Pseudokinases-remnants of evolution or key allosteric regulators?
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Mitochondrial ADCK3 employs an atypical protein kinase-like fold to enable coenzyme Q biosynthesisA secretory kinase complex regulates extracellular protein phosphorylationComplexity in KSR function revealed by Raf inhibitor and KSR structure studiesILK: a pseudokinase in the center stage of cell-matrix adhesion and signalingThe polymorphic pseudokinase ROP5 controls virulence in Toxoplasma gondii by regulating the active kinase ROP18Cerebellar Ataxia and Coenzyme Q Deficiency through Loss of Unorthodox Kinase ActivityStructural and functional characterization of KEOPS dimerization by Pcc1 and its role in t6A biosynthesisA Drosophila-centric view of protein tyrosine phosphatasesAllosteric activation of trypanosomatid deoxyhypusine synthase by a catalytically dead paralogBiochemistry. KSR plays CRAF-tyThe Tribbles 2 (TRB2) pseudokinase binds to ATP and autophosphorylates in a metal-independent mannerTyrosine Kinase 2-mediated Signal Transduction in T Lymphocytes Is Blocked by Pharmacological Stabilization of Its Pseudokinase Domain.Structure of Fam20A reveals a pseudokinase featuring a unique disulfide pattern and inverted ATP-bindingA meta-analysis of lung cancer gene expression identifies PTK7 as a survival gene in lung adenocarcinomaThe Plasmodium falciparum pseudoprotease SERA5 regulates the kinetics and efficiency of malaria parasite egress from host erythrocytes.Modulation of innate immunity by Toxoplasma gondii virulence effectors.A novel protein kinase-like domain in a selenoprotein, widespread in the tree of life.Receptor tyrosine kinases with intracellular pseudokinase domainsA robust methodology to subclassify pseudokinases based on their nucleotide-binding properties.Loss of TRB3 alters dynamics of MLK3-JNK signaling and inhibits cytokine-activated pancreatic beta cell death.Kinase drug discovery--what's next in the field?Tribbles in the 21st Century: The Evolving Roles of Tribbles Pseudokinases in Biology and Disease.Structural and evolutionary adaptation of rhoptry kinases and pseudokinases, a family of coccidian virulence factorsA fully human inhibitory monoclonal antibody to the Wnt receptor RYKAn atypical kinase under balancing selection confers broad-spectrum disease resistance in Arabidopsis.Biochemical, proteomic, structural, and thermodynamic characterizations of integrin-linked kinase (ILK): cross-validation of the pseudokinase.Pseudokinases from a structural perspectiveThe pseudokinase domain of JAK2 is a dual-specificity protein kinase that negatively regulates cytokine signaling.The pseudokinase SgK223 promotes invasion of pancreatic ductal epithelial cells through JAK1/Stat3 signaling.Toxoplasma and Plasmodium protein kinases: roles in invasion and host cell remodelling.Kinome-wide decoding of network-attacking mutations rewiring cancer signaling.Structural and Functional Characterization of the JH2 Pseudokinase Domain of JAK Family Tyrosine Kinase 2 (TYK2).Regulation of Clostridium difficile spore germination by the CspA pseudoprotease domainComparative analysis of the human and zebrafish kinomes: focus on the development of kinase inhibitors.Mammalian tribbles homologs at the crossroads of endoplasmic reticulum stress and Mammalian target of rapamycin pathways.Toxoplasma GRA7 effector increases turnover of immunity-related GTPases and contributes to acute virulence in the mouse.Activation of protein kinase PKR requires dimerization-induced cis-phosphorylation within the activation loop.The receptor-like pseudokinase MRH1 interacts with the voltage-gated potassium channel AKT2.Insights into the Structure, Function, and Ion-Mediated Signaling Pathways Transduced by Plant Integrin-Linked Kinases.Serine/threonine kinases and E2-ubiquitin conjugating enzymes in Planctomycetes: unexpected findings.
P2860
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P2860
Pseudokinases-remnants of evolution or key allosteric regulators?
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
Pseudokinases-remnants of evolution or key allosteric regulators?
@en
Pseudokinases-remnants of evolution or key allosteric regulators?
@en-gb
Pseudokinases-remnants of evolution or key allosteric regulators?
@nl
type
label
Pseudokinases-remnants of evolution or key allosteric regulators?
@en
Pseudokinases-remnants of evolution or key allosteric regulators?
@en-gb
Pseudokinases-remnants of evolution or key allosteric regulators?
@nl
prefLabel
Pseudokinases-remnants of evolution or key allosteric regulators?
@en
Pseudokinases-remnants of evolution or key allosteric regulators?
@en-gb
Pseudokinases-remnants of evolution or key allosteric regulators?
@nl
P2860
P1476
Pseudokinases-remnants of evolution or key allosteric regulators?
@en
P2093
Daan M F van Aalten
P2860
P304
P356
10.1016/J.SBI.2010.10.001
P577
2010-11-10T00:00:00Z