Promoter-specific trans activation and repression by human cytomegalovirus immediate-early proteins involves common and unique protein domains.
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Use of differential display analysis to assess the effect of human cytomegalovirus infection on the accumulation of cellular RNAs: induction of interferon-responsive RNAsProteasome-independent disruption of PML oncogenic domains (PODs), but not covalent modification by SUMO-1, is required for human cytomegalovirus immediate-early protein IE1 to inhibit PML-mediated transcriptional repression.Ability of the human cytomegalovirus IE1 protein to modulate sumoylation of PML correlates with its functional activities in transcriptional regulation and infectivity in cultured fibroblast cellsCloning and mutagenesis of a herpesvirus genome as an infectious bacterial artificial chromosomeAutorepression of the human cytomegalovirus major immediate-early promoter/enhancer at late times of infection is mediated by the recruitment of chromatin remodeling enzymes by IE86Prolonged activation of NF-kappaB by human cytomegalovirus promotes efficient viral replication and late gene expressionAntiviral activity of a phosphorothioate oligonucleotide complementary to RNA of the human cytomegalovirus major immediate-early regionOpen reading frame UL26 of human cytomegalovirus encodes a novel tegument protein that contains a strong transcriptional activation domain.A human cytomegalovirus-encoded microRNA regulates expression of multiple viral genes involved in replication.Human cytomegalovirus and human herpesvirus 6 genes that transform and transactivateHuman cytomegalovirus latency-associated protein pORF94 is dispensable for productive and latent infection.Transcriptional regulation of the human cytomegalovirus US11 early gene.Effects of human cytomegalovirus major immediate-early proteins in controlling the cell cycle and inhibiting apoptosis: studies with ts13 cellsThe phosphorylation status of the serine-rich region of the human cytomegalovirus 86-kilodalton major immediate-early protein IE2/IEP86 affects temporal viral gene expression.Transcription factor Sp1 mediates cell-specific trans-activation of the human cytomegalovirus DNA polymerase gene promoter by immediate-early protein IE86 in glioblastoma U373MG cells.Defective growth correlates with reduced accumulation of a viral DNA replication protein after low-multiplicity infection by a human cytomegalovirus ie1 mutant.Persistence and expression of the herpes simplex virus genome in the absence of immediate-early proteins.Phosphorylation of the human cytomegalovirus 86-kilodalton immediate-early protein IE2.Elimination of ie1 significantly attenuates murine cytomegalovirus virulence but does not alter replicative capacity in cell cultureThe human cytomegalovirus major immediate-early distal enhancer region is required for efficient viral replication and immediate-early gene expression.Covalent modification of the transactivator protein IE2-p86 of human cytomegalovirus by conjugation to the ubiquitin-homologous proteins SUMO-1 and hSMT3b.Identification of a boundary domain adjacent to the potent human cytomegalovirus enhancer that represses transcription of the divergent UL127 promoter.The major immediate-early gene ie3 of mouse cytomegalovirus is essential for viral growth.Dominance of virus over host factors in cross-species activation of human cytomegalovirus early gene expression.Reactivation of the human cytomegalovirus major immediate-early regulatory region and viral replication in embryonal NTera2 cells: role of trichostatin A, retinoic acid, and deletion of the 21-base-pair repeats and modulator.Exon 3 of the human cytomegalovirus major immediate-early region is required for efficient viral gene expression and for cellular cyclin modulation.Mouse embryonic stem cells inhibit murine cytomegalovirus infection through a multi-step processRandom, asynchronous, and asymmetric transcriptional activity of enhancer-flanking major immediate-early genes ie1/3 and ie2 during murine cytomegalovirus latency in the lungs.An AP-1 binding site is the predominant cis-acting regulatory element in the 1.2-kilobase early RNA promoter of human cytomegalovirus.Functional properties of the human cytomegalovirus IE86 protein required for transcriptional regulation and virus replicationRequirement of multiple cis-acting elements in the human cytomegalovirus major immediate-early distal enhancer for viral gene expression and replication.Strain variations in single amino acids of the 86-kilodalton human cytomegalovirus major immediate-early protein (IE2) affect its functional and biochemical properties: implications of dynamic protein conformation.The human cytomegalovirus US3 immediate-early protein lacking the putative transmembrane domain regulates gene expression.Absence of IE1 p72 protein function during low-multiplicity infection by human cytomegalovirus results in a broad block to viral delayed-early gene expression.Role of the human cytomegalovirus major immediate-early promoter's 19-base-pair-repeat cyclic AMP-response element in acutely infected cells.Cytomegalovirus immediate early genes prevent the inhibitory effect of cyclosporin A on interleukin 2 gene transcription.Analysis of splice variants of the immediate-early 1 region of human cytomegalovirus.The IE2 60-kilodalton and 40-kilodalton proteins are dispensable for human cytomegalovirus replication but are required for efficient delayed early and late gene expression and production of infectious virus.Analysis and mapping of a family of 3'-coterminal transcripts containing coding sequences for human cytomegalovirus open reading frames UL93 through UL99.Growth kinetics of human cytomegalovirus are altered in monocyte-derived macrophages.
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P2860
Promoter-specific trans activation and repression by human cytomegalovirus immediate-early proteins involves common and unique protein domains.
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
1990年论文
@zh
1990年论文
@zh-cn
name
Promoter-specific trans activa ...... on and unique protein domains.
@ast
Promoter-specific trans activa ...... on and unique protein domains.
@en
type
label
Promoter-specific trans activa ...... on and unique protein domains.
@ast
Promoter-specific trans activa ...... on and unique protein domains.
@en
prefLabel
Promoter-specific trans activa ...... on and unique protein domains.
@ast
Promoter-specific trans activa ...... on and unique protein domains.
@en
P2093
P2860
P1433
P1476
Promoter-specific trans activa ...... on and unique protein domains.
@en
P2093
B P Magrane
J A Nelson
R M Stenberg
S W Barlow
P2860
P304
P407
P577
1990-04-01T00:00:00Z