Genome-wide pattern of TCF7L2/TCF4 chromatin occupancy in colorectal cancer cells
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Multiple Wnt/ß-catenin responsive enhancers align with the MYC promoter through long-range chromatin loopsWNT/TCF signaling through LEF1 and HOXB9 mediates lung adenocarcinoma metastasisThe pseudoreceptor BMP and activin membrane-bound inhibitor positively modulates Wnt/beta-catenin signalingThe kinase TNIK is an essential activator of Wnt target genesInsights from genomic profiling of transcription factorsWnt/beta-catenin signaling: components, mechanisms, and diseasesA genome-wide screen for beta-catenin binding sites identifies a downstream enhancer element that controls c-Myc gene expressionThe Role of the C-Clamp in Wnt-Related Colorectal CancersTCF/LEF Transcription Factors: An Update from the Internet ResourcesCell-context dependent TCF/LEF expression and function: alternative tales of repression, de-repression and activation potentialsThe combined hyperlipidemia caused by impaired Wnt-LRP6 signaling is reversed by Wnt3a rescueThe cellular prion protein PrPc is a partner of the Wnt pathway in intestinal epithelial cellsThe leukemia-associated Mllt10/Af10-Dot1l are Tcf4/β-catenin coactivators essential for intestinal homeostasisA switch from canonical to noncanonical Wnt signaling mediates drug resistance in colon cancer cellsAlternative splicing of Tcf7l2 transcripts generates protein variants with differential promoter-binding and transcriptional activation properties at Wnt/beta-catenin targetsWnt signaling regulates mitochondrial physiology and insulin sensitivityTargeted repression of AXIN2 and MYC gene expression using designer TALEsThe promoter for intestinal cell kinase is head-to-head with F-Box 9 and contains functional sites for TCF7L2 and FOXA factorsStable S/MAR-based episomal vectors are regulated at the chromatin levelTumor-specific usage of alternative transcription start sites in colorectal cancer identified by genome-wide exon array analysisSole-Search: an integrated analysis program for peak detection and functional annotation using ChIP-seq data.IRS1 regulation by Wnt/beta-catenin signaling and varied contribution of IRS1 to the neoplastic phenotype.A beta-catenin/TCF-coordinated chromatin loop at MYC integrates 5' and 3' Wnt responsive enhancersGenome-wide identification of new Wnt/beta-catenin target genes in the human genome using CART method.Functional screening identifies miRNAs influencing apoptosis and proliferation in colorectal cancer.Long-range enhancers on 8q24 regulate c-Myc.Efficient double fragmentation ChIP-seq provides nucleotide resolution protein-DNA binding profiles.Attenuation of the beta-catenin/TCF4 complex in colorectal cancer cells induces several growth-suppressive microRNAs that target cancer promoting genes.Joint binding of OTX2 and MYC in promotor regions is associated with high gene expression in medulloblastoma.Occupancy classification of position weight matrix-inferred transcription factor binding sites.TCF4 and CDX2, major transcription factors for intestinal function, converge on the same cis-regulatory regionsCATCHprofiles: clustering and alignment tool for ChIP profiles.Genome-wide progesterone receptor binding: cell type-specific and shared mechanisms in T47D breast cancer cells and primary leiomyoma cells.Identification of {beta}-catenin binding regions in colon cancer cells using ChIP-Seq.Complex interplay between β-catenin signalling and Notch effectors in intestinal tumorigenesis.MicroRNA roles in beta-catenin pathway.A unique H3K4me2 profile marks tissue-specific gene regulation.Integration of Hi-C and ChIP-seq data reveals distinct types of chromatin linkagesHepatitis B viral core protein disrupts human host gene expression by binding to promoter regions.Novel β-catenin target genes identified in thalamic neurons encode modulators of neuronal excitability.
P2860
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P2860
Genome-wide pattern of TCF7L2/TCF4 chromatin occupancy in colorectal cancer cells
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Genome-wide pattern of TCF7L2/TCF4 chromatin occupancy in colorectal cancer cells
@ast
Genome-wide pattern of TCF7L2/TCF4 chromatin occupancy in colorectal cancer cells
@en
type
label
Genome-wide pattern of TCF7L2/TCF4 chromatin occupancy in colorectal cancer cells
@ast
Genome-wide pattern of TCF7L2/TCF4 chromatin occupancy in colorectal cancer cells
@en
prefLabel
Genome-wide pattern of TCF7L2/TCF4 chromatin occupancy in colorectal cancer cells
@ast
Genome-wide pattern of TCF7L2/TCF4 chromatin occupancy in colorectal cancer cells
@en
P2093
P2860
P50
P356
P1476
Genome-wide pattern of TCF7L2/TCF4 chromatin occupancy in colorectal cancer cells
@en
P2093
Edwin Cuppen
Evan E Santo
Fiona Nielsen
Hans Clevers
Hendrik G Stunnenberg
Isaäc J Nijman
Laurens G van der Flier
Marc A van Driel
Marc van de Wetering
Pantelis Hatzis
P2860
P304
P356
10.1128/MCB.02175-07
P407
P577
2008-02-11T00:00:00Z