Open reading frame P--a herpes simplex virus gene repressed during productive infection encodes a protein that binds a splicing factor and reduces synthesis of viral proteins made from spliced mRNA
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The splicing factor-associated protein, p32, regulates RNA splicing by inhibiting ASF/SF2 RNA binding and phosphorylationHerpes simplex virus 1 regulatory protein ICP22 interacts with a new cell cycle-regulated factor and accumulates in a cell cycle-dependent fashion in infected cells.A novel cellular protein, p60, interacting with both herpes simplex virus 1 regulatory proteins ICP22 and ICP0 is modified in a cell-type-specific manner and Is recruited to the nucleus after infectionHuman p32, interacts with B subunit of the CCAAT-binding factor, CBF/NF-Y, and inhibits CBF-mediated transcription activation in vitroSplicing factor 2-associated protein p32 participates in ribosome biogenesis by regulating the binding of Nop52 and fibrillarin to preribosome particlesThe autophagic inducer smARF interacts with and is stabilized by the mitochondrial p32 proteinInteractions between rubella virus capsid and host protein p32 are important for virus replication.Crystal structure of human p32, a doughnut-shaped acidic mitochondrial matrix proteinDeath, autoantigen modifications, and tolerance.SOCS1 and SOCS3 are targeted by hepatitis C virus core/gC1qR ligation to inhibit T-cell functionStructure of the T. brucei p22 protein, a cytochrome oxidase subunit II (COII) specific RNA editing accessory factorSerine-arginine-rich protein p30 directs alternative splicing of glucocorticoid receptor pre-mRNA to glucocorticoid receptor beta in neutrophilsThe human gC1qR/p32 gene, C1qBP. Genomic organization and promoter analysisDirect binding of hepatitis C virus core to gC1qR on CD4+ and CD8+ T cells leads to impaired activation of Lck and Akt.Herpes simplex virus 1 open reading frames O and P are not necessary for establishment of latent infection in mice.Drosophila TAP/p32 is a core histone chaperone that cooperates with NAP-1, NLP, and nucleophosmin in sperm chromatin remodeling during fertilization.Neither LAT nor open reading frame P mutations increase expression of spliced or intron-containing ICP0 transcripts in mouse ganglia latently infected with herpes simplex virusThe Herpesvirus Saimiri open reading frame 73 gene product interacts with the cellular protein p32.p32 is a novel target for viral protein ICP34.5 of herpes simplex virus type 1 and facilitates viral nuclear egress.Herpes simplex virus type 1 latently infected neurons differentially express latency-associated and ICP0 transcripts.Genetic analysis in Drosophila reveals a role for the mitochondrial protein p32 in synaptic transmissionA viral function represses accumulation of transcripts from productive-cycle genes in mouse ganglia latently infected with herpes simplex virus.A LAT-associated function reduces productive-cycle gene expression during acute infection of murine sensory neurons with herpes simplex virus type 1.Transcription of the derepressed open reading frame P of herpes simplex virus 1 precludes the expression of the antisense gamma(1)34.5 gene and may account for the attenuation of the mutant virusRole of Host Cell p32 in Herpes Simplex Virus 1 De-Envelopment during Viral Nuclear EgressDC-SIGN, C1q, and gC1qR form a trimolecular receptor complex on the surface of monocyte-derived immature dendritic cellsThe product of ORF O located within the domain of herpes simplex virus 1 genome transcribed during latent infection binds to and inhibits in vitro binding of infected cell protein 4 to its cognate DNA site.Identification of the gC1qR sites for the HIV-1 viral envelope protein gp41 and the HCV core protein: Implications in viral-specific pathogenesis and therapy.Alternatively spliced mRNAs predicted to yield frame-shift proteins and stable intron 1 RNAs of the herpes simplex virus 1 regulatory gene alpha 0 accumulate in the cytoplasm of infected cells.The function of herpes simplex virus genes: a primer for genetic engineering of novel vectorsConstruction of a herpes simplex virus type 1 mutant with only a three-nucleotide change in the branchpoint region of the latency-associated transcript (LAT) and the stability of its two-kilobase LAT intron.Rubella virus capsid protein: a small protein with big functions.Global analysis of herpes simplex virus type 1 transcription using an oligonucleotide-based DNA microarray.The genome sequence of herpes simplex virus type 2Herpes simplex virus type 1 latency-associated transcripts suppress viral replication and reduce immediate-early gene mRNA levels in a neuronal cell lineHerpes simplex virus type 1 U(L)34 gene product is required for viral envelopment.Interaction between herpes simplex virus type 1 IE63 protein and cellular protein p32.Molecular aspects of herpes simplex virus I latency, reactivation, and recurrence.
P2860
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P2860
Open reading frame P--a herpes simplex virus gene repressed during productive infection encodes a protein that binds a splicing factor and reduces synthesis of viral proteins made from spliced mRNA
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on September 1996
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Open reading frame P--a herpes ...... roteins made from spliced mRNA
@en
Open reading frame P--a herpes ...... oteins made from spliced mRNA.
@nl
type
label
Open reading frame P--a herpes ...... roteins made from spliced mRNA
@en
Open reading frame P--a herpes ...... oteins made from spliced mRNA.
@nl
prefLabel
Open reading frame P--a herpes ...... roteins made from spliced mRNA
@en
Open reading frame P--a herpes ...... oteins made from spliced mRNA.
@nl
P2860
P356
P1476
Open reading frame P--a herpes ...... roteins made from spliced mRNA
@en
P2093
P2860
P304
10423-10427
P356
10.1073/PNAS.93.19.10423
P407
P577
1996-09-01T00:00:00Z