Identification and characterization of a mitogen-activated S6 kinase. - Wikidata - wikimedia - TriplyDB

Identification and characterization of a mitogen-activated S6 kinase.

Identification and characterization of a mitogen-activated S6 kinase.

http://www.wikidata.org/entity/Q37482357

about

Cloning and expression of two human p70 S6 kinase polypeptides differing only at their amino termini Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinases mTOR: from growth signal integration to cancer, diabetes and ageing Dual requirement for a newly identified phosphorylation site in p70s6k Up-regulation of phosphorylated/activated p70 S6 kinase and its relationship to neurofibrillary pathology in Alzheimer's disease The role and regulation of mTOR in T-lymphocyte function The human histamine H(2) receptor regulates c-jun and c-fos in a differential manner Ribosomal protein S6 phosphorylation and function during late gestation liver development in the rat Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression Cloning of the mitogen-activated S6 kinase from rat liver reveals an enzyme of the second messenger subfamily.A single gene encodes two isoforms of the p70 S6 kinase: activation upon mitogenic stimulation.Differential regulation of S6 phosphorylation by insulin and epidermal growth factor in Swiss mouse 3T3 cells: insulin activation of type 1 phosphatase.mRNA-selective translation induced by FSH in primary Sertoli cells S6 kinase in quiescent Swiss mouse 3T3 cells is activated by phosphorylation in response to serum treatment Identical Mr 70,000 S6 kinase is activated biphasically by epidermal growth factor: a phosphopeptide that characterizes the late phase Insulin activates a 70-kDa S6 kinase through serine/threonine-specific phosphorylation of the enzyme polypeptide.Luteinizing hormone stimulates mammalian target of rapamycin signaling in bovine luteal cells via pathways independent of AKT and mitogen-activated protein kinase: modulation of glycogen synthase kinase 3 and AMP-activated protein kinase Molecular structure of a major insulin/mitogen-activated 70-kDa S6 protein kinase.Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase.Abnormal regulation of ribosomal protein S6 kinase by insulin in skeletal muscle of insulin-resistant humans.Identification and early activation of a Xenopus laevis p70s6k following progesterone-induced meiotic maturation.The complexes of mammalian target of rapamycin.The modular phosphorylation and activation of p70s6k.Mechanical stimulation induces mTOR signaling via an ERK-independent mechanism: implications for a direct activation of mTOR by phosphatidic acid.Ciliary transport regulates PDGF-AA/αα signaling via elevated mammalian target of rapamycin signaling and diminished PP2A activity.Targeted disruption of p70(s6k) defines its role in protein synthesis and rapamycin sensitivity.Development of monoclonal antibodies specific to ribosomal protein S6 kinase 2.Dissociation of inositol trisphosphate from diacylglycerol production in Rous sarcoma virus-transformed fibroblasts The role of S6K1 in ER-positive breast cancer.Epidermal growth factor (EGF) stimulates association and kinase activity of Raf-1 with the EGF receptor.Regulation of pp90rsk phosphorylation and S6 phosphotransferase activity in Swiss 3T3 cells by growth factor-, phorbol ester-, and cyclic AMP-mediated signal transduction.Identification of mitogen-responsive ribosomal protein S6 kinase pp90rsk, a homolog of Xenopus S6 kinase II, in chicken embryo fibroblasts Two distinct enzymes contribute to biphasic S6 phosphorylation in serum-stimulated chicken embryo fibroblasts Identification of Xenopus S6 protein kinase homologs (pp90rsk) in somatic cells: phosphorylation and activation during initiation of cell proliferation.A Novel Mechanism of PPARgamma Regulation of TGFbeta1: Implication in Cancer Biology Sequence and expression of chicken and mouse rsk: homologs of Xenopus laevis ribosomal S6 kinase Polyomavirus middle T antigen induces ribosomal protein S6 phosphorylation through pp60c-src-dependent and -independent pathways.Tuberous sclerosis complex, implication from a rare genetic disease to common cancer treatment.Activation of p70s6k is associated with phosphorylation of four clustered sites displaying Ser/Thr-Pro motifs mTORC1 phosphorylation sites encode their sensitivity to starvation and rapamycin

P2860

Q24311546-BD7D628E-456F-4279-BD1F-DBE2C902CD24 Q24599204-A7C07618-6073-44F6-911F-E72A71263F3A Q24633662-A6B2EE44-E4A9-4498-9C6E-9059A3C90057 Q24644595-DF7FEA23-6E6B-4A07-99DD-A77511E384DD Q24685592-311ED629-24D0-4C40-811E-41DA5DD6C177 Q26830161-520E62C6-A72F-4760-A1CD-D78789206640 Q28145670-B806FB4B-D8C8-4571-9C2E-588291556643 Q28568255-CC090BE5-2734-4E45-8764-419BCA9F7515 Q29617473-BF397614-22DD-4752-8984-3C4958A0D8AB Q30824759-052CC0CD-416B-4DB7-969E-EEA57BDAD650 Q30846613-F2701AF1-5E88-4818-B507-44FABFEF9B7A Q33584931-2A8775F5-92D7-4A23-9D03-9A3B74545292 Q33636672-C9D3B402-FAC0-4735-894E-CF8B2B413D8C Q33650875-35B3CA01-96C1-437C-9596-E0D34DA8355A Q33788073-6AE592BF-B39D-43B5-9346-DD97BBC9C18B Q33841430-234388E0-387D-463B-8E39-A5DD80D7C207 Q33874422-952467E1-73DE-404D-97A1-445F9E7C2EA0 Q33877880-06354DAA-6EB4-49D0-B467-78EEC9D8C269 Q33890035-8EC2BFFE-85CE-4D76-8B3D-F66D2BB86439 Q33890133-EC7E45AD-72D3-46F1-B004-E59E31957248 Q33937723-4809471F-8BE5-4205-A482-223EEE170680 Q34116818-E0260340-3EC6-48BD-A70E-5C51A4D722FE Q34434557-0907BCFC-A7DE-4458-9DC6-373074777D61 Q34450669-1E3A8CF6-B448-4980-8758-FA5C6889F192 Q34960781-C7406340-72C0-4B1F-8C39-6CD6BE95D001 Q36063511-9057DCB3-46C1-446D-95CC-753E65597451 Q36168887-2FB7F58F-167D-47C7-B170-4B8BC221F985 Q36220044-4CDD706E-2A8F-4B59-AE38-A5CBC5FEC09D Q36304094-19C6D820-BC9D-4EC8-BD42-3872D105E32D Q36684473-D09E62E6-3E3B-4C5E-BF15-73939FCDFD2F Q36687724-099099B9-2950-405C-B487-45925A9D2002 Q36709337-C43665D2-4A6A-4AF1-BC34-9B96A6A17B39 Q36710538-DBD4A25E-6797-4723-B8B9-D0097A706446 Q36711986-FF493462-7A92-4064-99E4-732E57FB65E2 Q36743890-FB05A5AF-E1E0-4BDC-80EB-CF0384DE3D8E Q36760407-A0ED71F4-6F1F-4C2C-877D-F7633723EEDF Q36789817-479FE1C0-9F0F-42CB-85F1-BBCBC0D198D4 Q37134137-94D23DAF-6A95-461A-A6CA-0EC978511C3B Q37143272-63D0413E-F023-440D-82A6-7AF05CD7580A Q37166913-8A59C2F7-D44A-4804-A3F8-D961C5384B97

P2860

Identification and characterization of a mitogen-activated S6 kinase.

http://www.wikidata.org/entity/Q37482357

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on January 1988

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Identification and characterization of a mitogen-activated S6 kinase.

@en

Identification and characterization of a mitogen-activated S6 kinase.

@nl

type

label

Identification and characterization of a mitogen-activated S6 kinase.

@en

Identification and characterization of a mitogen-activated S6 kinase.

@nl

prefLabel

Identification and characterization of a mitogen-activated S6 kinase.

@en

Identification and characterization of a mitogen-activated S6 kinase.

@nl

P1433

Q37482357-1D140F34-6771-47D7-A28E-F72599DD751A

P1476

Q37482357-7F7421BB-E593-409C-89B0-D14E52EEF79C

P2093

Q37482357-73E7A45A-8EC7-418C-BA74-FCC27DA9596B

Q37482357-9612B5C8-2D84-468A-9944-AB499B915C06

Q37482357-ABCD84FA-4D83-4CDF-BC77-F70A324215A9

Q37482357-AD5D8928-198D-41A4-9A2C-2DE0359C698E

P2860

Q37482357-0072EE3B-13DF-4B23-B669-E75561A3215D

Q37482357-05B1BA06-0774-4839-B7EC-42EDA63ED264

Q37482357-0C05B902-54E7-4734-AB1A-7A7CA0212145

Q37482357-24C523F1-4C72-4436-93E7-560C4FDB37A6

Q37482357-26B23BCB-7B99-49D2-AA6D-BB8EE6D55FF5

Q37482357-2F1923D1-29F3-4109-ADFB-3FE59F0BC905

Q37482357-340D1824-069C-419E-8482-F423C6E6D343

Q37482357-35078329-5BBC-4162-95E1-7C8ACF6F62A1

Q37482357-5521D4BB-03ED-4925-AB73-049E05C5F5C7

Q37482357-79B7D4DF-ECDA-44EF-A242-650F244431AE

P304

Q37482357-CF642FB2-D0CA-40C0-9305-58774AA5AF2A

P31

Q37482357-74A2D026-0E14-4696-92BA-A0E0E0D728F8

P356

Q37482357-3F26DD7C-2607-4591-9A21-94DF90F0BDC4

P407

Q37482357-5EEBC0CB-4226-4854-9931-010B1385C48D

P433

Q37482357-455F79A7-186E-42DE-AA49-3581B4133CB6

P478

Q37482357-29283674-E506-4F5E-A26E-F8BE91C1D256

P577

Q37482357-8D05F07E-80D6-4007-9645-CCBB722C989D

P5875

Q37482357-1659909A-0C18-4860-BC6D-7A00FCEB8080

P698

Q37482357-22DDAC7E-F367-4BFB-829B-77BD22D1155C

P932

Q37482357-4952ED33-B56F-41D5-AA33-FD29C3D0F5E6

P356

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Identification and characterization of a mitogen-activated S6 kinase.

@en

P2093

Ballou LM

http://www.w3.org/2001/XMLSchema#string

Jenö P

http://www.w3.org/2001/XMLSchema#string

Novak-Hofer I

http://www.w3.org/2001/XMLSchema#string

Thomas G

http://www.w3.org/2001/XMLSchema#string

P2860

Phosphorylation of ribosomal protein S6 in avian sarcoma virus-transformed chicken embryo fibroblasts.

Stimulation of ribosomal protein S6 kinase activity by pp60v-src or by serum: dissociation from phorbol ester-stimulated activity

Increased phosphorylation of ribosomal protein S6 during meiotic maturation of Xenopus oocytes

Multiple phosphorylation of ribosomal protein S6 during transition of quiescent 3T3 cells into early G1, and cellular compartmentalization of the phosphate donor.

Fibroblast growth factor treatment of Swiss 3T3 cells activates a subunit S6 kinase that phosphorylates a synthetic peptide substrate.

Phorbol esters, phospholipase C, and growth factors rapidly stimulate the phosphorylation of a Mr 80,000 protein in intact quiescent 3T3 cells.

Purified rat brain calcium- and phospholipid-dependent protein kinase phosphorylates ribosomal protein S6.

Activation of S6 kinase activity in 3T3-L1 cells by insulin and phorbol ester.

Regulation of a ribosomal protein S6 kinase activity by the Rous sarcoma virus transforming protein, serum, or phorbol ester.

Ordered phosphorylation of 40S ribosomal protein S6 after serum stimulation of quiescent 3T3 cells.

P304

406-410

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.85.2.406

http://www.w3.org/2001/XMLSchema#string

P407

P433

2

http://www.w3.org/2001/XMLSchema#string

P478

85

http://www.w3.org/2001/XMLSchema#string

P577

1988-01-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

19897875

http://www.w3.org/2001/XMLSchema#string

P698

3257566

http://www.w3.org/2001/XMLSchema#string

P932

279557

http://www.w3.org/2001/XMLSchema#string