Airway and lung pathology due to mucosal surface dehydration in {beta}-epithelial Na+ channel-overexpressing mice: role of TNF-{alpha} and IL-4R{alpha} signaling, influence of neonatal development, and limited efficacy of glucocorticoid treatment
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VAMP8 is a vesicle SNARE that regulates mucin secretion in airway goblet cellsRespiratory distress and perinatal lethality in Nedd4-2-deficient miceEndotoxin inhalation alters lung development in neonatal miceChronic alcohol ingestion changes the landscape of the alveolar epitheliumThe ER stress transducer IRE1β is required for airway epithelial mucin productionProline-Glycine-Proline (PGP) and High Mobility Group Box Protein-1 (HMGB1): Potential Mediators of Cystic Fibrosis Airway Inflammation.BPIFB1 (LPLUNC1) is upregulated in cystic fibrosis lung diseaseCorrelation of apical fluid-regulating channel proteins with lung function in human COPD lungsAirway mucus obstruction triggers macrophage activation and matrix metalloproteinase 12-dependent emphysema.Gene expression in whole lung and pulmonary macrophages reflects the dynamic pathology associated with airway surface dehydration.CaMKII is essential for the proasthmatic effects of oxidation.Mucin production during prenatal and postnatal murine lung development.Baseline Goblet Cell Mucin Secretion in the Airways Exceeds Stimulated Secretion over Extended Time Periods, and Is Sensitive to Shear Stress and Intracellular Mucin Stores.Genetically determined heterogeneity of lung disease in a mouse model of airway mucus obstruction.Mucus clearance, MyD88-dependent and MyD88-independent immunity modulate lung susceptibility to spontaneous bacterial infection and inflammationAntiinflammatory and Antimicrobial Effects of Thiocyanate in a Cystic Fibrosis Mouse Model.CFTR, mucins, and mucus obstruction in cystic fibrosis.Non-contact respiration monitoring for in-vivo murine micro computed tomography: characterization and imaging applicationsNeonatal Pulmonary Macrophage Depletion Coupled to Defective Mucus Clearance Increases Susceptibility to Pneumonia and Alters Pulmonary Immune Responses.Loss of Cftr function exacerbates the phenotype of Na(+) hyperabsorption in murine airways.Small molecular modulation of macrophage migration inhibitory factor in the hyperoxia-induced mouse model of bronchopulmonary dysplasia.Reduced mucociliary clearance in old mice is associated with a decrease in Muc5b mucinMucin Agarose Gel Electrophoresis: Western Blotting for High-molecular-weight Glycoproteins.UDP-glucose promotes neutrophil recruitment in the lung.Pharmacological and genetic reappraisals of protease and oxidative stress pathways in a mouse model of obstructive lung diseases.Contribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung diseaseEarly Postnatal Secondhand Smoke Exposure Disrupts Bacterial Clearance and Abolishes Immune Responses in Muco-Obstructive Lung Disease.Airway mucus, inflammation and remodeling: emerging links in the pathogenesis of chronic lung diseases.Nebulized hyaluronan ameliorates lung inflammation in cystic fibrosis mice.Sialic acid-to-urea ratio as a measure of airway surface hydration.Genetic Deletion and Pharmacological Inhibition of PI3K γ Reduces Neutrophilic Airway Inflammation and Lung Damage in Mice with Cystic Fibrosis-Like Lung Disease.Assessment of lung toxicity caused by bleomycin and amiodarone by Tc-99m HMPAO lung scintigraphy in rats.The IL-4 receptor α has a critical role in bone marrow-derived fibroblast activation and renal fibrosis.Serpine2 deficiency results in lung lymphocyte accumulation and bronchus-associated lymphoid tissue formation.Lung disease phenotypes caused by overexpression of combinations of α-, β-, and γ-subunits of the epithelial sodium channel in mouse airways.Cigarette smoke causes acute airway disease and exacerbates chronic obstructive lung disease in neonatal mice.Effect of LysM+ macrophage depletion on lung pathology in mice with chronic bronchitis.
P2860
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P2860
Airway and lung pathology due to mucosal surface dehydration in {beta}-epithelial Na+ channel-overexpressing mice: role of TNF-{alpha} and IL-4R{alpha} signaling, influence of neonatal development, and limited efficacy of glucocorticoid treatment
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on April 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Airway and lung pathology due ...... cy of glucocorticoid treatment
@en
Airway and lung pathology due ...... y of glucocorticoid treatment.
@nl
type
label
Airway and lung pathology due ...... cy of glucocorticoid treatment
@en
Airway and lung pathology due ...... y of glucocorticoid treatment.
@nl
prefLabel
Airway and lung pathology due ...... cy of glucocorticoid treatment
@en
Airway and lung pathology due ...... y of glucocorticoid treatment.
@nl
P2093
P2860
P921
P356
P1476
Airway and lung pathology due ...... cy of glucocorticoid treatment
@en
P2093
Alessandra Livraghi
Barbara R Grubb
Elizabeth J Hudson
John K Sheehan
Kristen J Wilkinson
Marcus A Mall
Richard C Boucher
Scott H Randell
Wanda K O'Neal
P2860
P304
P356
10.4049/JIMMUNOL.0802557
P407
P577
2009-04-01T00:00:00Z