cAMP-dependent activation of mammalian target of rapamycin (mTOR) in thyroid cells. Implication in mitogenesis and activation of CDK4.
about
CDK4 T172 phosphorylation is central in a CDK7-dependent bidirectional CDK4/CDK2 interplay mediated by p21 phosphorylation at the restriction pointCatecholamine-induced lipolysis causes mTOR complex dissociation and inhibits glucose uptake in adipocytes.Follicular thyroid cancers demonstrate dual activation of PKA and mTOR as modeled by thyroid-specific deletion of Prkar1a and Pten in mice.Wnt-independent role of β-catenin in thyroid cell proliferation and differentiation.FOXO1 controls thyroid cell proliferation in response to TSH and IGF-I and is involved in thyroid tumorigenesis.Activation of D1R/PKA/mTOR signaling cascade in medial prefrontal cortex underlying the antidepressant effects of l-SPD.Switch in signaling control of mTORC1 activity after oncoprotein expression in thyroid cancer cell lines.mTOR pathway is activated by PKA in adrenocortical cells and participates in vivo to apoptosis resistance in primary pigmented nodular adrenocortical disease (PPNAD).Hypoxia-inducible factor-1α restricts the anabolic actions of parathyroid hormone.The CDK4/CDK6 inhibitor PD0332991 paradoxically stabilizes activated cyclin D3-CDK4/6 complexes.Prostaglandin E2 activates the mTORC1 pathway through an EP4/cAMP/PKA- and EP1/Ca2+-mediated mechanism in the human pancreatic carcinoma cell line PANC-1Rapamycin Blocks Induction of the Thermogenic Program in White Adipose Tissue.Activation of mTORC1 is essential for β-adrenergic stimulation of adipose browning.The regulation of autophagy - unanswered questions.The mTOR protein as a target in thyroid cancer.Role of PRAS40 in Akt and mTOR signaling in health and disease.An overview of autophagy: morphology, mechanism, and regulation.mTOR in Brain Physiology and Pathologies.cAMP inhibits mammalian target of rapamycin complex-1 and -2 (mTORC1 and 2) by promoting complex dissociation and inhibiting mTOR kinase activity.A novel role for AMP-kinase in the regulation of the Na+/I--symporter and iodide uptake in the rat thyroid gland.JNKs function as CDK4-activating kinases by phosphorylating CDK4 and p21.CDK4 phosphorylation status and a linked gene expression profile predict sensitivity to palbociclib.Effect of beta-agonists on LAM progression and treatment.E2F1 promotes hepatic gluconeogenesis and contributes to hyperglycemia during diabetes.Thyroid nodules on chest CT of patients with tuberous sclerosis complex.
P2860
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P2860
cAMP-dependent activation of mammalian target of rapamycin (mTOR) in thyroid cells. Implication in mitogenesis and activation of CDK4.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
cAMP-dependent activation of m ...... enesis and activation of CDK4.
@ast
cAMP-dependent activation of m ...... enesis and activation of CDK4.
@en
type
label
cAMP-dependent activation of m ...... enesis and activation of CDK4.
@ast
cAMP-dependent activation of m ...... enesis and activation of CDK4.
@en
prefLabel
cAMP-dependent activation of m ...... enesis and activation of CDK4.
@ast
cAMP-dependent activation of m ...... enesis and activation of CDK4.
@en
P2093
P2860
P356
P1476
cAMP-dependent activation of m ...... enesis and activation of CDK4.
@en
P2093
Jacques E Dumont
Katia Coulonval
Pierre P Roger
Sabine Paternot
Sara Blancquaert
Thurl E Harris
P2860
P304
P356
10.1210/ME.2010-0087
P577
2010-05-19T00:00:00Z