Activated Ras signals differentiation and expansion of CD4+8+ thymocytes.
about
Activation of CD4 T cells by Raf-independent effectors of RasOncogenic Kras initiates leukemia in hematopoietic stem cellsLck SH3 domain function is required for T-cell receptor signals regulating thymocyte development.Microarray analysis distinguishes differential gene expression patterns from large and small colony Thymidine kinase mutants of L5178Y mouse lymphoma cellsPak2 is required for actin cytoskeleton remodeling, TCR signaling, and normal thymocyte development and maturation.The GTPase Rho has a critical regulatory role in thymus development.Conference highlight: do T cells care about the mitogen-activated protein kinase signalling pathways?Signal transduction by MAP kinases in T lymphocytes.Deregulated expression of RasGRP1 initiates thymic lymphomagenesis independently of T-cell receptors.Transgenic analysis of thymocyte signal transduction.Allelic exclusion and differentiation by protein kinase C-mediated signals in immature thymocytes.Fli-1 overexpression in hematopoietic progenitors deregulates T cell development and induces pre-T cell lymphoblastic leukaemia/lymphoma.Thymic selection revisited: how essential is it?Regulation and Function of the RasGRP Family of Ras Activators in Blood CellsGTPases and T cell activation.Targeted Sos1 deletion reveals its critical role in early T-cell development.Overexpression of RhoH Permits to Bypass the Pre-TCR Checkpoint.Activated Ras signals developmental progression of recombinase-activating gene (RAG)-deficient pro-B lymphocytes.Deconstructing Ras signaling in the thymusDifferential synergy of Notch and T cell receptor signaling determines alphabeta versus gammadelta lineage fate.Vav1/2/3-null mice define an essential role for Vav family proteins in lymphocyte development and activation but a differential requirement in MAPK signaling in T and B cells.Allelic exclusion of the T cell receptor beta locus requires the SH2 domain-containing leukocyte protein (SLP)-76 adaptor protein.The JNK pathway regulates the In vivo deletion of immature CD4(+)CD8(+) thymocytesRAG2 is regulated differentially in B and T cells by elements 5' of the promoter.c-Myc enhances protein synthesis and cell size during B lymphocyte development.Selective regulation of TCR signaling pathways by the CD45 protein tyrosine phosphatase during thymocyte development.Role of Ras/Raf/MEK/ERK signaling in physiological hematopoiesis and leukemia development.Two distinct steps during thymocyte maturation from CD4-CD8- to CD4+CD8+ distinguished in the early growth response (Egr)-1 transgenic mice with a recombinase-activating gene-deficient background.Interaction of Ras with p110γ is required for thymic β-selection in the mouse.Combinatorial effect of T-cell receptor ligation and CD45 isoform expression on the signaling contribution of the small GTPases Ras and Rap1.p21 Ras/impedes mitogenic signal propagation regulates cytokine production and migration in CD4 T cells.Modulation of the immune system by Listeria monocytogenes-mediated gene transfer into mammalian cells.Elevated expression of the CD4 receptor and cell cycle arrest are induced in Jurkat cells by treatment with the novel cyclic dinucleotide 3',5'-cyclic diguanylic acid.Role for Ets-2(Thr-72) transcription factor in stage-specific thymocyte development and survivalContributions of the T cell receptor-associated CD3gamma-ITAM to thymocyte selectionExtracellular signal-regulated kinase (ERK) activation by the pre-T cell receptor in developing thymocytes in vivo.Distinct signals mediate maturation and allelic exclusion in lymphocyte progenitors.A two-step model of T cell subset commitment: antigen-independent commitment of T cells before encountering nominal antigen during pathogenic infections.Evidence implicating Gfi-1 and Pim-1 in pre-T-cell differentiation steps associated with beta-selectionT-cell fate.
P2860
Q24675067-762832B8-9DB5-4510-AF51-C3A41D66C3F2Q27331698-0D1546F6-5445-41EE-BDD9-6420CB4B039DQ30159670-8C398623-37DE-40E6-ADB3-CE05F52F87DFQ33264212-2DBEBD06-A9CE-4B0F-9B17-32D29C5BE670Q33597132-96B1EB75-4049-4545-B38C-30F830595940Q33886532-DCBE99F0-7B5F-46CD-BCA0-2AD589B04677Q33890366-0D76DEDF-5E56-4DAC-A6D4-B0D5D4BFCB1DQ33951021-7F87902F-0FAB-4FE5-918B-165A5E757824Q34411416-08E08824-7F30-498B-8BEE-FEDE72F4580EQ34572219-E71CD4D9-B23F-4F23-B713-E170B2469F51Q34621439-98481E8B-20BD-46BF-8745-D96592E7E0B3Q34717152-697FD528-2D90-4C42-93FF-05830DBAE388Q35076679-18CC6341-5965-4424-B726-801CF39AF160Q35083742-482A9943-CDDC-4B0D-A1C8-362F6BD263F7Q35096692-EE09C987-9D66-4B49-8890-684D431596ACQ35134263-623ABE26-8AF4-4091-9279-48A60C1AF67DQ35787751-85CF2644-0C44-4A5B-9C04-55B7F75B97E0Q35834585-517BA551-6457-4A5D-96F7-14F3B3BC674BQ36155051-8AE512CE-25AC-44DD-945B-B0D63C018426Q36228639-2B13E1CE-75D6-4A61-882E-A13548799B5FQ36371509-59CD5A6F-8ADE-49B1-A3BC-47D5A01481C5Q36375439-589777F1-5871-4F8E-8CEB-86FDD4322408Q36401296-77E5F13A-0090-4649-B4D7-69985D0AA07CQ36553008-F362D0D9-B7A6-4C43-A4AA-D836B0D5DBE2Q36668198-7BE445A5-C859-4978-8200-04B03A487FFAQ37166168-78031A8D-48D8-4B19-BF43-3BB6269E32A3Q37822317-9F13E7E6-08CC-4A6B-A474-124694A6D026Q38343088-D046A61C-7276-4E1E-8FFB-B8F8EC217646Q38786279-8D455927-B400-4492-87F6-B8120B2A5B81Q39456844-FF8D1979-B9FE-4B54-8192-A5C3E2EFEE38Q39968515-BB4699E0-385C-4149-8AD4-80EA637FFDDFQ40515027-55C1BBC7-0F50-465D-A093-DB368243761CQ40971124-692ED8EA-525C-4E27-81D7-1C3AEAFCE29BQ41479119-7D9E3D6A-657F-4938-92BE-E0146A8BAA87Q41837728-A56968EC-669C-47B8-9F33-B19078F69D56Q41838088-B3C3CD93-B5CE-4350-AAF8-A617298FEAA3Q42321307-A0C65589-42F6-48B8-B41D-1E96BBDDD1F0Q42521916-4659804C-7EF2-4EDA-95F8-5CE32AFF144BQ42654229-A2FA38FC-28F2-4907-9936-9DB36298E437Q46127351-62B2B3F5-1780-4BF6-BAB5-9E4DF3ABC0A4
P2860
Activated Ras signals differentiation and expansion of CD4+8+ thymocytes.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 1996
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Activated Ras signals differentiation and expansion of CD4+8+ thymocytes.
@en
Activated Ras signals differentiation and expansion of CD4+8+ thymocytes.
@nl
type
label
Activated Ras signals differentiation and expansion of CD4+8+ thymocytes.
@en
Activated Ras signals differentiation and expansion of CD4+8+ thymocytes.
@nl
prefLabel
Activated Ras signals differentiation and expansion of CD4+8+ thymocytes.
@en
Activated Ras signals differentiation and expansion of CD4+8+ thymocytes.
@nl
P2093
P2860
P356
P1476
Activated Ras signals differentiation and expansion of CD4+8+ thymocytes.
@en
P2093
P2860
P304
P356
10.1073/PNAS.93.10.4683
P407
P577
1996-05-01T00:00:00Z