Alzheimer amyloid protein precursor complexes with brain GTP-binding protein G(o)
about
APP-BP1 mediates APP-induced apoptosis and DNA synthesis and is increased in Alzheimer's disease brainFKBP12 regulates the localization and processing of amyloid precursor protein in human cell linesFe65L2: a new member of the Fe65 protein family interacting with the intracellular domain of the Alzheimer's beta-amyloid precursor proteinTransforming growth factor beta2 is a neuronal death-inducing ligand for amyloid-beta precursor proteinThe amyloid-beta precursor protein: integrating structure with biological functionDysfunction of amyloid precursor protein signaling in neurons leads to DNA synthesis and apoptosisInsights into the physiological function of the β-amyloid precursor protein: beyond Alzheimer's diseaseAmyloid β precursor protein as a molecular target for amyloid β--induced neuronal degeneration in Alzheimer's diseaseDiminished CRE-Induced Plasticity is Linked to Memory Deficits in Familial Alzheimer's Disease MiceStructure of Alzheimer's disease amyloid precursor protein copper-binding domain at atomic resolutionStructure of the C-terminal phosphotyrosine interaction domain of Fe65L1 complexed with the cytoplasmic tail of amyloid precursor protein reveals a novel peptide binding modeStructure of amyloid A4-(1-40)-peptide of Alzheimer's diseaseDirect control of exocytosis by receptor-mediated activation of the heterotrimeric GTPases Gi and G(o) or by the expression of their active G alpha subunits.Role of Drosophila Amyloid Precursor Protein in Memory FormationThe beta-amyloid precursor protein functions as a cytosolic anchoring site that prevents Fe65 nuclear translocationCaveolae, plasma membrane microdomains for alpha-secretase-mediated processing of the amyloid precursor proteinFe65 and the protein network centered around the cytosolic domain of the Alzheimer's beta-amyloid precursor proteinCD9 of mouse brain is implicated in neurite outgrowth and cell migration in vitro and is associated with the alpha 6/beta 1 integrin and the neural adhesion molecule L1The intracellular cytoplasmic domain of the Alzheimer's disease amyloid precursor protein interacts with phosphotyrosine-binding domain proteins in the yeast two-hybrid systemInteraction of the phosphotyrosine interaction/phosphotyrosine binding-related domains of Fe65 with wild-type and mutant Alzheimer's beta-amyloid precursor proteinsIntracellular trafficking and synaptic function of APL-1 in Caenorhabditis elegansThe in vivo brain interactome of the amyloid precursor proteinMultiple neurological abnormalities in mice deficient in the G protein GoP60TRP interferes with the GPCR/secretase pathway to mediate neuronal survival and synaptogenesisAmyloid Precursor Proteins Are Dynamically Trafficked and Processed during Neuronal Development.Characterization of the major bovine brain Go alpha isoforms. Mapping the structural differences between the alpha subunit isoforms identifies a variable region of the protein involved in receptor interactions.Molecular mechanisms of go signalingThe insect homologue of the amyloid precursor protein interacts with the heterotrimeric G protein Go alpha in an identified population of migratory neurons.The beta-amyloid precursor protein and its derivatives: from biology to learning and memory processes.Abnormalities in G protein-coupled signal transduction pathways in human disease.Implications of non-canonical G-protein signaling for the immune systemFirst evidence of overlaps between HIV-Associated Dementia (HAD) and non-viral neurodegenerative diseases: proteomic analysis of the frontal cortex from HIV+ patients with and without dementia.The functions of the amyloid precursor protein gene.Alzheimer and beta-amyloid-treated fibroblasts demonstrate a decrease in a memory-associated GTP-binding protein, Cp20Death and survival of neuronal cells exposed to Alzheimer's insults.Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease.Amyloid precursor protein enhances Nav1.6 sodium channel cell surface expressionHolo-APP and G-protein-mediated signaling are required for sAPPα-induced activation of the Akt survival pathway.Intrinsic signaling function of APP as a novel target of three V642 mutations linked to familial Alzheimer's disease.Analysis by a highly sensitive split luciferase assay of the regions involved in APP dimerization and its impact on processing.
P2860
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P2860
Alzheimer amyloid protein precursor complexes with brain GTP-binding protein G(o)
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh
1993年學術文章
@zh-hant
name
Alzheimer amyloid protein precursor complexes with brain GTP-binding protein G(o)
@en
type
label
Alzheimer amyloid protein precursor complexes with brain GTP-binding protein G(o)
@en
prefLabel
Alzheimer amyloid protein precursor complexes with brain GTP-binding protein G(o)
@en
P2093
P356
P1433
P1476
Alzheimer amyloid protein precursor complexes with brain GTP-binding protein G(o)
@en
P2093
P2888
P356
10.1038/362075A0
P407
P577
1993-03-01T00:00:00Z
P6179
1040577875