Activation of phosphatidylinositol 3-kinase by epidermal growth factor, basic fibroblast growth factor, and nerve growth factor in PC12 pheochromocytoma cells.
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Class II phosphoinositide 3-kinases are downstream targets of activated polypeptide growth factor receptorsActinin-4, a novel actin-bundling protein associated with cell motility and cancer invasionRecruitment of the class II phosphoinositide 3-kinase C2beta to the epidermal growth factor receptor: role of Grb2Grb2-associated binder-1 mediates phosphatidylinositol 3-kinase activation and the promotion of cell survival by nerve growth factorThe Src homology 2 domain containing inositol 5-phosphatase SHIP2 is recruited to the epidermal growth factor (EGF) receptor and dephosphorylates phosphatidylinositol 3,4,5-trisphosphate in EGF-stimulated COS-7 cellsPhosphorylation of tyrosine 503 in the erythropoietin receptor (EpR) is essential for binding the P85 subunit of phosphatidylinositol (PI) 3-kinase and for EpR-associated PI 3-kinase activityThe inositol polyphosphate 5-phosphatase, PIPP, Is a novel regulator of phosphoinositide 3-kinase-dependent neurite elongation.c-Cbl is inducibly tyrosine-phosphorylated by epidermal growth factor stimulation in fibroblasts, and constitutively tyrosine-phosphorylated and associated with v-Src in v-src-transformed fibroblasts.Mapping of atypical protein kinase C within the nerve growth factor signaling cascade: relationship to differentiation and survival of PC12 cells.Insulin-like growth factors act synergistically with basic fibroblast growth factor and nerve growth factor to promote chromaffin cell proliferation.Ras mediates Src but not epidermal growth factor-receptor tyrosine kinase signaling pathways in GH4 neuroendocrine cells.The phosphatidylinositol 3-kinase alpha is required for DNA synthesis induced by some, but not all, growth factors.Early changes in protein synthesis induced by basic fibroblast growth factor, nerve growth factor, and epidermal growth factor in PC12 pheochromocytoma cells.NGF-stimulated retrograde transport of trkA in the mammalian nervous systemStimulation of C2C12 myoblast growth by basic fibroblast growth factor and insulin-like growth factor 1 can occur via mitogen-activated protein kinase-dependent and -independent pathwaysReceptor tyrosine kinase signaling mechanisms: Devolving TrkA responses with phosphoproteomics.ErbB3 is involved in activation of phosphatidylinositol 3-kinase by epidermal growth factorRegeneration of diabetic axons is enhanced by selective knockdown of the PTEN gene.Targeted approach to metastatic colorectal cancer: what comes beyond epidermal growth factor receptor antibodies and bevacizumab?Differential responses to nerve growth factor and epidermal growth factor in neurite outgrowth of PC12 cells are determined by Rac1 activation systems.Nerve growth factor activation of the extracellular signal-regulated kinase pathway is modulated by Ca(2+) and calmodulin.Mitogenic signals and transforming potential of Nyk, a newly identified neural cell adhesion molecule-related receptor tyrosine kinase.Definition of signals for neuronal differentiation.Variant PC12 cell line that spontaneously differentiates and extends neuritic processes.Androgen receptor protein is down-regulated by basic fibroblast growth factor in prostate cancer cells.Divergence in the anti-apoptotic signalling pathways used by nerve growth factor and basic fibroblast growth factor (bFGF) in PC12 cells: rescue by bFGF involves protein kinase C deltaEffect of nerve growth factor and fibroblast growth factor on PC12 cells: inhibition by orthovanadate.Requirement of phosphatidylinositol 3-kinase activity for translocation of exogenous aFGF to the cytosol and nucleus.A novel role for farnesyl pyrophosphate synthase in fibroblast growth factor-mediated signal transductionPhorbol esters inhibit fibroblast growth factor-2-stimulated fibroblast proliferation by a p38 MAP kinase dependent pathway.Initiation and maintenance of NGF-stimulated neurite outgrowth requires activation of a phosphoinositide 3-kinase.Basic fibroblast growth factor evokes a rapid glutamate release through activation of the MAPK pathway in cultured cortical neurons.Negative regulation of urokinase-type plasminogen activator production through FGF-2-mediated activation of phosphoinositide 3-kinase.Signalling pathways involved in the sensitisation of mouse nociceptive neurones by nerve growth factor.Role of tau phosphorylation by glycogen synthase kinase-3beta in the regulation of organelle transport.Staurosporine causes epidermal growth factor to induce differentiation in PC12 cells via receptor up-regulation.Differential effect of nerve growth factor on dopaminergic neurotoxin-induced apoptosis.Glycogen synthase kinase-3 beta activity is critical for neuronal death caused by inhibiting phosphatidylinositol 3-kinase or Akt but not for death caused by nerve growth factor withdrawal.Induction of phosphatidic acid by fibroblast growth factor in cultured baby hamster kidney fibroblasts.
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P2860
Activation of phosphatidylinositol 3-kinase by epidermal growth factor, basic fibroblast growth factor, and nerve growth factor in PC12 pheochromocytoma cells.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on October 1992
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Activation of phosphatidylinos ...... n PC12 pheochromocytoma cells.
@en
Activation of phosphatidylinos ...... n PC12 pheochromocytoma cells.
@nl
type
label
Activation of phosphatidylinos ...... n PC12 pheochromocytoma cells.
@en
Activation of phosphatidylinos ...... n PC12 pheochromocytoma cells.
@nl
prefLabel
Activation of phosphatidylinos ...... n PC12 pheochromocytoma cells.
@en
Activation of phosphatidylinos ...... n PC12 pheochromocytoma cells.
@nl
P2860
P356
P1476
Activation of phosphatidylinos ...... n PC12 pheochromocytoma cells.
@en
P2093
R A Bradshaw
S Raffioni
P2860
P304
P356
10.1073/PNAS.89.19.9121
P407
P577
1992-10-01T00:00:00Z