p53 modulates homologous recombination by transcriptional regulation of the RAD51 gene.
about
The transcription factor p53: not a repressor, solely an activatorThe molecular fingerprint of high grade serous ovarian cancer reflects its fallopian tube originTranscriptional regulation of human DNA repair genes following genotoxic stress: trigger mechanisms, inducible responses and genotoxic adaptationAcetylation of lysine 382 and phosphorylation of serine 392 in p53 modulate the interaction between p53 and MDC1 in vitrop53 in the DNA-Damage-Repair ProcessPreclinical study of the DNA repair inhibitor Dbait in combination with chemotherapy in colorectal cancerThe consequences of Rad51 overexpression for normal and tumor cellsRAD51 protein expression is increased in canine mammary carcinomasIn Vivo Delivery of miR-34a Sensitizes Lung Tumors to Radiation Through RAD51 RegulationOverexpression of RAD51 suppresses recombination defects: a possible mechanism to reverse genomic instability.p63 and p73 transcriptionally regulate genes involved in DNA repair.Cellular redistribution of Rad51 in response to DNA damage: novel role for Rad51C.Poly (ADP-ribose) polymerase inhibitor: an evolving paradigm in the treatment of prostate cancer.Redox regulation of DNA repair: implications for human health and cancer therapeutic development.Rad51 supports triple negative breast cancer metastasis.Regulation of Rad51 promoter.Adenoviral vector driven by a minimal Rad51 promoter is selective for p53-deficient tumor cells.RAD51B Activity and Cell Cycle Regulation in Response to DNA Damage in Breast Cancer Cell Lines.Profiling dose-dependent activation of p53-mediated signaling pathways by chemicals with distinct mechanisms of DNA damageAlterations in DNA repair gene expression and their possible regulation in rat-liver regeneration.Role of lamin b1 in chromatin instabilityp53 isoform Δ113p53/Δ133p53 promotes DNA double-strand break repair to protect cell from death and senescence in response to DNA damagePharmacological inhibition of Mdm2 triggers growth arrest and promotes DNA breakage in mouse colon tumors and human colon cancer cellsPoly(ADP-ribose) polymerase inhibition enhances p53-dependent and -independent DNA damage responses induced by DNA damaging agent.APE1/Ref-1 role in redox signaling: translational applications of targeting the redox function of the DNA repair/redox protein APE1/Ref-1.Polymorphism within the distal RAD51 gene promoter is associated with colorectal cancer in a Polish population.Analysis of hepatic transcript profile and plasma lipid profile in early lactating dairy cows fed grape seed and grape marc meal extract.Essential roles of Jab1 in cell survival, spontaneous DNA damage and DNA repairSuppression of Jab1/CSN5 induces radio- and chemo-sensitivity in nasopharyngeal carcinoma through changes to the DNA damage and repair pathwaysReplicational stress selects for p53 mutationAlterations of DNA damage repair pathways resulting from JCV infection.Genistein sensitizes sarcoma cells in vitro and in vivo by enhancing apoptosis and by inhibiting DSB repair pathwaysUse of the Rad51 promoter for targeted anti-cancer therapyVersatile functions of p53 protein in multicellular organismsp53 suppresses hyper-recombination by modulating BRCA1 function.The ubiquitin-proteasome system in cancer, a major player in DNA repair. Part 2: transcriptional regulationUrsolic Acid-Regulated Energy Metabolism-Reliever or Propeller of Ultraviolet-Induced Oxidative Stress and DNA Damage?One function--multiple mechanisms: the manifold activities of p53 as a transcriptional repressor.DNA double-strand break repair as determinant of cellular radiosensitivity to killing and target in radiation therapy.Modulation of homology-directed repair in T98G glioblastoma cells due to interactions between wildtype p53, Rad51 and HCMV IE1-72.
P2860
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P2860
p53 modulates homologous recombination by transcriptional regulation of the RAD51 gene.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
p53 modulates homologous recombination by transcriptional regulation of the RAD51 gene.
@en
type
label
p53 modulates homologous recombination by transcriptional regulation of the RAD51 gene.
@en
prefLabel
p53 modulates homologous recombination by transcriptional regulation of the RAD51 gene.
@en
P2093
P2860
P356
P1433
P1476
p53 modulates homologous recombination by transcriptional regulation of the RAD51 gene.
@en
P2093
Augusto Silva
Carmen Arias-Lopez
Iciar Lazaro-Trueba
Marjan Iravani
Peter Kerr
Tim Dexter
P2860
P304
P356
10.1038/SJ.EMBOR.7400587
P577
2006-02-01T00:00:00Z