DNA-binding and strand-annealing activities of human Mre11: implications for its roles in DNA double-strand break repair pathways.
about
Unwinding and rewinding: double faces of helicase?RAD50 and NBS1 form a stable complex functional in DNA binding and tetheringHuman RECQ5beta, a protein with DNA helicase and strand-annealing activities in a single polypeptideSaccharomyces cerevisiae Mre11 is a high-affinity G4 DNA-binding protein and a G-rich DNA-specific endonuclease: implications for replication of telomeric DNADNA Damage Signalling and Repair Inhibitors: The Long-Sought-After Achilles' Heel of CancerThe Role of the COP9 Signalosome and Neddylation in DNA Damage Signaling and RepairUbiquitylation, neddylation and the DNA damage responseRAD50, an SMC family member with multiple roles in DNA break repair: how does ATP affect function?Mechanisms for Structural Variation in the Human GenomeRad51 protein controls Rad52-mediated DNA annealing.Biochemistry of Meiotic Recombination: Formation, Processing, and Resolution of Recombination Intermediates.Blunt-ended DNA double-strand breaks induced by endonucleases PvuII and EcoRV are poor substrates for repair in Saccharomyces cerevisiae.The MRE11 GAR motif regulates DNA double-strand break processing and ATR activation.The MRN complex in double-strand break repair and telomere maintenance.hMRE11 deficiency leads to microsatellite instability and defective DNA mismatch repair.A new type of radiosensitive T-B-NK+ severe combined immunodeficiency caused by a LIG4 mutation.Characterization of RAD51-independent break-induced replication that acts preferentially with short homologous sequencesSV40 large T-antigen disturbs the formation of nuclear DNA-repair foci containing MRE11.Mechanism and regulation of class switch recombinationDNA double-strand break repair by homologous recombination.Insight into the mechanism of inhibition of adeno-associated virus by the Mre11/Rad50/Nbs1 complexMild hyperthermia inhibits homologous recombination, induces BRCA2 degradation, and sensitizes cancer cells to poly (ADP-ribose) polymerase-1 inhibition.Identification of Mre11 as a target for heat radiosensitization.Mre11-Rad50 complex crystals suggest molecular calisthenics.The role of DNA exonucleases in protecting genome stability and their impact on ageing.Cisplatin sensitizes cancer cells to ionizing radiation via inhibition of nonhomologous end joining.Processing of DNA double-stranded breaks and intermediates of recombination and repair by Saccharomyces cerevisiae Mre11 and its stimulation by Rad50, Xrs2, and Sae2 proteins.Mre11-Rad50-Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin template.Kinase-dead ATM protein is highly oncogenic and can be preferentially targeted by Topo-isomerase I inhibitorsProcessive and unidirectional translocation of monomeric UvsW helicase on single-stranded DNA.Coordination and processing of DNA ends during double-strand break repair: the role of the bacteriophage T4 Mre11/Rad50 (MR) complex.Cohesin association to replication sites depends on rad50 and promotes fork restartEffects of tumor-suppressor lysyl oxidase propeptide on prostate cancer xenograft growth and its direct interactions with DNA repair pathways.Mre11 modulates the fidelity of fusion between short telomeres in human cells.DNA end-binding specificity of human Rad50/Mre11 is influenced by ATP.Rad52 and Ku bind to different DNA structures produced early in double-strand break repairYeast Mre11 and Rad1 proteins define a Ku-independent mechanism to repair double-strand breaks lacking overlapping end sequences.Nbs1 is essential for DNA repair by homologous recombination in higher vertebrate cells.Cell cycle-dependent role of MRN at dysfunctional telomeres: ATM signaling-dependent induction of nonhomologous end joining (NHEJ) in G1 and resection-mediated inhibition of NHEJ in G2Post-translational methylations of the archaeal Mre11:Rad50 complex throughout the DNA damage response.
P2860
Q21296726-467DF17D-0221-46AF-A3C6-67F99128AD59Q24317537-CEAA0A8F-0BB6-4B52-B030-A45CE0AB47FEQ24563101-42C476DD-66F6-4FD2-AD9E-79D956B08033Q24814949-86B7CD6A-DAAF-4429-91F2-61DF24864416Q26776513-4E9784B8-74DD-4F85-8AF7-525D6AB381CAQ26782011-3915BF97-08B3-496A-8A33-0CC2B56A70A5Q28087342-E5BEF71C-A835-44AE-9B6C-EEA1799AE8D1Q28239071-743511E2-4AF0-4D35-8113-678AB61D4396Q30412742-93CC7DC3-906F-463A-844E-679E532CFC19Q33323517-B1FFE275-00BB-415F-BDAF-7E5EACD8D8A3Q33604620-C0A5B0B9-FF3E-4967-A3F7-ECB9C40BF8D2Q33905610-0B3929CE-10A1-44D2-B19C-D225759CEC2DQ33985893-FE11D1B0-AF0C-4E5E-91AA-2887C8236507Q34127693-70EB5804-AD35-440C-92AA-B13FCCDBA3DBQ34166799-0AE4512A-D59C-4E19-9087-13AB899B79DFQ34211015-66435965-9D8F-4D9A-A36D-C815F5634F20Q34325056-ED2A481C-BA0C-4A72-B6DD-DEFA6EAF4FF3Q34739797-BDB01097-5853-487D-BAAA-A3B7E55214B4Q34764888-F1D21B07-6F25-427B-AC44-AEC614D86F54Q34835417-FAE38301-91FB-4649-A5B7-8077B8E99186Q34992549-01317B4D-C1AB-498D-B663-DFC48ACE702EQ35049271-2D4C6914-7AA9-4D23-B2DC-7CD31A8F6577Q35217488-C5324845-121C-4FC1-A4DC-0CA51F58CBABQ35256261-F3DFAD9B-ACE4-44E3-95A7-6304EBF9721FQ36483126-C88678FD-F2E1-4697-B4E0-594261362E11Q36728874-73A1B904-7833-44E3-BE59-DDB549876B0CQ36779483-5569073A-0EF5-4125-AE93-200EA891CA5AQ36916670-9A613099-D914-4FC2-AD47-ADD7F5A92991Q37119667-E85D8BD9-9EF5-4EB9-8AD6-44F49812AE1BQ37134113-735CA604-BD30-4688-B886-8380BD4FD3D6Q37269795-A2284DF9-EA69-47EF-A5BE-CC40F5C97430Q37524723-3CC8A0DD-5CBC-4D07-B3A9-72AC0DEBB53FQ38989588-85DC569B-7EA9-4D50-90F6-66715B6C1B47Q39433229-A14392FF-5BEA-4E15-9C07-AF7E30E73779Q39687245-1B438E5E-98D2-4CCD-9F14-C9B634EF21D8Q39922609-01644D45-D509-4B60-A55B-D5F8AB52EC4BQ40173836-6A599811-3B7B-4F3C-AD45-9280BC71789EQ40691380-69AA148D-1FBA-4875-B0D3-E3B6C4EAE24CQ42117260-755CBF3F-092B-43D5-A115-7692E74306EBQ42486978-4AD4441E-EE08-45D1-8C24-0F91D973FBD9
P2860
DNA-binding and strand-annealing activities of human Mre11: implications for its roles in DNA double-strand break repair pathways.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
DNA-binding and strand-anneali ...... -strand break repair pathways.
@en
type
label
DNA-binding and strand-anneali ...... -strand break repair pathways.
@en
prefLabel
DNA-binding and strand-anneali ...... -strand break repair pathways.
@en
P2093
P2860
P356
P1476
DNA-binding and strand-anneali ...... -strand break repair pathways.
@en
P2093
C E Beerens
D C van Gent
M L Dronkert
M de Jager
P2860
P304
P356
10.1093/NAR/29.6.1317
P407
P577
2001-03-01T00:00:00Z