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Human Rad50 is physically associated with human Mre11: identification of a conserved multiprotein complex implicated in recombinational DNA repairFanconi anemia proteins FANCA, FANCC, and FANCG/XRCC9 interact in a functional nuclear complexhMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaksCrystal Structure of MutS2 Endonuclease Domain and the Mechanism of Homologous Recombination SuppressionMutations in two Ku homologs define a DNA end-joining repair pathway in Saccharomyces cerevisiaeUp-regulation of DNA-dependent protein kinase correlates with radiation resistance in oral squamous cell carcinomaKu70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombinationBinding of Ku and c-Abl at the kinase homology region of DNA-dependent protein kinase catalytic subunitConditional gene targeted deletion by Cre recombinase demonstrates the requirement for the double-strand break repair Mre11 protein in murine embryonic stem cellsNo requirement for V(D)J recombination in p53-deficient thymic lymphomaHomologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cellsRegulation of DNA-dependent protein kinase by the Lyn tyrosine kinase.Computational analysis of retrovirus-induced scid cell death.Hypersensitivity of Ku80-deficient cell lines and mice to DNA damage: the effects of ionizing radiation on growth, survival, and development.In vitro repair of gaps in bacteriophage T7 DNA.Inactivation of DNA-dependent protein kinase by protein kinase Cdelta: implications for apoptosisRecombinational repair in yeast: functional interactions between Rad51 and Rad54 proteins.Ku protein stimulates DNA end joining by mammalian DNA ligases: a direct role for Ku in repair of DNA double-strand breaks.Transposase makes critical contacts with, and is stimulated by, single-stranded DNA at the P element termini in vitro.Mitotic recombination in yeast: elements controlling its incidence.Sister chromatid exchanges are mediated by homologous recombination in vertebrate cells.DNA damage-dependent nuclear dynamics of the Mre11 complexVisualization of repair of double-strand breaks in the bacteriophage T7 genome without normal DNA replication.A comprehensive continuous-time model for the appearance of CGH signal due to chromosomal missegregations during mitosis.MDC1 interacts with Rad51 and facilitates homologous recombination.Topoisomerase poisons activate the transcription factor NF-kappaB in ACH-2 and CEM cells.Enhancer control of V(D)J recombination at the TCRbeta locus: differential effects on DNA cleavage and joining.DNA double-strand-break sensitivity, DNA replication, and cell cycle arrest phenotypes of Ku-deficient Saccharomyces cerevisiaeKu70 is required for DNA repair but not for T cell antigen receptor gene recombination In vivo.A basic motif in the N-terminal region of RAG1 enhances V(D)J recombination activity.Enhancer control of local accessibility to V(D)J recombinase.The Drosophila melanogaster RAD54 homolog, DmRAD54, is involved in the repair of radiation damage and recombination.V(D)J recombination: in vitro coding joint formation.Ku70/80 gene expression and DNA-dependent protein kinase (DNA-PK) activity do not correlate with double-strand break (dsb) repair capacity and cellular radiosensitivity in normal human fibroblasts.A coumarin derivative (RKS262) inhibits cell-cycle progression, causes pro-apoptotic signaling and cytotoxicity in ovarian cancer cells.p53 C-terminal interaction with DNA ends and gaps has opposing effect on specific DNA binding by the core.Disruption of ATM in p53-null cells causes multiple functional abnormalities in cellular response to ionizing radiation.OBA/Ku86: DNA binding specificity and involvement in mammalian DNA replicationRequirement of wild-type p53 protein for maintenance of chromosomal integrity.Homologous recombination and DNA-end joining reactions in zygotes and early embryos of zebrafish (Danio rerio) and Drosophila melanogaster.
P2860
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P2860
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
What to do at an end: DNA double-strand-break repair.
@en
type
label
What to do at an end: DNA double-strand-break repair.
@en
prefLabel
What to do at an end: DNA double-strand-break repair.
@en
P1433
P1476
What to do at an end: DNA double-strand-break repair.
@en
P2093
P304
P356
10.1016/S0168-9525(00)89121-0
P577
1995-10-01T00:00:00Z