Minimal methylated substrate and extended substrate range of Escherichia coli AlkB protein, a 1-methyladenine-DNA dioxygenase.
about
Human ABH3 structure and key residues for oxidative demethylation to reverse DNA/RNA damageMutagenesis, genotoxicity, and repair of 1-methyladenine, 3-alkylcytosines, 1-methylguanine, and 3-methylthymine in alkB Escherichia coliA non-heme iron-mediated chemical demethylation in DNA and RNAAlleviation of 1,N6-ethanoadenine genotoxicity by the Escherichia coli adaptive response protein AlkBEnzymological and structural studies of the mechanism of promiscuous substrate recognition by the oxidative DNA repair enzyme AlkBStructural and Mutational Analysis of Escherichia coli AlkB Provides Insight into Substrate Specificity and DNA Damage SearchingAlkB reverses etheno DNA lesions caused by lipid oxidation in vitro and in vivoCrystal structures of catalytic complexes of the oxidative DNA/RNA repair enzyme AlkBHuman ALKBH4 interacts with proteins associated with transcriptionRepair of methylation damage in DNA and RNA by mammalian AlkB homologuesImpaired placental trophoblast lineage differentiation in Alkbh1(-/-) miceDistinct mechanisms of cis-syn thymine dimer bypass by Dpo4 and DNA polymerase etaProtein dynamics control the progression and efficiency of the catalytic reaction cycle of the Escherichia coli DNA-repair enzyme AlkBProtozoan ALKBH8 oxygenases display both DNA repair and tRNA modification activities.Expression and sub-cellular localization of human ABH family molecules.Differential repair of etheno-DNA adducts by bacterial and human AlkB proteinsGenome sequence and analysis of the soil cellulolytic actinomycete Thermobifida fusca YXThe DNA dioxygenase ALKBH2 protects Arabidopsis thaliana against methylation damage.Kinetic studies of Escherichia coli AlkB using a new fluorescence-based assay for DNA demethylation.Direct reversal of DNA alkylation damage.Oxidative dealkylation DNA repair mediated by the mononuclear non-heme iron AlkB proteinsAlkB dioxygenase preferentially repairs protonated substrates: specificity against exocyclic adducts and molecular mechanism of action.The Genomes of Three Uneven Siblings: Footprints of the Lifestyles of Three Trichoderma Species.Direct repair of the exocyclic DNA adduct 1,N6-ethenoadenine by the DNA repair AlkB proteins.Fluorescence Monitoring of the Oxidative Repair of DNA Alkylation Damage by ALKBH3, a Prostate Cancer Marker.Bioinformatics and functional analysis define four distinct groups of AlkB DNA-dioxygenases in bacteria.Nucleic acid oxidation in DNA damage repair and epigeneticsDamage of DNA and proteins by major lipid peroxidation products in genome stability.My journey to DNA repair.CGmCGCG is a versatile substrate with which to evaluate Tet protein activity.Mechanistic studies on the application of DNA aptamers as inhibitors of 2-oxoglutarate-dependent oxygenases.Substrate specificities of bacterial and human AlkB proteins.Non-homologous functions of the AlkB homologs.Repair of 3-methylthymine and 1-methylguanine lesions by bacterial and human AlkB proteins.Computational investigation of O2 diffusion through an intra-molecular tunnel in AlkB; influence of polarization on O2 transport.Fe(II)/alpha-ketoglutarate hydroxylases involved in nucleobase, nucleoside, nucleotide, and chromatin metabolism.Demethylation of 3-methylthymine in DNA by bacterial and human DNA dioxygenases.Biochemical Characterization of AP Lyase and m6A Demethylase Activities of Human AlkB Homologue 1 (ALKBH1).Base-excision repair and beyond --A short summary attributed to scientific achievements of Tomas Lindahl, Nobel Prize Laureate in Chemistry 2015.
P2860
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P2860
Minimal methylated substrate and extended substrate range of Escherichia coli AlkB protein, a 1-methyladenine-DNA dioxygenase.
description
2003 nî lūn-bûn
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2003年の論文
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2003年学术文章
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2003年学术文章
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name
Minimal methylated substrate a ...... methyladenine-DNA dioxygenase.
@en
type
label
Minimal methylated substrate a ...... methyladenine-DNA dioxygenase.
@en
prefLabel
Minimal methylated substrate a ...... methyladenine-DNA dioxygenase.
@en
P2093
P2860
P356
P1476
Minimal methylated substrate a ...... methyladenine-DNA dioxygenase.
@en
P2093
Barbara Sedgwick
Pertti Koivisto
Tod Duncan
P2860
P304
44348-44354
P356
10.1074/JBC.M307361200
P407
P577
2003-08-27T00:00:00Z