Reconciliation of the X-ray and NMR structures of the thrombin-binding aptamer d(GGTTGGTGTGGTTGG).
about
Quadruplex DNA: sequence, topology and structureDirect evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcriptionInteractions of the G quartet forming semaphorin 3F RNA with the RGG box domain of the fragile X protein familyThe effect of chemical modifications on the thermal stability of different G-quadruplex-forming oligonucleotidesNot so crystal clear: the structure of the human telomere G-quadruplex in solution differs from that present in a crystalThrombin-aptamer recognition: a revealed ambiguityStacking of G-quadruplexes: NMR structure of a G-rich oligonucleotide with potential anti-HIV and anticancer activityHigh-resolution structures of two complexes between thrombin and thrombin-binding aptamer shed light on the role of cations in the aptamer inhibitory activityCarbohydrate-DNA interactions at G-quadruplexes: folding and stability changes by attaching sugars at the 5'-endAn update on recent patents on thrombin inhibitors (2010 - 2013)Thrombin-Binding Aptamer Quadruplex Formation: AFM and Voltammetric Characterization.Topology of a G-quadruplex DNA formed by C9orf72 hexanucleotide repeats associated with ALS and FTD.Insulin capture by an insulin-linked polymorphic region G-quadruplex DNA oligonucleotide.Acyclic identification of aptamers for human alpha-thrombin using over-represented libraries and deep sequencing.Structure of the biologically relevant G-quadruplex in the c-MYC promoter.Quadruplex structures in nucleic acids.Biological aspects of DNA/RNA quadruplexes.Improved thrombin binding aptamer by incorporation of a single unlocked nucleic acid monomer.Biophysical and biological properties of quadruplex oligodeoxyribonucleotidesKinetics and mechanism of G-quadruplex formation and conformational switch in a G-quadruplex of PS2.M induced by Pb²⁺Site specific replacements of a single loop nucleoside with a dibenzyl linker may switch the activity of TBA from anticoagulant to antiproliferative.Characterization of the G-quadruplexes in the duplex nuclease hypersensitive element of the PDGF-A promoter and modulation of PDGF-A promoter activity by TMPyP4Human telomere, oncogenic promoter and 5'-UTR G-quadruplexes: diverse higher order DNA and RNA targets for cancer therapeutics.G-ruption: the third international meeting on G-quadruplex and G-assembly.Effect of locked-nucleic acid on a biologically active g-quadruplex. A structure-activity relationship of the thrombin aptamerA novel chair-type G-quadruplex formed by a Bombyx mori telomeric sequenceApplications of isothermal titration calorimetry in biophysical studies of G-quadruplexes.Conformationally rigid nucleoside probes help understand the role of sugar pucker and nucleobase orientation in the thrombin-binding aptamerOverview of formation of G-quadruplex structures.Characterization of aptamer-protein complexes by X-ray crystallography and alternative approaches.Functional DNA switches: rational design and electrochemical signaling.Structural Characterization of a Thrombin-Aptamer Complex by High Resolution Native Top-Down Mass Spectrometry.Site-specific replacement of the thymine methyl group by fluorine in thrombin binding aptamer significantly improves structural stability and anticoagulant activity.Stability and binding properties of a modified thrombin binding aptamer.G-quadruplex induced stabilization by 2'-deoxy-2'-fluoro-D-arabinonucleic acids (2'F-ANA).Anomeric DNA quadruplexes.Stability and bioactivity of thrombin binding aptamers modified with D-/L-isothymidine in the loop regions.Structure variations of TBA G-quadruplex induced by 2'-O-methyl nucleotide in K+ and Ca2+ environments.5-Hydroxymethyl-2'-deoxyuridine residues in the thrombin binding aptamer: investigating anticoagulant activity by making a tiny chemical modification.Unfolding and conformational variations of thrombin-binding DNA aptamers: synthesis, circular dichroism and molecular dynamics simulations.
P2860
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P2860
Reconciliation of the X-ray and NMR structures of the thrombin-binding aptamer d(GGTTGGTGTGGTTGG).
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Reconciliation of the X-ray an ...... ng aptamer d(GGTTGGTGTGGTTGG).
@en
type
label
Reconciliation of the X-ray an ...... ng aptamer d(GGTTGGTGTGGTTGG).
@en
prefLabel
Reconciliation of the X-ray an ...... ng aptamer d(GGTTGGTGTGGTTGG).
@en
P356
P1476
Reconciliation of the X-ray an ...... ng aptamer d(GGTTGGTGTGGTTGG).
@en
P2093
P304
P356
10.1006/JMBI.1996.0097
P407
P577
1996-03-01T00:00:00Z