Coordinated regulation of Rap1 and thyroid differentiation by cyclic AMP and protein kinase A.
about
The guanine nucleotide exchange factor CNrasGEF regulates melanogenesis and cell survival in melanoma cellsRap1a is a key regulator of fibroblast growth factor 2-induced angiogenesis and together with Rap1b controls human endothelial cell functionsRole of Rap1B and tumor suppressor PTEN in the negative regulation of lysophosphatidic acid--induced migration by isoproterenol in glioma cellsDelocalization of Endogenous A-kinase Antagonizes Rap1-Rho-α2C-Adrenoceptor Signaling in Human Microvascular Smooth Muscle CellsActivation of Gz attenuates Rap1-mediated differentiation of PC12 cellsRap1 promotes multiple pancreatic islet cell functions and signals through mammalian target of rapamycin complex 1 to enhance proliferationProtein kinase A and B-Raf mediate extracellular signal-regulated kinase activation by thyrotropinDownregulation of Rap1GAP contributes to Ras transformationCyclic AMP signaling inhibits megakaryocytic differentiation by targeting transcription factor 3 (E2A) cyclin-dependent kinase inhibitor 1A (CDKN1A) transcriptional axis.cAMP-dependent activation of mammalian target of rapamycin (mTOR) in thyroid cells. Implication in mitogenesis and activation of CDK4.A Rap/phosphatidylinositol 3-kinase pathway controls pseudopod formation [corrected].Follicular thyroid cancers demonstrate dual activation of PKA and mTOR as modeled by thyroid-specific deletion of Prkar1a and Pten in mice.Generation of cyclic ADP-ribose and nicotinic acid adenine dinucleotide phosphate by CD38 for Ca2+ signaling in interleukin-8-treated lymphokine-activated killer cells.On the mitogenic properties of Rap1b: cAMP-induced G(1)/S entry requires activated and phosphorylated Rap1b.PI3K/AKT pathway mediates induction of IL-1RA by TSH in fibrocytes: modulation by PTENSwitch in signaling control of mTORC1 activity after oncoprotein expression in thyroid cancer cell lines.Rap1GAP impairs cell-matrix adhesion in the absence of effects on cell-cell adhesionRap1 promotes cell spreading by localizing Rac guanine nucleotide exchange factorsA critical role of Rap1b in B-cell trafficking and marginal zone B-cell development.Regulation of inhibitors of differentiation family proteins by thyroid-stimulating hormone in FRTL-5 thyroid cells.Modulation of sodium iodide symporter expression and function by LY294002, Akti-1/2 and Rapamycin in thyroid cellsSmall G proteins as key regulators of pancreatic digestive enzyme secretion.Hindbrain GLP-1 receptor-mediated suppression of food intake requires a PI3K-dependent decrease in phosphorylation of membrane-bound Akt.Gastrointestinal growth factors and hormones have divergent effects on Akt activation.Effect of Thyrotropin on Osteopontin, Integrin αvβ3, and VCAM-1 in the Endothelium via Activation of Akt.Intracellular signal transduction as a factor in the development of "smart" biomaterials for bone tissue engineering.Cyclic AMP-induced forkhead transcription factor, FKHR, cooperates with CCAAT/enhancer-binding protein beta in differentiating human endometrial stromal cells.Thyrotropin regulates IL-6 expression in CD34+ fibrocytes: clear delineation of its cAMP-independent actions.Rap1 mutants with increased affinity for the guanine-nucleotide exchange factor C3G.Effects of sodium ions on rat thyrocyte (FRTL-5 cells) swelling- and thyrotropin-activated taurine efflux dependent on cAMP and Epac.Cyclic AMP-mediated inhibition of cell growth requires the small G protein Rap1.Histone deacetylase inhibitors upregulate Rap1GAP and inhibit Rap activity in thyroid tumor cells.A novel Epac-Rap-PP2A signaling module controls cAMP-dependent Akt regulationEpac, in synergy with cAMP-dependent protein kinase (PKA), is required for cAMP-mediated mitogenesis.Activation of Rac by cadherin through the c-Src-Rap1-phosphatidylinositol 3-kinase-Vav2 pathway.The cAMP-Epac-Rap1 pathway regulates cell spreading and cell adhesion to laminin-5 through the alpha3beta1 integrin but not the alpha6beta4 integrin.Thyroid-stimulating hormone/cAMP and glycogen synthase kinase 3beta elicit opposing effects on Rap1GAP stability.Differential involvement of the Ras and Rap1 small GTPases in vasoactive intestinal and pituitary adenylyl cyclase activating polypeptides control of the prolactin gene.Enhanced sensitivity to apoptosis in Ras-transformed thyroid cells.Rap1 activation plays a regulatory role in pancreatic amylase secretion.
P2860
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P2860
Coordinated regulation of Rap1 and thyroid differentiation by cyclic AMP and protein kinase A.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Coordinated regulation of Rap1 ...... clic AMP and protein kinase A.
@en
Coordinated regulation of Rap1 ...... clic AMP and protein kinase A.
@nl
type
label
Coordinated regulation of Rap1 ...... clic AMP and protein kinase A.
@en
Coordinated regulation of Rap1 ...... clic AMP and protein kinase A.
@nl
prefLabel
Coordinated regulation of Rap1 ...... clic AMP and protein kinase A.
@en
Coordinated regulation of Rap1 ...... clic AMP and protein kinase A.
@nl
P2093
P2860
P1476
Coordinated regulation of Rap1 ...... clic AMP and protein kinase A.
@en
P2093
A Saavedra
J F Rebhun
J L Meinkoth
L A Quilliam
O M Tsygankova
P2860
P304
P356
10.1128/MCB.21.6.1921-1929.2001
P407
P577
2001-03-01T00:00:00Z