Functional basis of protection against age-related macular degeneration conferred by a common polymorphism in complement factor B
about
Complement in age-related macular degeneration: a focus on functionAMD and the alternative complement pathway: genetics and functional implicationsThe complotype: dictating risk for inflammation and infectionAnimal models of age related macular degenerationGenetic variants in the complement system predisposing to age-related macular degeneration: a reviewAlternative complement pathway deficiency ameliorates chronic smoke-induced functional and morphological ocular injuryGenome-wide association study of age-related macular degeneration identifies associated variants in the TNXB-FKBPL-NOTCH4 region of chromosome 6p21.3Complement factor B mutations in atypical hemolytic uremic syndrome-disease-relevant or benign?Genetic variations in complement factors in patients with congenital thrombotic thrombocytopenic purpura with renal insufficiency.Impaired binding of the age-related macular degeneration-associated complement factor H 402H allotype to Bruch's membrane in human retina.Complement system in pathogenesis of AMD: dual player in degeneration and protection of retinal tissue.Complement factor B polymorphism 32W protects against age-related macular degeneration.Common polymorphisms in C3, factor B, and factor H collaborate to determine systemic complement activity and disease riskDense deposit disease.Copy number variation in the complement factor H-related genes and age-related macular degenerationFunctional analysis of a complement polymorphism (rs17611) associated with rheumatoid arthritisAge-Related Macular Degeneration: A Disease of Systemic or Local Complement Dysregulation?Age-related macular degeneration associated polymorphism rs10490924 in ARMS2 results in deficiency of a complement activator.The role of the immune response in age-related macular degenerationGene expression changes in aging retinal microglia: relationship to microglial support functions and regulation of activation.Genetic control of the alternative pathway of complement in humans and age-related macular degenerationRare variants in CFI, C3 and C9 are associated with high risk of advanced age-related macular degeneration.C3 glomerulopathy: a new classification.Genetic factors associated with age-related macular degeneration.CFB/C2 gene polymorphisms and risk of age-related macular degeneration: a systematic review and meta-analysis.The association between complement component 2/complement factor B polymorphisms and age-related macular degeneration: a HuGE review and meta-analysis.Mechanism of inflammation in age-related macular degeneration: an up-to-date on genetic landmarks.Potential Sources and Roles of Adaptive Immunity in Age-Related Macular Degeneration: Shall We Rename AMD into Autoimmune Macular Disease?Complement Polymorphisms in Kidney Transplantation: Critical in Graft Rejection?The disease-protective complement factor H allotypic variant Ile62 shows increased binding affinity for C3b and enhanced cofactor activity.Reduction in ocular complement factor B protein in mice and monkeys by systemic administration of factor B antisense oligonucleotide.Identification of factor H-like protein 1 as the predominant complement regulator in Bruch's membrane: implications for age-related macular degeneration.A Novel Complotype Combination Associates with Age-Related Macular Degeneration and High Complement Activation Levels in vivo.Role of Factor H and Related Proteins in Regulating Complement Activation in the Macula, and Relevance to Age-Related Macular Degeneration.Complement factor B polymorphism and the phenotype of early age-related macular degeneration.Functional and structural characterization of four mouse monoclonal antibodies to complement C3 with potential therapeutic and diagnostic applications.Interaction between Multimeric von Willebrand Factor and Complement: A Fresh Look to the Pathophysiology of Microvascular Thrombosis.Association of specific genetic polymorphisms with age-related macular degeneration in a northern Chinese population.Complement System and Age-Related Macular Degeneration: Implications of Gene-Environment Interaction for Preventive and Personalized Medicine
P2860
Q24635874-388DF0EB-746E-4E69-98C7-80E555AE1F37Q26744106-BC2C62CC-CBE9-4542-B1A6-BACCDE569F55Q26862665-94A8DF9A-7EFF-41DE-ACE8-18BB42BBC6ADQ27004686-2F444ACD-88BB-4CEA-BECF-733FE7D45B39Q27021836-29B7E833-FEBA-47CA-B0C3-EDF9A4AFDFE7Q27311630-8B5DE32B-56A9-49DE-8754-BC28F856B1BAQ29417061-03319CE1-EAB8-4E67-8BEC-8714C7557A7CQ33414109-9F6439A3-E424-4E34-81C8-4BE4DECE1FCEQ33429667-671F5A0F-23C1-4312-8CB2-825CFB85F07BQ34144798-81C0E361-7ED8-4FD0-9838-7C639DFD52C7Q34208123-9DE1F556-D796-434B-9465-B96C2F5325D1Q34882311-D297EDC8-9D17-47D4-8ED8-31E107539E11Q35008396-D4D0CC1D-942C-4872-8D85-7D60CBEEB931Q35124165-F05FE0C1-B1F4-4735-B69B-6587101C9B41Q35166647-2B9D3F39-6EC4-42D6-9E8C-87DDEBE12F34Q35199125-1DE657F3-5EA2-407B-B52C-ADE04ED60BEEQ35750545-2D33EE40-5E24-46D8-B47B-8CDA3149E542Q36249287-CE9B7C2A-368C-4CB2-A1E8-71DA6BBA0A22Q36914129-B7983252-01C4-46A9-A55C-AE7075B69691Q36997157-482C057D-E200-489F-8493-152C3D763D4FQ37471769-94990F05-DB00-4FDB-B09F-8ECBB877C01CQ37515621-83A39254-5CEB-459C-AD26-283E24AC43FFQ37770399-B0EC99F0-2078-4FB2-9DDC-E2929597E0D0Q37901276-4CDE8001-2540-4F79-A32C-DB28AD587ECDQ37996128-26956CA5-8659-4701-9A08-4F0E56CF2D3EQ38032530-5CF1E45E-A656-473C-8858-D1CEA1A6F392Q38173896-9C711771-C1E6-49B9-A5D5-7F67D0936D8FQ38216031-2176E28D-C44D-4B06-9A88-3DE0630118A2Q39093267-E922C598-ED23-4E19-903E-21C5789FDDB8Q39968584-D394F758-5CD8-45EE-99BA-145BEDA09D0BQ41463811-851612CE-8E7C-4DB3-945B-9B69764A99DBQ41705490-A2EDA6C3-8040-4E64-9252-D4F283CD2628Q42119687-EAA23F7D-D374-4AF6-B313-739EBEF1EA5BQ43162540-25A742B9-C304-4773-9C22-8608DC3D32F0Q44489996-7074CDA5-7C86-439E-9405-9ACBAFB52C1EQ46433084-F1D137AC-B446-4A91-873B-4D5F0C51C6ACQ48220242-2BC9E8FF-1F7A-496A-B487-3300D9DBBF24Q48860255-F11AA978-E8B5-4ADE-8119-15AD77D787D6Q58702202-8852AE9C-DE2C-4370-91AF-22A2E9BE336C
P2860
Functional basis of protection against age-related macular degeneration conferred by a common polymorphism in complement factor B
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 02 March 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Functional basis of protection ...... orphism in complement factor B
@en
Functional basis of protection ...... rphism in complement factor B.
@nl
type
label
Functional basis of protection ...... orphism in complement factor B
@en
Functional basis of protection ...... rphism in complement factor B.
@nl
prefLabel
Functional basis of protection ...... orphism in complement factor B
@en
Functional basis of protection ...... rphism in complement factor B.
@nl
P2860
P50
P356
P1476
Functional basis of protection ...... orphism in complement factor B
@en
P2093
Claire L Harris
Tamara Montes
P2860
P304
P356
10.1073/PNAS.0812584106
P407
P577
2009-03-02T00:00:00Z