Insight into the catalytic mechanism of DNA polymerase beta: structures of intermediate complexes
about
DNA polymerase family X: function, structure, and cellular rolesStable complexes formed by HIV-1 reverse transcriptase at distinct positions on the primer-template controlled by binding deoxynucleoside triphosphates or foscarnetIncorporation of non-nucleoside triphosphate analogues opposite to an abasic site by human DNA polymerases beta and lambda.Structures of dNTP Intermediate States during DNA Polymerase Active Site AssemblyHuman DNA Polymerase η Is Pre-Aligned for dNTP Binding and Catalysisβ,γ-CHF- and β,γ-CHCl-dGTP Diastereomers: Synthesis, Discrete 31 P NMR Signatures, and Absolute Configurations of New Stereochemical Probes for DNA PolymerasesStructural Changes in the Hydrophobic Hinge Region Adversely Affect the Activity and Fidelity of the I260Q Mutator DNA Polymerase βOxidant and environmental toxicant-induced effects compromise DNA ligation during base excision DNA repairStructure and mechanism of DNA polymerase βComputer simulations of protein functions: searching for the molecular origin of the replication fidelity of DNA polymerasesA water-mediated and substrate-assisted catalytic mechanism for Sulfolobus solfataricus DNA polymerase IV.Regulation of DNA repair fidelity by molecular checkpoints: "gates" in DNA polymerase beta's substrate selectionRB69 DNA polymerase structure, kinetics, and fidelity.The reopening rate of the fingers domain is a determinant of base selectivity for RB69 DNA polymerase.Effect of A and B metal ion site occupancy on conformational changes in an RB69 DNA polymerase ternary complex.Highly organized but pliant active site of DNA polymerase beta: compensatory mechanisms in mutant enzymes revealed by dynamics simulations and energy analyses.Dependence of DNA polymerase replication rate on external forces: a model based on molecular dynamics simulationsDistinct roles of the active-site Mg2+ ligands, Asp882 and Asp705, of DNA polymerase I (Klenow fragment) during the prechemistry conformational transitions.Direct electrical detection of DNA synthesis.Dynamic mechanism of nick recognition by DNA ligase.Energy analysis of chemistry for correct insertion by DNA polymerase beta.Prechemistry versus preorganization in DNA replication fidelity.High-resolution crystal structure of Z-DNA in complex with Cr(3+) cationsCharacterization of DNA polymerase β from Danio rerio by overexpression in E. coli using the in vivo/in vitro compatible pIVEX plasmid.Expanding the repertoire of DNA polymerase substrates: template-instructed incorporation of non-nucleoside triphosphate analogues by DNA polymerases beta and lambdaDNA replication fidelity.Two proton transfers in the transition state for nucleotidyl transfer catalyzed by RNA- and DNA-dependent RNA and DNA polymerasesDiffering conformational pathways before and after chemistry for insertion of dATP versus dCTP opposite 8-oxoG in DNA polymerase betaMagnesium-cationic dummy atom molecules enhance representation of DNA polymerase beta in molecular dynamics simulations: improved accuracy in studies of structural features and mutational effects.Magnesium-induced assembly of a complete DNA polymerase catalytic complex.Loop II of DNA polymerase beta is important for polymerization activity and fidelity.Metal-induced DNA translocation leads to DNA polymerase conformational activation.Reprint of "Oxidant and environmental toxicant-induced effects compromise DNA ligation during base excision DNA repair".Exploring the role of large conformational changes in the fidelity of DNA polymerase betaPoliovirus RNA-dependent RNA polymerase (3Dpol): kinetic, thermodynamic, and structural analysis of ribonucleotide selection.Poliovirus RNA-dependent RNA polymerase (3Dpol): pre-steady-state kinetic analysis of ribonucleotide incorporation in the presence of Mn2+.Multifactor dimensionality reduction analysis identifies specific nucleotide patterns promoting genetic polymorphisms.Techniques used to study the DNA polymerase reaction pathway.Fluorescent DNA-based enzyme sensors.Why nature really chose phosphate.
P2860
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P2860
Insight into the catalytic mechanism of DNA polymerase beta: structures of intermediate complexes
description
2001 nî lūn-bûn
@nan
2001 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Insight into the catalytic mec ...... ures of intermediate complexes
@ast
Insight into the catalytic mec ...... ures of intermediate complexes
@en
Insight into the catalytic mec ...... ures of intermediate complexes
@nl
type
label
Insight into the catalytic mec ...... ures of intermediate complexes
@ast
Insight into the catalytic mec ...... ures of intermediate complexes
@en
Insight into the catalytic mec ...... ures of intermediate complexes
@nl
prefLabel
Insight into the catalytic mec ...... ures of intermediate complexes
@ast
Insight into the catalytic mec ...... ures of intermediate complexes
@en
Insight into the catalytic mec ...... ures of intermediate complexes
@nl
P2093
P356
P1433
P1476
Insight into the catalytic mec ...... ures of intermediate complexes
@en
P2093
A K Showalter
C A Dunlap
P304
P356
10.1021/BI002176J
P407
P577
2001-05-08T00:00:00Z