Therapeutic potential of RhoA/Rho kinase inhibitors in pulmonary hypertension
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Rho-associated kinases in tumorigenesis: re-considering ROCK inhibition for cancer therapyRho-associated kinase signalling and the cancer microenvironment: novel biological implications and therapeutic opportunitiesSelexipag in the treatment of pulmonary arterial hypertension: design, development, and therapyPeptide substrates for Rho-associated kinase 2 (Rho-kinase 2/ROCK2)Activation of glucose-6-phosphate dehydrogenase promotes acute hypoxic pulmonary artery contraction.Endothelial and smooth muscle cell ion channels in pulmonary vasoconstriction and vascular remodelingS1P2 receptor-dependent Rho-kinase activation mediates vasoconstriction in the murine pulmonary circulation induced by sphingosine 1-phosphateCigarette smoke exposure up-regulates endothelin receptor B in human pulmonary artery endothelial cells: molecular and functional consequencesNew perspectives for the treatment of pulmonary hypertensionContribution of Rho-kinase to membrane excitability of murine colonic smooth muscle.Combination of sildenafil and simvastatin ameliorates monocrotaline-induced pulmonary hypertension in rats.Cell-specific dual role of caveolin-1 in pulmonary hypertension.STIM2 Contributes to Enhanced Store-operated Ca Entry in Pulmonary Artery Smooth Muscle Cells from Patients with Idiopathic Pulmonary Arterial Hypertension.Endothelin-1 contributes to increased NFATc3 activation by chronic hypoxia in pulmonary arteries.Pleiotropic effects of statins in distal human pulmonary artery smooth muscle cellsNa(+)/H(+) exchange and hypoxic pulmonary hypertension.The Effects and Mechanism of Atorvastatin on Pulmonary Hypertension Due to Left Heart DiseaseChronic hypoxia does not cause wall thickening of intra-acinar pulmonary supernumerary arteriesVascular remodeling in pulmonary hypertension.Glutathione (GSH) and the GSH synthesis gene Gclm modulate vascular reactivity in mice.In vivo effect of statins on the expression of the HIV co-receptors CCR5 and CXCR4Dynamics of neutrophil extravasation and vascular permeability are uncoupled during aseptic cutaneous wounding.Rho-kinase inhibition alleviates pulmonary hypertension in transgenic mice expressing a dominant-negative type II bone morphogenetic protein receptor gene.MURC deficiency in smooth muscle attenuates pulmonary hypertensionMechanisms of hypoxic pulmonary vasoconstriction and their roles in pulmonary hypertension: new findings for an old problemCyclooxygenase-2 inhibition and hypoxia-induced pulmonary hypertension: effects on pulmonary vascular remodeling and contractilityRosuvastatin ameliorates the development of pulmonary arterial hypertension in the transgenic (mRen2)27 rat.Rescue treatment with a Rho-kinase inhibitor normalizes right ventricular function and reverses remodeling in juvenile rats with chronic pulmonary hypertension.Pulmonary vascular and ventricular dysfunction in the susceptible patient (2015 Grover Conference series).RhoA/Rho-kinase signaling: a therapeutic target in pulmonary hypertension.RhoA/Rho-kinase: pathophysiologic and therapeutic implications in gastrointestinal smooth muscle tone and relaxation.Emerging drugs for pulmonary hypertension.PPARgamma activation: a potential treatment for pulmonary hypertension.Targeting the mevalonate cascade as a new therapeutic approach in heart disease, cancer and pulmonary disease.Regulation of the pulmonary circulation in the fetus and newborn.New insights into the pathogenesis and treatment of idiopathic pulmonary fibrosis.Protein Arginine Methyltransferases (PRMTs): promising targets for the treatment of pulmonary disorders.Reactive oxygen species as therapeutic targets in pulmonary hypertension.Hypoxic pulmonary hypertension of the newborn.Experimental and transgenic models of pulmonary hypertension.
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P2860
Therapeutic potential of RhoA/Rho kinase inhibitors in pulmonary hypertension
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Therapeutic potential of RhoA/Rho kinase inhibitors in pulmonary hypertension
@en
type
label
Therapeutic potential of RhoA/Rho kinase inhibitors in pulmonary hypertension
@en
prefLabel
Therapeutic potential of RhoA/Rho kinase inhibitors in pulmonary hypertension
@en
P2093
P2860
P356
P1476
Therapeutic potential of RhoA/Rho kinase inhibitors in pulmonary hypertension
@en
P2093
P2860
P304
P356
10.1038/BJP.2008.239
P407
P577
2008-06-09T00:00:00Z