A mutation in S6 of Shaker potassium channels decreases the K+ affinity of an ion binding site revealing ion-ion interactions in the pore.
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Amino-terminal determinants of U-type inactivation of voltage-gated K+ channelsTuning the ion selectivity of tetrameric cation channels by changing the number of ion binding sitesNovel insights into K+ selectivity from high-resolution structures of an open K+ channel poreStructural correlates of selectivity and inactivation in potassium channels.Monte Carlo-energy minimization of correolide in the Kv1.3 channel: possible role of potassium ion in ligand-receptor interactions.Batrachotoxin-resistant Na+ channels derived from point mutations in transmembrane segment D4-S6Acceleration of P/C-type inactivation in voltage-gated K(+) channels by methionine oxidation.The link between ion permeation and inactivation gating of Kv4 potassium channels.Slow inactivation in voltage gated potassium channels is insensitive to the binding of pore occluding peptide toxins.Electrostatic influences of charged inner pore residues on the conductance and gating of small conductance Ca2+ activated K+ channels.Origins of ion selectivity in potassium channels from the perspective of channel block.K⁺-dependent selectivity and external Ca²⁺ block of Shab K⁺ channels.Relationship between pore occupancy and gating in BK potassium channels.Voltage dependence of slow inactivation in Shaker potassium channels results from changes in relative K(+) and Na(+) permeabilities.A conducting state with properties of a slow inactivated state in a shaker K(+) channel mutant.Structural similarities between glutamate receptor channels and K(+) channels examined by scanning mutagenesis.Influence of pore residues on permeation properties in the Kv2.1 potassium channel. Evidence for a selective functional interaction of K+ with the outer vestibule.Functional consequences of a decreased potassium affinity in a potassium channel pore. Ion interactions and C-type inactivation.Molecular coupling of S4 to a K(+) channel's slow inactivation gateExtracellular sodium interacts with the HERG channel at an outer pore site.Quinidine interaction with Shab K+ channels: pore block and irreversible collapse of the K+ conductance.Stability of the Shab K+ channel conductance in 0 K+ solutions: the role of the membrane potential.Barium inhibition of the collapse of the Shaker K(+) conductance in zero K(+).A high-Na(+) conduction state during recovery from inactivation in the K(+) channel Kv1.5.Mutations throughout the S6 region of the hKv1.5 channel alter the stability of the activation gate.Na(+) interaction with the pore of Shaker B K(+) channels: zero and low K(+) conditions.Regulation of transient Na+ conductance by intra- and extracellular K+ in the human delayed rectifier K+ channel Kv1.5.Effects on ion permeation with hydrophobic substitutions at a residue in Shaker S6 that interacts with a signature sequence amino acid.A novel current pathway parallel to the central pore in a mutant voltage-gated potassium channel.Allosteric coupling of the inner activation gate to the outer pore of a potassium channel.Preferential binding of K+ ions in the selectivity filter at equilibrium explains high selectivity of K+ channels.A synthetic S6 segment derived from KvAP channel self-assembles, permeabilizes lipid vesicles, and exhibits ion channel activity in bilayer lipid membrane.Second transmembrane domains of ENaC subunits contribute to ion permeation and selectivity.Potassium inhibition of sodium-activated potassium (K(Na)) channels in guinea-pig ventricular myocytes.
P2860
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P2860
A mutation in S6 of Shaker potassium channels decreases the K+ affinity of an ion binding site revealing ion-ion interactions in the pore.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
A mutation in S6 of Shaker pot ...... -ion interactions in the pore.
@en
type
label
A mutation in S6 of Shaker pot ...... -ion interactions in the pore.
@en
prefLabel
A mutation in S6 of Shaker pot ...... -ion interactions in the pore.
@en
P2860
P356
P1476
A mutation in S6 of Shaker pot ...... -ion interactions in the pore.
@en
P2093
E M Ogielska
R W Aldrich
P2860
P304
P356
10.1085/JGP.112.2.243
P577
1998-08-01T00:00:00Z