Role of Syk in B-cell development and antigen-receptor signaling
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Latent membrane protein 2A of Epstein-Barr virus binds WW domain E3 protein-ubiquitin ligases that ubiquitinate B-cell tyrosine kinasesBurrowing through the Heterogeneity: Review of Mouse Models of PTCL-NOSB cell receptor signal transduction in the GC is short-circuited by high phosphatase activityB cell antigen receptor signaling and internalization are mutually exclusive events.AUF1 is involved in splenic follicular B cell maintenanceSecreted IgM deficiency leads to increased BCR signaling that results in abnormal splenic B cell development.Therapeutic targeting of Syk in autoimmune diabetesTransition pattern and mechanism of B-lymphocyte precursors in regenerated mouse bone marrow after subtotal body irradiationMultitasking of Ig-alpha and Ig-beta to regulate B cell antigen receptor function.Targeting Syk as a treatment for allergic and autoimmune disorders.A B cell receptor with two Igalpha cytoplasmic domains supports development of mature but anergic B cells.A role for interferon regulatory factor 4 in receptor editing.Monovalent and multivalent ligation of the B cell receptor exhibit differential dependence upon Syk and Src family kinases.In Vivo RNAi screening identifies a leukemia-specific dependence on integrin beta 3 signalingSyk and pTyr'd: Signaling through the B cell antigen receptorRole of the Igh intronic enhancer Eμ in clonal selection at the pre-B to immature B cell transition.T cell immune deficiency in zap70 mutant zebrafishQuantitative immunofluorescence reveals the signature of active B-cell receptor signaling in diffuse large B-cell lymphoma.Depletion of STAT5 blocks TEL-SYK-induced APMF-type leukemia with myelofibrosis and myelodysplasia in mice.Mechanisms of central tolerance for B cells.Critical role for endocytosis in the regulation of signaling by the Kaposi's sarcoma-associated herpesvirus K1 protein.Low and nontoxic inorganic mercury burdens attenuate BCR-mediated signal transduction.Genomic and expression profiling identifies the B-cell associated tyrosine kinase Syk as a possible therapeutic target in mantle cell lymphoma.Characterization of midostaurin as a dual inhibitor of FLT3 and SYK and potentiation of FLT3 inhibition against FLT3-ITD-driven leukemia harboring activated SYK kinase.Genomic Programming of Human Neonatal Dendritic Cells in Congenital Systemic and In Vitro Cytomegalovirus Infection Reveal Plastic and Robust Immune Pathway Biology Responses.Hypermethylation of the spleen tyrosine kinase promoter in T-lineage acute lymphoblastic leukemia.Distinct Expression and Function of FcεRII in Human B Cells and Monocytes.Targeting tumour microenvironment by tyrosine kinase inhibitor.Identification of new dual spleen tyrosine kinase (Syk) and phosphoionositide-3-kinase δ (PI3Kδ) inhibitors using ligand and structure-based integrated ideal pharmacophore models.SYK Inhibition Induces Apoptosis in Germinal Center-Like B Cells by Modulating the Antiapoptotic Protein Myeloid Cell Leukemia-1, Affecting B-Cell Activation and Antibody Production.Evaluation of Antigen-Conjugated Fluorescent Beads to Identify Antigen-Specific B Cells.
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Role of Syk in B-cell development and antigen-receptor signaling
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on February 2000
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
Role of Syk in B-cell development and antigen-receptor signaling
@en
Role of Syk in B-cell development and antigen-receptor signaling.
@nl
type
label
Role of Syk in B-cell development and antigen-receptor signaling
@en
Role of Syk in B-cell development and antigen-receptor signaling.
@nl
prefLabel
Role of Syk in B-cell development and antigen-receptor signaling
@en
Role of Syk in B-cell development and antigen-receptor signaling.
@nl
P2093
P2860
P356
P1476
Role of Syk in B-cell development and antigen-receptor signaling
@en
P2093
C C Goodnow
R J Cornall
P2860
P304
P356
10.1073/PNAS.97.4.1713
P407
P577
2000-02-01T00:00:00Z