DNA repair is crucial for maintaining hematopoietic stem cell function
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Fine-tuning the ubiquitin code at DNA double-strand breaks: deubiquitinating enzymes at workTopBP1 Governs Hematopoietic Stem/Progenitor Cells Survival in Zebrafish Definitive HematopoiesisThe DNA Damage Response: Making It Safe to Play with KnivesImpaired spermatogenesis and elevated spontaneous tumorigenesis in xeroderma pigmentosum group A gene (Xpa)-deficient mice.Total body irradiation causes residual bone marrow injury by induction of persistent oxidative stress in murine hematopoietic stem cells.Accumulation of DNA damage in hematopoietic stem and progenitor cells during human aging.RecA maintains the integrity of chloroplast DNA molecules in ArabidopsisHematopoietic stem cell defects in mice with deficiency of Fancd2 or Usp1.Tight regulation of ubiquitin-mediated DNA damage response by USP3 preserves the functional integrity of hematopoietic stem cells.Genotoxic consequences of endogenous aldehydes on mouse haematopoietic stem cell function.Haematopoietic stem and progenitor cells in rheumatoid arthritisCaspase-9 is required for normal hematopoietic development and protection from alkylator-induced DNA damage in miceCongenital bone marrow failure in DNA-PKcs mutant mice associated with deficiencies in DNA repair.NADPH oxidase inhibition attenuates total body irradiation-induced haematopoietic genomic instabilityA sensitive and quantitative polymerase chain reaction-based cell free in vitro non-homologous end joining assay for hematopoietic stem cells.Bone marrow failure in Fanconi anemia is triggered by an exacerbated p53/p21 DNA damage response that impairs hematopoietic stem and progenitor cells.Cell autonomous and nonautonomous mechanisms drive hematopoietic stem/progenitor cell loss in the absence of DNA repair.A pathogenic dyskerin mutation impairs proliferation and activates a DNA damage response independent of telomere length in mice.Sirt1 ablation promotes stress-induced loss of epigenetic and genomic hematopoietic stem and progenitor cell maintenanceTGF-β Inhibition Rescues Hematopoietic Stem Cell Defects and Bone Marrow Failure in Fanconi Anemia.Parp-2 is required to maintain hematopoiesis following sublethal γ-irradiation in miceTissue-specific accelerated aging in nucleotide excision repair deficiencyRadiosensitivity of cancer-initiating cells and normal stem cells (or what the Heisenberg uncertainly principle has to do with biology)Bcl2 overexpression rescues the hematopoietic stem cell defects in Ku70-deficient mice by restoration of quiescenceSmall-molecule inhibitors of DNA damage-repair pathways: an approach to overcome tumor resistance to alkylating anticancer drugs.Mutant IDH1 Downregulates ATM and Alters DNA Repair and Sensitivity to DNA Damage Independent of TET2.DNA-damage response in hematopoietic stem cells: an evolutionary trade-off between blood regeneration and leukemia suppression.The immune receptor Trem1 cooperates with diminished DNA damage response to induce preleukemic stem cell expansion.NF-κB-dependent DNA damage-signaling differentially regulates DNA double-strand break repair mechanisms in immature and mature human hematopoietic cells.Zika virus infection dysregulates human neural stem cell growth and inhibits differentiation into neuroprogenitor cells.Transcription-associated events affecting genomic integrity.
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DNA repair is crucial for maintaining hematopoietic stem cell function
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 08 January 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
DNA repair is crucial for maintaining hematopoietic stem cell function
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DNA repair is crucial for maintaining hematopoietic stem cell function.
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type
label
DNA repair is crucial for maintaining hematopoietic stem cell function
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DNA repair is crucial for maintaining hematopoietic stem cell function.
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prefLabel
DNA repair is crucial for maintaining hematopoietic stem cell function
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DNA repair is crucial for maintaining hematopoietic stem cell function.
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P2860
P1433
P1476
DNA repair is crucial for maintaining hematopoietic stem cell function
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P2093
Laura J Niedernhofer
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P304
P356
10.1016/J.DNAREP.2007.11.012
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2008-01-08T00:00:00Z