Intrinsic differences in the response of the human lutropin receptor versus the human follitropin receptor to activating mutations.
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Signaling through FSH receptors on human umbilical vein endothelial cells promotes angiogenesis.Female mice expressing constitutively active mutants of FSH receptor present with a phenotype of premature follicle depletion and estrogen excessThe luteinizing hormone receptor: insights into structure-function relationships and hormone-receptor-mediated changes in gene expression in ovarian cancer cells.Revisiting and questioning functional rescue between dimerized LH receptor mutants.Misfolding Ectodomain Mutations of the Lutropin Receptor Increase Efficacy of Hormone StimulationAn intracellular loop (IL2) residue confers different basal constitutive activities to the human lutropin receptor and human thyrotropin receptor through structural communication between IL2 and helix 6, via helix 3.Bioluminescence resonance energy transfer studies reveal constitutive dimerization of the human lutropin receptor and a lack of correlation between receptor activation and the propensity for dimerization.Constitutive activation of G protein-coupled receptors and diseases: insights into mechanisms of activation and therapeutics.Heterodimerization between the lutropin and follitropin receptors is associated with an attenuation of hormone-dependent signaling.A cell surface inactive mutant of the human lutropin receptor (hLHR) attenuates signaling of wild-type or constitutively active receptors via heterodimerization.Structural determinants underlying constitutive dimerization of unoccupied human follitropin receptors.The Follitropin Receptor: Matching Structure and Function.Differential Regulation of Human and Mouse Myometrial Contractile Activity by FSH as a Function of FSH Receptor Density.Structure and activation of the TSH receptor transmembrane domain.Ablation of LGR4 promotes energy expenditure by driving white-to-brown fat switch.Modeling GPCR active state conformations: the β(2)-adrenergic receptor.
P2860
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P2860
Intrinsic differences in the response of the human lutropin receptor versus the human follitropin receptor to activating mutations.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Intrinsic differences in the r ...... eptor to activating mutations.
@en
type
label
Intrinsic differences in the r ...... eptor to activating mutations.
@en
prefLabel
Intrinsic differences in the r ...... eptor to activating mutations.
@en
P2093
P2860
P356
P1476
Intrinsic differences in the r ...... ceptor to activating mutations
@en
P2093
Deborah L Segaloff
Ginny L Ryan
Meilin Zhang
Xiuyan Feng
P2860
P304
25527-25539
P356
10.1074/JBC.M703500200
P407
P577
2007-07-02T00:00:00Z