Iron chelation and regulation of the cell cycle: 2 mechanisms of posttranscriptional regulation of the universal cyclin-dependent kinase inhibitor p21CIP1/WAF1 by iron depletion.
about
RNA-Binding Proteins in Trichomonas vaginalis: Atypical Multifunctional ProteinsThe late-annotated small ORF LSO1 is a target gene of the iron regulon of Saccharomyces cerevisiae.Cellular iron depletion and the mechanisms involved in the iron-dependent regulation of the growth arrest and DNA damage family of genesQuantitative analysis of the anti-proliferative activity of combinations of selected iron-chelating agents and clinically used anti-neoplastic drugsNeural and oligodendrocyte progenitor cells: transferrin effects on cell proliferationIron control of erythroid development by a novel aconitase-associated regulatory pathway.Eltrombopag inhibits the proliferation of leukemia cells via reduction of intracellular iron and induction of differentiationThe Eltrombopag antitumor effect on hepatocellular carcinoma.Targeting iron homeostasis induces cellular differentiation and synergizes with differentiating agents in acute myeloid leukemia.HIV-1 Rev-binding protein accelerates cellular uptake of iron to drive Notch-induced T cell leukemogenesis in miceEssential functions of iron-requiring proteins in DNA replication, repair and cell cycle control.Bacterial siderophores that evade or overwhelm lipocalin 2 induce hypoxia inducible factor 1α and proinflammatory cytokine secretion in cultured respiratory epithelial cells.Iron chelators of the di-2-pyridylketone thiosemicarbazone and 2-benzoylpyridine thiosemicarbazone series inhibit HIV-1 transcription: identification of novel cellular targets--iron, cyclin-dependent kinase (CDK) 2, and CDK9N-myc downstream regulated 1 (NDRG1) is regulated by eukaryotic initiation factor 3a (eIF3a) during cellular stress caused by iron depletion."Function-first" lead discovery: mode of action profiling of natural product libraries using image-based screeningCellular iron depletion stimulates the JNK and p38 MAPK signaling transduction pathways, dissociation of ASK1-thioredoxin, and activation of ASK1.Iron homeostasis and tumorigenesis: molecular mechanisms and therapeutic opportunitiesMitochondrial ferritin, a new target for inhibiting neuronal tumor cell proliferation.Bp44mT: an orally active iron chelator of the thiosemicarbazone class with potent anti-tumour efficacy.Iron chelators ICL670 and 311 inhibit HIV-1 transcription.Targeting cancer by binding iron: Dissecting cellular signaling pathwaysFerritin stimulates oligodendrocyte genesis in the adult spinal cord and can be transferred from macrophages to NG2 cells in vivoDifferential targeting of the cyclin-dependent kinase inhibitor, p21CIP1/WAF1, by chelators with anti-proliferative activity in a range of tumor cell-types.Iron-independent phosphorylation of iron regulatory protein 2 regulates ferritin during the cell cycleIron deprivation in cancer--potential therapeutic implicationsIron depletion enhances the effect of sorafenib in hepatocarcinomaOptimizing therapy for iron overload in the myelodysplastic syndromes: recent developments.Iron overload and allogeneic hematopoietic stem-cell transplantation.Thiosemicarbazones: the new wave in cancer treatment.The management of iron overload in allogeneic hematopoietic stem cell transplant (alloHSCT) recipients: where do we stand?The exochelins of pathogenic mycobacteria: unique, highly potent, lipid- and water-soluble hexadentate iron chelators with multiple potential therapeutic uses.Iron and colorectal cancer: evidence from in vitro and animal studies.Two cell cycle blocks caused by iron chelation of neuroblastoma cells: separating cell cycle events associated with each block.The Iron Chelator, Dp44mT, Effectively Inhibits Human Oral Squamous Cell Carcinoma Cell Growth in Vitro and in Vivo.Iron chelation therapy in low risk myelodysplastic syndrome.The iron chelators Dp44mT and DFO inhibit TGF-β-induced epithelial-mesenchymal transition via up-regulation of N-Myc downstream-regulated gene 1 (NDRG1).Iron depletion results in Src kinase inhibition with associated cell cycle arrest in neuroblastoma cells.Iron chelation: deciphering novel molecular targets for cancer therapy. The tip of the iceberg of a web of iron-regulated molecules.The oral iron chelator deferasirox represses signaling through the mTOR in myeloid leukemia cells by enhancing expression of REDD1.Iron chelator-induced apoptosis via the ER stress pathway in gastric cancer cells.
P2860
Q26771978-FFAFA294-2162-4303-A432-033112FF4F07Q27937450-4717D31B-CFE3-4790-924D-4575161BB494Q28392750-6EF0E431-909A-434C-8870-4077A4B55325Q28539989-72129159-1CFA-43C9-BECB-31C38E1A85DDQ28582481-28703D65-E2EB-4772-A06C-D53EDA79ED2AQ30431455-D6564C68-C14E-42CA-893F-A93577F1F49DQ33401421-FC1F2497-F333-4896-B57D-21CBBEAD4CC9Q33426135-FC1EB86C-B830-48B6-BBA8-06992BD2E0E0Q33795018-A7CEE695-B201-4E13-A0FC-74705BC131A7Q33968044-890DC1BE-BFC9-4614-9916-8F6CE4E184E9Q34268913-AB0CFE2E-3101-4D47-B1BD-C475D208DA58Q34298407-C2DE658A-8565-43B0-BC39-315CEDEEA836Q34458484-65F9AFED-9006-40C8-9E74-C42FBE38CEFAQ34600331-7AE5DDB0-5472-4AEE-A1A0-DB8D425D536BQ34601049-5C72A6A5-3A83-4680-A7F6-5B83728C1127Q34869589-0134B8BC-2C26-4C2A-B204-4C6D927A7184Q35034547-2328040E-8A0F-4809-AF69-D9684D4D53A9Q35069781-75BCC89F-C06E-43F3-A274-81394CC059A1Q35657936-3C188159-C3A5-4C1B-BFC4-BB0754ED10F6Q36143645-F9B282D2-E7F1-4F7F-AB9B-3F5A02B6FDF0Q36326247-0B4DCF1B-34A7-4A91-8A79-DC0B7D01CD12Q36464868-E41F48DA-56EF-471E-B49F-F91C89C31A1CQ36557412-0C313B88-4F5D-45A6-9292-7AED0FFF3257Q36855783-89BBD79C-903C-492C-AF17-77B390CDEC4AQ37177365-096DC412-B16E-4D81-8A12-56CF009BAC37Q37187753-F52B1798-D513-4D3E-A1F3-D6DAC3EEF3BCQ37833060-113918A3-3874-4FC1-9338-BFF8006542DBQ37842351-58780831-7318-43B0-AC8C-ECCFE85CB481Q37855829-939BAF94-4606-4296-BD0A-851B1C7351DFQ38083570-C2E8C4EF-119D-44F6-BBBC-059084F32ED4Q38200693-5DA90633-69CB-465E-8921-B482A50EA0ABQ38503037-12C9966C-20AD-4A72-8C12-FB4376D8B1B9Q38568878-DE18AC73-43F4-4D5A-ACB2-4E23521D161DQ38748533-0D25402D-E450-4662-86D3-915C34C50BCEQ38903926-59061285-8D30-405F-96F1-B26009A7E2A7Q39372971-12DF6D50-C631-4EA6-B554-C3EB048EDD0AQ39508428-13D0FF29-32E6-4A27-B64C-DC4EB57C272CQ39685368-ECE98CDB-30AD-4373-BDA4-76E514FD5050Q39870984-9E090AFF-D48B-4B92-A5B8-766F683D72A3Q40068994-50E2E730-8AE1-4D24-B72F-C4C2DE38CF52
P2860
Iron chelation and regulation of the cell cycle: 2 mechanisms of posttranscriptional regulation of the universal cyclin-dependent kinase inhibitor p21CIP1/WAF1 by iron depletion.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Iron chelation and regulation ...... 21CIP1/WAF1 by iron depletion.
@en
type
label
Iron chelation and regulation ...... 21CIP1/WAF1 by iron depletion.
@en
prefLabel
Iron chelation and regulation ...... 21CIP1/WAF1 by iron depletion.
@en
P1433
P1476
Iron chelation and regulation ...... 21CIP1/WAF1 by iron depletion.
@en
P2093
P304
P356
10.1182/BLOOD-2007-03-076737
P407
P577
2007-04-11T00:00:00Z