Melanoma differentiation associated gene-7/interleukin-24 (mda-7/IL-24): novel gene therapeutic for metastatic melanoma.
about
Developing an effective gene therapy for prostate cancer: New technologies with potential to translate from the laboratory into the clinicTherapy of prostate cancer using a novel cancer terminator virus and a small molecule BH-3 mimeticCisplatin enhances protein kinase R-like endoplasmic reticulum kinase- and CD95-dependent melanoma differentiation-associated gene-7/interleukin-24-induced killing in ovarian carcinoma cellsEradication of therapy-resistant human prostate tumors using an ultrasound-guided site-specific cancer terminator virus delivery approach.Mechanism of autophagy to apoptosis switch triggered in prostate cancer cells by antitumor cytokine melanoma differentiation-associated gene 7/interleukin-24Inhibition of multiple protective signaling pathways and Ad.5/3 delivery enhances mda-7/IL-24 therapy of malignant gliomaPERK-dependent regulation of ceramide synthase 6 and thioredoxin play a key role in mda-7/IL-24-induced killing of primary human glioblastoma multiforme cells.Characterization of the canine mda-7 gene, transcripts and expression patterns.MDA-7/IL-24 as a cancer therapeutic: from bench to bedside.IL-24 gene transfer sensitizes melanoma cells to erlotinib through modulation of the Apaf-1 and Akt signaling pathways.The development of MDA-7/IL-24 as a cancer therapeuticEnhancing mda-7/IL-24 therapy in renal carcinoma cells by inhibiting multiple protective signaling pathways using sorafenib and by Ad.5/3 gene deliveryReversing translational suppression and induction of toxicity in pancreatic cancer cells using a chemoprevention gene therapy approachEnhanced prostate cancer gene transfer and therapy using a novel serotype chimera cancer terminator virus (Ad.5/3-CTV).Myeloid cells migrate in response to IL-24.Gene Therapies for Cancer: Strategies, Challenges and Successes.mda-7/IL-24: a unique member of the IL-10 gene family promoting cancer-targeted toxicity.The Akt signaling pathway: an emerging therapeutic target in malignant melanoma.Suppression of Her2/Neu mammary tumor development in mda-7/IL-24 transgenic miceAutocrine regulation of mda-7/IL-24 mediates cancer-specific apoptosis.Combinatorial strategies based on CRAd-IL24 and CRAd-ING4 virotherapy with anti-angiogenesis treatment for ovarian cancer.Selected approaches for rational drug design and high throughput screening to identify anti-cancer moleculesOncolytic adenoviruses expressing interleukin: a novel antitumour approach.Naturally occurring, tumor-specific, therapeutic proteins.Molecular targets and signaling pathways regulated by interleukin (IL)-24 in mediating its antitumor activities.A review on interleukins: The key manipulators in rheumatoid arthritis.Inhibitory effect of melanoma differentiation associated gene-7/interleukin-24 on invasion in vitro of human melanoma cancer cells.IL-24 sensitizes tumor cells to TLR3-mediated apoptosisA conditionally replicating adenovirus carrying interleukin-24 sensitizes melanoma cells to radiotherapy via apoptosis.A novel conditionally replicating adenoviral vector with dual expression of IL-24 and arresten inserted in E1 and the region between E4 and fiber for improved melanoma therapy.OSU-03012 enhances Ad.7-induced GBM cell killing via ER stress and autophagy and by decreasing expression of mitochondrial protective proteins.Mechanism of in vitro pancreatic cancer cell growth inhibition by melanoma differentiation-associated gene-7/interleukin-24 and perillyl alcohol.Interleukin-24 inhibits osteosarcoma cell migration and invasion via the JNK/c-Jun signaling pathways.The potential of virus-based gene therapies for treatment of metastatic kidney cancer.A cancer terminator virus eradicates both primary and distant human melanomas.Inflammatory Cytokine Pattern Is Sex-Dependent in Mouse Cutaneous Melanoma Experimental Model.Cancer Terminator Viruses (CTV): A Better Solution for Viral-Based Therapy of Cancer.
P2860
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P2860
Melanoma differentiation associated gene-7/interleukin-24 (mda-7/IL-24): novel gene therapeutic for metastatic melanoma.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Melanoma differentiation assoc ...... eutic for metastatic melanoma.
@ast
Melanoma differentiation assoc ...... eutic for metastatic melanoma.
@en
type
label
Melanoma differentiation assoc ...... eutic for metastatic melanoma.
@ast
Melanoma differentiation assoc ...... eutic for metastatic melanoma.
@en
prefLabel
Melanoma differentiation assoc ...... eutic for metastatic melanoma.
@ast
Melanoma differentiation assoc ...... eutic for metastatic melanoma.
@en
P2093
P2860
P1476
Melanoma differentiation assoc ...... eutic for metastatic melanoma.
@en
P2093
Devanand Sarkar
Irina V Lebedeva
John Nemunaitis
Luni Emdad
Moira Sauane
Neil Senzer
Pankaj Gupta
Paul B Fisher
Steven Grant
Zao-zhong Su
P2860
P304
P356
10.1016/J.TAAP.2006.11.021
P577
2006-11-23T00:00:00Z