Genetic control of diabetes and insulitis in the nonobese diabetic (NOD) mouse - Wikidata - wikimedia - TriplyDB

Genetic control of diabetes and insulitis in the nonobese diabetic (NOD) mouse

Genetic control of diabetes and insulitis in the nonobese diabetic (NOD) mouse

http://www.wikidata.org/entity/Q36352723

about

Susceptibility to type I diabetes in women is associated with the CD3 epsilon locus on chromosome 11 A diabetes-associated T-cell autoantigen maps to a telomeric locus on mouse chromosome 6.Culture-independent identification of gut bacteria correlated with the onset of diabetes in a rat model.A recombination event in the 5' flanking region of the Ly-6C gene correlates with impaired expression in the NOD, NZB and ST strains of mice Use of nonobese diabetic mice to understand human type 1 diabetes Two genetic loci regulate T cell-dependent islet inflammation and drive autoimmune diabetes pathogenesis Distinct genetic control of autoimmune neuropathy and diabetes in the non-obese diabetic background.Major histocompatibility complex-linked diabetogenic gene of the nonobese diabetic mouse. Analysis of genomic DNA amplified by the polymerase chain reaction.Reversal of beta-cell suppression in vitro in pancreatic islets isolated from nonobese diabetic mice during the phase preceding insulin-dependent diabetes mellitus Unmasking genes in a type 1 diabetes-resistant mouse strain that enhances pathogenic CD8 T-cell responses.Evidence for the presence of insulin-dependent diabetes-associated alleles on the distal part of mouse chromosome 6.Genetic heterogeneity of autoimmune disorders in the nonobese diabetic mouse.High-resolution linkage mapping for susceptibility genes in human polygenic disease: insulin-dependent diabetes mellitus and chromosome 11q.Central and peripheral autoantigen presentation in immune tolerance.Identification of a new susceptibility locus for insulin-dependent diabetes mellitus by ancestral haplotype congenic mapping Recombinant human tumor necrosis factor alpha suppresses autoimmune diabetes in nonobese diabetic mice.Mouse models of type 1 and type 2 diabetes derived from the same closed colony: genetic susceptibility shared between two types of diabetes.Genetic analysis of diabetes and insulitis in an interspecific cross of the nonobese diabetic mouse with Mus spretus Abnormal T cell selection on nod thymic epithelium is sufficient to induce autoimmune manifestations in C57BL/6 athymic nude mice.Genetic dissection of T cell receptor V beta gene requirements for spontaneous murine diabetes Autoimmune syndromes in major histocompatibility complex (MHC) congenic strains of nonobese diabetic (NOD) mice. The NOD MHC is dominant for insulitis and cyclophosphamide-induced diabetes.Expression of genetically determined diabetes and insulitis in the nonobese diabetic (NOD) mouse at the level of bone marrow-derived cells. Transfer of diabetes and insulitis to nondiabetic (NOD X B10) F1 mice with bone marrow cells from NOD mice I-E+ nonobese diabetic mice develop insulitis and diabetes.Determinant capture as a possible mechanism of protection afforded by major histocompatibility complex class II molecules in autoimmune disease Resistance alleles at two non-major histocompatibility complex-linked insulin-dependent diabetes loci on chromosome 3, Idd3 and Idd10, protect nonobese diabetic mice from diabetes Local expression of transgene encoded TNF alpha in islets prevents autoimmune diabetes in nonobese diabetic (NOD) mice by preventing the development of auto-reactive islet-specific T cells Major histocompatibility complex class II molecules can protect from diabetes by positively selecting T cells with additional specificities.Analysis of the role of variation of major histocompatibility complex class II expression on nonobese diabetic (NOD) peripheral T cell response An Abd transgene prevents diabetes in nonobese diabetic mice by inducing regulatory T cells.Antigen recognition and peptide-mediated immunotherapy in autoimmune disease.Peripherin: an islet antigen that is cross-reactive with nonobese diabetic mouse class II gene products.Antigen presentation and effector mechanisms in 'auto-immune' diabetes.Establishment of an animal model using recombinant NOD.B10.D2 mice to study initial adhesion of oral streptococci.Comparative genetics: synergizing human and NOD mouse studies for identifying genetic causation of type 1 diabetes Prevention of autoimmune insulitis in nonobese diabetic mice by expression of major histocompatibility complex class I Ld molecules.Type 1 diabetes: primary antigen/peptide/register/trimolecular complex The phenotype of lymphoid cells and thymic epithelium correlates with development of autoimmune insulitis in NOD in equilibrium with C57BL/6 allophenic chimeras.Transgenic models of T-cell self tolerance and autoimmunity.How many genes code for organ-specific autoimmunity?Regulation of type 1 diabetes development and B-cell activation in nonobese diabetic mice by early life exposure to a diabetogenic environment.

P2860

Q24681586-810B89F7-154D-47C4-A514-BDED603EFA0C Q30453976-31EEB64A-C42E-4719-8DA8-C170EF2E3A21 Q33410248-DDCA33E5-3AD8-41DC-8006-97E8F8D493A9 Q33924154-7008DACA-3EAA-4A9B-A694-98FBCE448361 Q34078163-575E17B4-F414-4621-97B5-E5C08B3840DA Q34141921-1016989A-08C9-4561-8AC0-5F22E77337AF Q34142507-2B2E2598-3165-41F6-9656-7931068E44FC Q34239134-A6D45CAC-F647-4A69-9E3D-37FAB6B94897 Q34253666-34CEA2B5-53D0-4BFA-82A7-1390AD953AD4 Q34718968-67A61247-27E9-4E6E-835B-D6E0FDECEB5F Q35022274-72613270-B1DC-4A45-8106-4FAE04E6B054 Q35086874-A59D81E4-025A-403F-89D5-9CE927F3C79C Q35196545-88B33FD6-6311-4132-A57D-EEAFA11652D8 Q35694446-3A2C2A8B-4901-46C1-AC5B-F204B959DE63 Q35764760-AAD16A58-5064-49B0-85D4-D8B8530CA141 Q35816412-0CAC257C-DF7E-408E-8052-EBAF8ECC836E Q35823975-CBF6D556-832F-4208-9BA8-6E5EACF87558 Q36137623-2A493BC7-FD79-4026-96F4-446753F411E9 Q36140403-2C0D8F9B-D1CC-4448-8A2B-05E8CCCB7C4D Q36230359-7C764408-0A38-47A0-9307-60614D66F735 Q36231460-B7B3E8B6-66E9-4CD7-B774-8132DCB5FF1A Q36357636-EE6721DB-5D72-4C1C-9FD7-D29CED7A52ED Q36362338-DB7FEB59-374F-4C78-B5EB-51A82A7C7B7B Q36362580-66E24B62-10C8-4722-888C-C3BA1EC7B25E Q36364041-7079BB02-B242-4FFB-98C6-5ACBF264AD24 Q36367622-7F0BDA32-12C6-4875-87A3-229D36615F77 Q36400215-2EE27141-88F6-4678-85F6-718C06E0825B Q36401332-5B000E3A-C81B-4C44-ACB0-24FEAFC04140 Q36599553-499ED676-8164-4CC4-AD03-8BD75DDA5C04 Q36635307-3284C42D-0FC3-4150-8812-24879D77DE4B Q36762461-A8612D80-2D47-4800-82D7-0614FF397329 Q36933256-B0B2ABC6-730F-4E77-BAF0-C0FE37CB9E6E Q37014929-89FE3570-AA14-491C-B609-E3A202A82AF0 Q37088185-FA567717-974D-484A-87BE-966F8DB861F0 Q37242644-6E777122-4D55-422E-9D94-CE8EE01DE979 Q37606380-259D0396-B88D-452D-B190-A238F6F97F0B Q37610298-78877F30-0A41-4E67-A478-47CBF5E6E8B6 Q37783218-3E15DDF7-A825-4369-BE43-147BD3540672 Q37836393-D334AD8E-7AE6-4884-AB74-AEA773319CA4 Q40096435-CDE3FFC6-D164-46A0-A0CF-81BFFBF3E415

P2860

Genetic control of diabetes and insulitis in the nonobese diabetic (NOD) mouse

http://www.wikidata.org/entity/Q36352723

description

1987 nî lūn-bûn

@nan

1987年の論文

@ja

1987年学术文章

@wuu

1987年学术文章

@zh-cn

1987年学术文章

@zh-hans

1987年学术文章

@zh-my

1987年学术文章

@zh-sg

1987年學術文章

@yue

1987年學術文章

@zh

1987年學術文章

@zh-hant

name

Genetic control of diabetes and insulitis in the nonobese diabetic (NOD) mouse

@ast

Genetic control of diabetes and insulitis in the nonobese diabetic (NOD) mouse

@en

type

label

Genetic control of diabetes and insulitis in the nonobese diabetic (NOD) mouse

@ast

Genetic control of diabetes and insulitis in the nonobese diabetic (NOD) mouse

@en

prefLabel

Genetic control of diabetes and insulitis in the nonobese diabetic (NOD) mouse

@ast

Genetic control of diabetes and insulitis in the nonobese diabetic (NOD) mouse

@en

P1433

Q36352723-4A65E255-131D-4C23-B3B0-73C6124D44EF

P1476

Q36352723-B35FEFBD-9384-4B87-B61E-5773A3ECB3E5

P2093

Q36352723-068E665A-800B-4B16-8AEE-7BB9B0BF6F7A

Q36352723-3DF9293A-783B-485D-8019-FE2016883BE9

Q36352723-82408A1B-1D5F-41BF-9831-392C4CCCF3F9

Q36352723-86BCF866-3179-494F-B0DB-53BD75F3E726

Q36352723-B8DE6016-4C6A-4F3F-9DBA-89CC66FDEE80

Q36352723-BFC99C40-673B-45FB-870A-6FC5CDA8E589

Q36352723-C0BBF10D-9E77-4D8A-9473-96F339EDC64E

P2860

Q36352723-12315807-E62D-4716-B009-2FEC004B4ED9

Q36352723-1F96713A-C53E-4DA5-8186-342329038DC7

Q36352723-262AE7E7-5B8C-4153-8658-A2DDF46389F5

Q36352723-3912C965-8F44-4F42-B339-61CB2E7E3F41

Q36352723-59EEC296-0F4C-467A-98E8-565158EACEAB

Q36352723-5AE2CE9D-F9E1-4539-9628-6E41B53C3714

Q36352723-670F8712-6D99-49B3-B5C5-4764B8584AF1

Q36352723-6EB734F2-7434-40D6-A55F-80852BF557FB

Q36352723-85ADAE81-3055-4891-B20B-0C29E2A41C6E

Q36352723-8A898F95-2990-49AB-ADAB-8236D4922168

P304

Q36352723-8888D718-9195-4ED4-A354-F78ABE018D86

P31

Q36352723-88EEBE75-4E95-467B-AF72-8D49FD6ED9AC

P356

Q36352723-66BB9918-D9E9-45DB-8B92-8BAD698BB09F

P407

Q36352723-60B0E342-900A-494B-A664-EF8F61A05833

P433

Q36352723-90CC5E6C-6704-417E-AD0E-A19E4977832E

P478

Q36352723-A3FC393F-E0FD-4402-BD7A-E3DC9EA2987B

P577

Q36352723-68802790-DD35-46B8-B63E-49A2374EC0DE

P5875

Q36352723-A42D83F7-BBFF-4EC7-89A9-423019A4977D

P698

Q36352723-FAD061DA-D340-4983-A992-31EF741F3ABE

P932

Q36352723-69311D13-DEF2-4AEC-801F-D30BF56B68CF

P356

P1433

Journal of Experimental Medicine

P1476

Genetic control of diabetes and insulitis in the nonobese diabetic (NOD) mouse

@en

P2093

B J Miller

http://www.w3.org/2001/XMLSchema#string

L S Wicker

http://www.w3.org/2001/XMLSchema#string

L Z Coker

http://www.w3.org/2001/XMLSchema#string

M C Appel

http://www.w3.org/2001/XMLSchema#string

S E McNally

http://www.w3.org/2001/XMLSchema#string

S Scott

http://www.w3.org/2001/XMLSchema#string

Y Mullen

http://www.w3.org/2001/XMLSchema#string

P2860

Breeding of a non-obese, diabetic strain of mice

Fine specificity of regulatory T cells. II. Suppressor and helper T cells are induced by different regions of hen egg-white lysozyme in a genetically nonresponder mouse strain

Spontaneous diabetes mellitus syndrome in the rat. I. Association with the major histocompatibility complex.

Two genes required for diabetes in BB rats. Evidence from cyclical intercrosses and backcrosses

Specific genomic markers for the HLA-DQ subregion discriminate between DR4+ insulin-dependent diabetes mellitus and DR4+ seropositive juvenile rheumatoid arthritis

Monoclonal antibodies to mouse major histocompatibility complex antigens.

Several mechanisms can account for defective E alpha gene expression in different mouse haplotypes.

A systematic study of HLA class II-beta DNA restriction fragments in insulin-dependent diabetes mellitus.

The immune response genes of the major histocompatibility complex.

The histopathology of the pancreas in type 1 (insulin-dependent) diabetes mellitus: a 25-year review of deaths in patients under 20 years of age in the United Kingdom.

P304

1639-1654

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1084/JEM.165.6.1639

http://www.w3.org/2001/XMLSchema#string

P407

P433

6

http://www.w3.org/2001/XMLSchema#string

P478

165

http://www.w3.org/2001/XMLSchema#string

P577

1987-06-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

274169428

http://www.w3.org/2001/XMLSchema#string

P698

3585250

http://www.w3.org/2001/XMLSchema#string

P932

2188363

http://www.w3.org/2001/XMLSchema#string