0-A187-3BA4906C8143Q27348104-4BB6C74A-2713-491E-A6C9-37A28EF60194Q28119115-F2191CDB-E951-412F-B4FD-06EF6721B417Q30395205-BAC5FCEC-A479-45C0-92B0-63D8B02252EBQ30417702-5B0C13A0-4BD0-4789-B875-2CA84077E701Q30431153-B68E8E8E-83E3-4BFE-BA04-450511D90341Q30434403-18445044-8384-4F23-B62A-402DB69706D5Q30444602-7B3054F2-FC18-4145-8C7B-58B5DCF7562CQ30515963-B565B4CF-A0D2-41C7-ACC6-3BEB1E0A71A0Q30544951-1FA28B8D-6F6C-408A-8D6F-0203F6EAC50BQ30579254-73AF916F-04D7-4FC6-AE39-4F0FC1CD041FQ30846570-1AFD592F-FEBD-432E-BAAB-F257F3B2EA82Q30855139-5D2F0585-254E-4B77-BD83-D593EDA7994FQ33826793-5CB01EF5-2B8A-4C66-90AD-0BAD41665897Q33841357-0E1E0915-80DE-4A4F-A42A-E9739D422A6BQ34044781-565F00E4-D845-420F-9AF1-F61A64F56341Q34069997-EDCE8B01-28DB-4249-9D19-6E4714E738AEQ34563926-3926FFC8-DAA8-45C9-95B1-29045D00A45FQ34886029-73C099FF-65D5-4C17-BF88-B0DB506E1C3DQ35130198-39D762DD-EB91-4004-A2B0-B122E88EC2D4Q35576548-0CD30B78-AE53-470F-85CA-17518409708AQ35612267-D67C4987-81D4-471C-98D8-68E6828032A4Q35624852-51A8E8B6-AF1F-41E3-A881-443F1DBC6E2DQ35720274-AA2C16B0-05C8-4A21-AFBD-3549E9A46C82Q35768585-C05BA3E6-B791-4CBB-AF2A-29ADF90806C9Q35830113-A7A60D64-6979-4BF6-A699-0147126689A6Q35978253-F785B6DF-5AFE-4BB3-8594-A90C0BCDDE8FQ36015653-40A58BBA-EC81-4874-8FB3-9ADF432E8E61
P2860
Mammalian PAR-1 determines epithelial lumen polarity by organizing the microtubule cytoskeleton.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Mammalian PAR-1 determines epi ...... the microtubule cytoskeleton.
@ast
Mammalian PAR-1 determines epi ...... the microtubule cytoskeleton.
@en
type
label
Mammalian PAR-1 determines epi ...... the microtubule cytoskeleton.
@ast
Mammalian PAR-1 determines epi ...... the microtubule cytoskeleton.
@en
prefLabel
Mammalian PAR-1 determines epi ...... the microtubule cytoskeleton.
@ast
Mammalian PAR-1 determines epi ...... the microtubule cytoskeleton.
@en
P2093
P2860
P356
P1476
Mammalian PAR-1 determines epi ...... the microtubule cytoskeleton.
@en
P2093
Anne Müsch
David Cohen
Enrique Rodriguez-Boulan
Patrick J Brennwald
P2860
P304
P356
10.1083/JCB.200308104
P407
P577
2004-02-23T00:00:00Z