A broader role for AU-rich element-mediated mRNA turnover revealed by a new transcriptional pulse strategy.
about
Coordinate regulation of GATA-3 and Th2 cytokine gene expression by the RNA-binding protein HuRIdentification of TINO: a new evolutionarily conserved BCL-2 AU-rich element RNA-binding proteinThe BTG2 protein is a general activator of mRNA deadenylationMK2-induced tristetraprolin:14-3-3 complexes prevent stress granule association and ARE-mRNA decayFunctional cloning of BRF1, a regulator of ARE-dependent mRNA turnover.AU-rich elements and associated factors: are there unifying principles?Highly selective actions of HuR in antagonizing AU-rich element-mediated mRNA destabilizationThe ARE-dependent mRNA-destabilizing activity of BRF1 is regulated by protein kinase BHuman TOB, an antiproliferative transcription factor, is a poly(A)-binding protein-dependent positive regulator of cytoplasmic mRNA deadenylationUse of mRNA- and protein-destabilizing elements to develop a highly responsive reporter systemMechanisms of deadenylation-dependent decayGlobal analysis of Pub1p targets reveals a coordinate control of gene expression through modulation of binding and stabilityBRF1 protein turnover and mRNA decay activity are regulated by protein kinase B at the same phosphorylation sites3'-Untranslated region of phosphoenolpyruvate carboxykinase mRNA contains multiple instability elements that bind AUF1Concerted action of poly(A) nucleases and decapping enzyme in mammalian mRNA turnoverMessenger RNA turnover in eukaryotes: pathways and enzymesRegulation of heme oxygenase-1 mRNA deadenylation and turnover in NIH3T3 cells by nitrosative or alkylation stressDeadenylation is prerequisite for P-body formation and mRNA decay in mammalian cellsSelective degradation of AU-rich mRNAs promoted by the p37 AUF1 protein isoformRapid deadenylation triggered by a nonsense codon precedes decay of the RNA body in a mammalian cytoplasmic nonsense-mediated decay pathwayRNA stabilization by the AU-rich element binding protein, HuR, an ELAV proteinTracing the molecular basis of transcriptional dynamics in noisy data by using an experiment-based mathematical model.The p38 MAPK regulates IL-24 expression by stabilization of the 3' UTR of IL-24 mRNA.Versatile role for hnRNP D isoforms in the differential regulation of cytoplasmic mRNA turnover.Down-regulation of cyclin D1 expression by prostaglandin A(2) is mediated by enhanced cyclin D1 mRNA turnover.The 3' untranslated region of tumor necrosis factor alpha mRNA is a target of the mRNA-stabilizing factor HuR.Ubiquitin-dependent mechanism regulates rapid turnover of AU-rich cytokine mRNAs.Ago-TNRC6 triggers microRNA-mediated decay by promoting two deadenylation steps.Increased stability of the p16 mRNA with replicative senescenceThe protein Zfand5 binds and stabilizes mRNAs with AU-rich elements in their 3'-untranslated regions.A reverse time-course method for transcriptional chase analyses of mRNA half-lives in cultured cells.Mature mRNAs accumulated in the nucleus are neither the molecules in transit to the cytoplasm nor constitute a stockpile for gene expression.Cellular mutants define a common mRNA degradation pathway targeting cytokine AU-rich elements.Functional dissection of hnRNP D suggests that nuclear import is required before hnRNP D can modulate mRNA turnover in the cytoplasmPhosphorylation of tristetraprolin by MK2 impairs AU-rich element mRNA decay by preventing deadenylase recruitment.Allelic variation in PtGA20Ox associates with growth and wood properties in Populus sppA constitutive decay element promotes tumor necrosis factor alpha mRNA degradation via an AU-rich element-independent pathway.Unraveling a cytoplasmic role for hnRNP D in the in vivo mRNA destabilization directed by the AU-rich element.AUF-1 and YB-1 independently regulate β-globin mRNA in developing erythroid cells through interactions with poly(A)-binding proteinAUF-1 and YB-1 are critical determinants of β-globin mRNA expression in erythroid cells.
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P2860
A broader role for AU-rich element-mediated mRNA turnover revealed by a new transcriptional pulse strategy.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
A broader role for AU-rich ele ...... ranscriptional pulse strategy.
@en
A broader role for AU-rich ele ...... ranscriptional pulse strategy.
@nl
type
label
A broader role for AU-rich ele ...... ranscriptional pulse strategy.
@en
A broader role for AU-rich ele ...... ranscriptional pulse strategy.
@nl
prefLabel
A broader role for AU-rich ele ...... ranscriptional pulse strategy.
@en
A broader role for AU-rich ele ...... ranscriptional pulse strategy.
@nl
P2093
P2860
P356
P1476
A broader role for AU-rich ele ...... ranscriptional pulse strategy.
@en
P2093
P2860
P304
P356
10.1093/NAR/26.2.558
P407
P577
1998-01-01T00:00:00Z