Links between replication and recombination in Saccharomyces cerevisiae: a hypersensitive requirement for homologous recombination in the absence of Rad27 activity.
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Cdk1 targets Srs2 to complete synthesis-dependent strand annealing and to promote recombinational repairDNA replication meets genetic exchange: chromosomal damage and its repair by homologous recombinationHuman Flap Endonuclease Structures, DNA Double-Base Flipping, and a Unified Understanding of the FEN1 SuperfamilyELG1, a yeast gene required for genome stability, forms a complex related to replication factor CRelative contribution of four nucleases, CtIP, Dna2, Exo1 and Mre11, to the initial step of DNA double-strand break repair by homologous recombination in both the chicken DT40 and human TK6 cell linesSubtle alterations in PCNA-partner interactions severely impair DNA replication and repairMutation in Rpa1 results in defective DNA double-strand break repair, chromosomal instability and cancer in miceSaccharomyces cerevisiae Rrm3p DNA helicase promotes genome integrity by preventing replication fork stalling: viability of rrm3 cells requires the intra-S-phase checkpoint and fork restart activitiesRole of RAD52 epistasis group genes in homologous recombination and double-strand break repairRad51 protein controls Rad52-mediated DNA annealing.Rad52/Rad59-dependent recombination as a means to rectify faulty Okazaki fragment processing.High mobility of flap endonuclease 1 and DNA polymerase eta associated with replication foci in mammalian S-phase nucleus.Ku prevents Exo1 and Sgs1-dependent resection of DNA ends in the absence of a functional MRX complex or Sae2The Schizosaccharomyces pombe rad60 gene is essential for repairing double-strand DNA breaks spontaneously occurring during replication and induced by DNA-damaging agents.A new Saccharomyces cerevisiae strain with a mutant Smt3-deconjugating Ulp1 protein is affected in DNA replication and requires Srs2 and homologous recombination for its viability.Mutations in Mre11 phosphoesterase motif I that impair Saccharomyces cerevisiae Mre11-Rad50-Xrs2 complex stability in addition to nuclease activityOverlapping functions of the Saccharomyces cerevisiae Mre11, Exo1 and Rad27 nucleases in DNA metabolismSrs2 overexpression reveals a helicase-independent role at replication forks that requires diverse cell functionsAlleles of the homologous recombination gene, RAD59, identify multiple responses to disrupted DNA replication in Saccharomyces cerevisiaeComplex minisatellite rearrangements generated in the total or partial absence of Rad27/hFEN1 activity occur in a single generation and are Rad51 and Rad52 dependent.Cancer predisposition and hematopoietic failure in Rad50(S/S) mice.A mutant allele of the transcription factor IIH helicase gene, RAD3, promotes loss of heterozygosity in response to a DNA replication defect in Saccharomyces cerevisiae.Molecular characterization of the Schizosaccharomyces pombe nbs1+ gene involved in DNA repair and telomere maintenanceTopoisomerase I-dependent viability loss in saccharomyces cerevisiae mutants defective in both SUMO conjugation and DNA repair.A conserved function for a Caenorhabditis elegans Com1/Sae2/CtIP protein homolog in meiotic recombination.The human F-Box DNA helicase FBH1 faces Saccharomyces cerevisiae Srs2 and postreplication repair pathway roles.Small molecule inhibitors uncover synthetic genetic interactions of human flap endonuclease 1 (FEN1) with DNA damage response genes.Functional interactions between Sae2 and the Mre11 complex.Mrc1 is required for sister chromatid cohesion to aid in recombination repair of spontaneous damage.Molecular characterization of the role of the Schizosaccharomyces pombe nip1+/ctp1+ gene in DNA double-strand break repair in association with the Mre11-Rad50-Nbs1 complex.Pro-recombination Role of Srs2 Protein Requires SUMO (Small Ubiquitin-like Modifier) but Is Independent of PCNA (Proliferating Cell Nuclear Antigen) Interaction.Chronic oxidative DNA damage due to DNA repair defects causes chromosomal instability in Saccharomyces cerevisiae.Saccharomyces cerevisiae flap endonuclease 1 uses flap equilibration to maintain triplet repeat stabilityRad62 protein functionally and physically associates with the smc5/smc6 protein complex and is required for chromosome integrity and recombination repair in fission yeast.Consider the workhorse: Nonhomologous end-joining in budding yeast.Blocking single-stranded transferred DNA conversion to double-stranded intermediates by overexpression of yeast DNA REPLICATION FACTOR A.Functional interplay of the Mre11 nuclease and Ku in the response to replication-associated DNA damage.Multifunctional roles of Saccharomyces cerevisiae Srs2 protein in replication, recombination and repair.Instability of the human minisatellite CEB1 in rad27Delta and dna2-1 replication-deficient yeast cells.A genetic network that suppresses genome rearrangements in Saccharomyces cerevisiae and contains defects in cancers.
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P2860
Links between replication and recombination in Saccharomyces cerevisiae: a hypersensitive requirement for homologous recombination in the absence of Rad27 activity.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on July 2001
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
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name
Links between replication and ...... the absence of Rad27 activity.
@en
Links between replication and ...... the absence of Rad27 activity.
@nl
type
label
Links between replication and ...... the absence of Rad27 activity.
@en
Links between replication and ...... the absence of Rad27 activity.
@nl
prefLabel
Links between replication and ...... the absence of Rad27 activity.
@en
Links between replication and ...... the absence of Rad27 activity.
@nl
P2093
P2860
P356
P1476
Links between replication and ...... the absence of Rad27 activity
@en
P2093
P2860
P304
P356
10.1073/PNAS.121075598
P407
P50
P577
2001-07-01T00:00:00Z