Regulation of the sequence-specific DNA binding function of p53 by protein kinase C and protein phosphatases.
about
Repression of p53-mediated transcription by MDM2: a dual mechanismKu86 autoantigen related protein-1 transcription initiates from a CpG island and is induced by p53 through a nearby p53 response elementA peptide that binds and stabilizes p53 core domain: chaperone strategy for rescue of oncogenic mutantsExpression of the papillomavirus E2 protein in HeLa cells leads to apoptosisProtein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signallingp53 is phosphorylated by CDK7-cyclin H in a p36MAT1-dependent mannerInteraction with p53 enhances binding of cisplatin-modified DNA by high mobility group 1 proteinThe double-stranded RNA activated protein kinase PKR physically associates with the tumor suppressor p53 protein and phosphorylates human p53 on serine 392 in vitroThe processing of Holliday junctions by BLM and WRN helicases is regulated by p53Poly(ADP-ribose) binds to specific domains of p53 and alters its DNA binding functionsModification of two distinct COOH-terminal domains is required for murine p53 activation by bacterial Hsp70Receptor protein tyrosine kinase DDR is up-regulated by p53 proteinp53-mediated regulation of proliferating cell nuclear antigen expression in cells exposed to ionizing radiationCdk5 phosphorylates p53 and regulates its activityDNA damage activates p53 through a phosphorylation-acetylation cascadeFunction of p73, not of p53, is inhibited by the physical interaction with RACK1 and its inhibitory effect is counteracted by pRB.Staf50 is a novel p53 target gene conferring reduced clonogenic growth of leukemic U-937 cells.Degradation of phosphorylated p53 by viral protein-ECS E3 ligase complex.Molecular interaction map of the mammalian cell cycle control and DNA repair systems.USP7/HAUSP promotes the sequence-specific DNA binding activity of p53.Activation of the Epstein-Barr virus transcription factor BZLF1 by 12-O-tetradecanoylphorbol-13-acetate-induced phosphorylation.Mechanisms of switching on p53: a role for covalent modification?E2F1 has both oncogenic and tumor-suppressive properties in a transgenic modelTumor suppressor p53 is required to modulate BRCA1 expression.Jun NH2-terminal kinase phosphorylation of p53 on Thr-81 is important for p53 stabilization and transcriptional activities in response to stress.Dial 9-1-1 for p53: mechanisms of p53 activation by cellular stressAcetylation of p53 at lysine 373/382 by the histone deacetylase inhibitor depsipeptide induces expression of p21(Waf1/Cip1).Epstein-Barr virus nuclear antigen 3C targets p53 and modulates its transcriptional and apoptotic activities.DNA damage induces phosphorylation of the amino terminus of p53Identification of a novel class of genomic DNA-binding sites suggests a mechanism for selectivity in target gene activation by the tumor suppressor protein p53Mdm2 is required for inhibition of Cdk2 activity by p21, thereby contributing to p53-dependent cell cycle arrestFunctional activation of p53 via phosphorylation following DNA damage by UV but not gamma radiation.Phosphorylation at carboxyl-terminal S373 and S375 residues and 14-3-3 binding are not required for mouse p53 functionHSP70 binding sites in the tumor suppressor protein p53.Identification of an additional negative regulatory region for p53 sequence-specific DNA bindingGlycerol restores p53-dependent radiosensitivity of human head and neck cancer cells bearing mutant p53.The single-stranded DNA end binding site of p53 coincides with the C-terminal regulatory region.Constitutive DNase I hypersensitivity of p53-regulated promoters.The p53 tumour suppressor gene.The expanding role of the Ehmt2/G9a complex in neurodevelopment.
P2860
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P2860
Regulation of the sequence-specific DNA binding function of p53 by protein kinase C and protein phosphatases.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Regulation of the sequence-spe ...... se C and protein phosphatases.
@en
type
label
Regulation of the sequence-spe ...... se C and protein phosphatases.
@en
prefLabel
Regulation of the sequence-spe ...... se C and protein phosphatases.
@en
P2093
P2860
P356
P1476
Regulation of the sequence-spe ...... se C and protein phosphatases.
@en
P2093
P2860
P304
P356
10.1074/JBC.270.10.5405
P407
P577
1995-03-01T00:00:00Z