Expression of v-rel induces mature B-cell lines that reflect the diversity of avian immunoglobulin heavy- and light-chain rearrangements.
about
Myc oncogene-induced genomic instability: DNA palindromes in bursal lymphomagenesis.Multiple mutations contribute to the oncogenicity of the retroviral oncoprotein v-Rel.Retroviral transformation in vitro of chicken T cells expressing either alpha/beta or gamma/delta T cell receptors by reticuloendotheliosis virus strain T.Repression of B-cell linker (BLNK) and B-cell adaptor for phosphoinositide 3-kinase (BCAP) is important for lymphocyte transformation by rel proteins.v-rel Induces ectopic expression of an adhesion molecule, DM-GRASP, during B-lymphoma developmentv-rel induces expression of three avian immunoregulatory surface receptors more efficiently than c-rel.Evolution of the oncogenic potential of v-rel: rel-induced expression of immunoregulatory receptors correlates with tumor development and in vitro transformationOngoing diversification of the rearranged immunoglobulin light-chain gene in a bursal lymphoma cell line.Characterization of a novel promoter insertion in the c-rel locus.Stochastic rearrangement of immunoglobulin variable-region genes in chicken B-cell development.Induction of apoptosis during normal and neoplastic B-cell development in the bursa of Fabricius.A mutant v-rel with increased ability to transform B lymphocytes.The v-rel oncogene promotes malignant T-cell leukemia/lymphoma in transgenic mice.Expression of immunoglobulin genes in the avian embryo bone marrow revealed by retroviral transformation.Duck lymphocytes. VIII. T-lymphoblastoid cell lines from reticuloendotheliosis virus-induced tumours.
P2860
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P2860
Expression of v-rel induces mature B-cell lines that reflect the diversity of avian immunoglobulin heavy- and light-chain rearrangements.
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
1988年论文
@zh
1988年论文
@zh-cn
name
Expression of v-rel induces ma ...... nd light-chain rearrangements.
@en
type
label
Expression of v-rel induces ma ...... nd light-chain rearrangements.
@en
prefLabel
Expression of v-rel induces ma ...... nd light-chain rearrangements.
@en
P2860
P356
P1476
Expression of v-rel induces ma ...... nd light-chain rearrangements.
@en
P2093
E H Humphries
P2860
P304
P356
10.1128/MCB.8.12.5358
P407
P577
1988-12-01T00:00:00Z