Role of brain-derived neurotrophic factor in Huntington's disease.
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Oligonucleotide therapeutic approaches for Huntington diseaseMetabolic dysfunction in Alzheimer's disease and related neurodegenerative disordersA natural antisense transcript at the Huntington's disease repeat locus regulates HTT expressionHuman immunodeficiency virus type 1 alters brain-derived neurotrophic factor processing in neuronsPotential therapeutic effects of neurotrophins for acute and chronic neurological diseasesIron dysregulation in Huntington's diseaseInvolvement of long noncoding RNAs in diseases affecting the central nervous systemMouse models of polyglutamine diseases in therapeutic approaches: review and data table. Part II.Possible involvement of self-defense mechanisms in the preferential vulnerability of the striatum in Huntington's diseaseLaquinimod rescues striatal, cortical and white matter pathology and results in modest behavioural improvements in the YAC128 model of Huntington disease.Transcriptome tomography for brain analysis in the web-accessible anatomical spaceNeurotrophic factors as a therapeutic target for Parkinson's diseaseCyclotraxin-B, the first highly potent and selective TrkB inhibitor, has anxiolytic properties in miceSystemic delivery of recombinant brain derived neurotrophic factor (BDNF) in the R6/2 mouse model of Huntington's diseaseIdentification of BDNF sensitive electrophysiological markers of synaptic activity and their structural correlates in healthy subjects using a genetic approach utilizing the functional BDNF Val66Met polymorphism.Precursor of brain-derived neurotrophic factor (proBDNF) forms a complex with Huntingtin-associated protein-1 (HAP1) and sortilin that modulates proBDNF trafficking, degradation, and processingInhibition of the striatal specific phosphodiesterase PDE10A ameliorates striatal and cortical pathology in R6/2 mouse model of Huntington's diseaseImpaired TrkB receptor signaling underlies corticostriatal dysfunction in Huntington's diseaseMultiple phenotypes in Huntington disease mouse neural stem cells.Up-regulating BDNF with an ampakine rescues synaptic plasticity and memory in Huntington's disease knockin mice.Inactivation of Drosophila Huntingtin affects long-term adult functioning and the pathogenesis of a Huntington's disease model.Localization of BDNF mRNA with the Huntington's disease protein in rat brain.BDNF-TrkB signaling in striatopallidal neurons controls inhibition of locomotor behavior.Short-term striatal gene expression responses to brain-derived neurotrophic factor are dependent on MEK and ERK activation.Expressed Alu repeats as a novel, reliable tool for normalization of real-time quantitative RT-PCR data.Progressive synaptic pathology of motor cortical neurons in a BAC transgenic mouse model of Huntington's disease.Composite primary neuronal high-content screening assay for Huntington's disease incorporating non-cell-autonomous interactions.A small molecule p75NTR ligand normalizes signalling and reduces Huntington's disease phenotypes in R6/2 and BACHD mice.Rescuing the Corticostriatal Synaptic Disconnection in the R6/2 Mouse Model of Huntington's Disease: Exercise, Adenosine Receptors and AmpakinesStriatal Vulnerability in Huntington's Disease: Neuroprotection Versus Neurotoxicity.Neurotoxicity of human immunodeficiency virus-1: viral proteins and axonal transportLaquinimod treatment in the R6/2 mouse model.Differential vulnerability of neurons in Huntington's disease: the role of cell type-specific features.Impaired TrkB-mediated ERK1/2 activation in huntington disease knock-in striatal cells involves reduced p52/p46 Shc expressionBrain-derived neurotrophic factor in patients with Huntington's diseaseIntranasal delivery of neurotrophic factors BDNF, CNTF, EPO, and NT-4 to the CNS.Small molecule BDNF mimetics activate TrkB signaling and prevent neuronal degeneration in rodents.Small-molecule TrkB receptor agonists improve motor function and extend survival in a mouse model of Huntington's diseaseDifferential loss of thalamostriatal and corticostriatal input to striatal projection neuron types prior to overt motor symptoms in the Q140 knock-in mouse model of Huntington's disease.Brief ampakine treatments slow the progression of Huntington's disease phenotypes in R6/2 mice
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P2860
Role of brain-derived neurotrophic factor in Huntington's disease.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Role of brain-derived neurotrophic factor in Huntington's disease.
@ast
Role of brain-derived neurotrophic factor in Huntington's disease.
@en
type
label
Role of brain-derived neurotrophic factor in Huntington's disease.
@ast
Role of brain-derived neurotrophic factor in Huntington's disease.
@en
prefLabel
Role of brain-derived neurotrophic factor in Huntington's disease.
@ast
Role of brain-derived neurotrophic factor in Huntington's disease.
@en
P1476
Role of brain-derived neurotrophic factor in Huntington's disease.
@en
P304
P356
10.1016/J.PNEUROBIO.2007.01.003
P577
2007-02-09T00:00:00Z