The structural biology of HIV-1: mechanistic and therapeutic insights
about
HIV Genome-Wide Protein Associations: a Review of 30 Years of ResearchG-Quadruplex Forming Oligonucleotides as Anti-HIV AgentsMagic angle spinning NMR of virusesBlind prediction of HIV integrase binding from the SAMPL4 challengeActivities, Crystal Structures, and Molecular Dynamics of Dihydro-1 H -isoindole Derivatives, Inhibitors of HIV-1 IntegraseAllosteric integrase inhibitor potency is determined through the inhibition of HIV-1 particle maturationInsight into the HIV-1 Vif SOCS-box-ElonginBC interactionA New Class of Allosteric HIV-1 Integrase Inhibitors Identified by Crystallographic Fragment Screening of the Catalytic Core DomainElucidation of the early infection machinery of hepatitis B virus by using bio-nanocapsuleCharacteristics of HIV-1 natural drug resistance-associated mutations in former paid blood donors in Henan Province, ChinaStructural Basis for Inhibitor-Induced Aggregation of HIV IntegraseMolecular docking studies of marine diterpenes as inhibitors of wild-type and mutants HIV-1 reverse transcriptase.An integrated map of HIV genome-wide variation from a population perspective.Pseudotype-based neutralization assays for influenza: a systematic analysis.Two M-T hook residues greatly improve the antiviral activity and resistance profile of the HIV-1 fusion inhibitor SC29EK.Efficient Transduction of LEDGF/p75 Mutant Cells by Gain-of-Function HIV-1 Integrase Mutant Viruses.Insights into the structure, correlated motions, and electrostatic properties of two HIV-1 gp120 V3 loops.Crystal structure of an antiviral ankyrin targeting the HIV-1 capsid and molecular modeling of the ankyrin-capsid complex.Structure-based evaluation of non-nucleoside inhibitors with improved potency and solubility that target HIV reverse transcriptase variants.APOBEC3A cytidine deaminase induces RNA editing in monocytes and macrophagesFunctional Constraint Profiling of a Viral Protein Reveals Discordance of Evolutionary Conservation and FunctionalityIdentifying representative drug resistant mutants of HIV.Clinically relevant drug-drug interactions between antiretrovirals and antifungalsFunctional constraints on HIV-1 capsid: their impacts on the viral immune escape potency.6,7-Dihydroxy-1-oxoisoindoline-4-sulfonamide-containing HIV-1 integrase inhibitors.Allosteric inhibition of HIV-1 integrase activity.The Competitive Interplay between Allosteric HIV-1 Integrase Inhibitor BI/D and LEDGF/p75 during the Early Stage of HIV-1 Replication Adversely Affects Inhibitor Potency.Non-natural peptide triazole antagonists of HIV-1 envelope gp120.The Need for Development of New HIV-1 Reverse Transcriptase and Integrase Inhibitors in the Aftermath of Antiviral Drug ResistanceHerb-target interaction network analysis helps to disclose molecular mechanism of traditional Chinese medicine.Investigating the selectivity of metalloenzyme inhibitors.Template-constrained cyclic sulfopeptide HIV-1 entry inhibitorsCellular and Biochemical Mechanisms of the Retroviral Restriction Factor SAMHD1.Multimodal mechanism of action of allosteric HIV-1 integrase inhibitors.Computational and synthetic approaches for developing Lavendustin B derivatives as allosteric inhibitors of HIV-1 integraseSite-specific structural variations accompanying tubular assembly of the HIV-1 capsid protein.Impact of amino acid substitutions in the V2 and C2 regions of human immunodeficiency virus type 1 CRF01_AE envelope glycoprotein gp120 on viral neutralization susceptibility to broadly neutralizing antibodies specific for the CD4 binding site.HIV Drug Resistance and the Advent of Integrase Inhibitors.Integrase strand transfer inhibitors in the management of HIV-positive individuals.LEDGINs, non-catalytic site inhibitors of HIV-1 integrase: a patent review (2006 - 2014).
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P2860
The structural biology of HIV-1: mechanistic and therapeutic insights
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
The structural biology of HIV-1: mechanistic and therapeutic insights
@ast
The structural biology of HIV-1: mechanistic and therapeutic insights
@en
type
label
The structural biology of HIV-1: mechanistic and therapeutic insights
@ast
The structural biology of HIV-1: mechanistic and therapeutic insights
@en
prefLabel
The structural biology of HIV-1: mechanistic and therapeutic insights
@ast
The structural biology of HIV-1: mechanistic and therapeutic insights
@en
P2860
P356
P1476
The structural biology of HIV-1: mechanistic and therapeutic insights
@en
P2093
Alan Engelman
Peter Cherepanov
P2860
P2888
P304
P356
10.1038/NRMICRO2747
P407
P577
2012-03-16T00:00:00Z