Accessibility of mid-segment domain IV S6 residues of the voltage-gated Na+ channel to methanethiosulfonate reagents.
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Voltage-gated sodium channel-associated proteins and alternative mechanisms of inactivation and blockA homology model of the pore domain of a voltage-gated calcium channel is consistent with available SCAM data.Tryptophan substitution of a putative D4S6 gating hinge alters slow inactivation in cardiac sodium channels.Molecular determinants of state-dependent block of voltage-gated sodium channels by pilsicainide.Important Role of Asparagines in Coupling the Pore and Votage-Sensor Domain in Voltage-Gated Sodium Channels.Multiple pore conformations driven by asynchronous movements of voltage sensors in a eukaryotic sodium channelThe external pore loop interacts with S6 and S3-S4 linker in domain 4 to assume an essential role in gating control and anticonvulsant action in the Na(+) channelUsing lidocaine and benzocaine to link sodium channel molecular conformations to state-dependent antiarrhythmic drug affinity.Evolutionarily conserved intracellular gate of voltage-dependent sodium channels.Charge at the lidocaine binding site residue Phe-1759 affects permeation in human cardiac voltage-gated sodium channels.Isoform-dependent interaction of voltage-gated sodium channels with protons.A molecular model of the inner pore of the Ca channel in its open state.Physiological and pharmacologic aspects of peripheral nerve blocksInhibition of Sodium Ion Channel Function with Truncated Forms of Batrachotoxin.Congruent pattern of accessibility identifies minimal pore gate in a non-symmetric voltage-gated sodium channelMolecular basis for class Ib anti-arrhythmic inhibition of cardiac sodium channels.A point mutation at F1737 of the human Nav1.7 sodium channel decreases inhibition by local anesthetics.Gating of the kir2.1 channel at the bundle crossing region by intracellular spermine and other cations.
P2860
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P2860
Accessibility of mid-segment domain IV S6 residues of the voltage-gated Na+ channel to methanethiosulfonate reagents.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
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2004年學術文章
@zh-hant
name
Accessibility of mid-segment d ...... methanethiosulfonate reagents.
@en
type
label
Accessibility of mid-segment d ...... methanethiosulfonate reagents.
@en
prefLabel
Accessibility of mid-segment d ...... methanethiosulfonate reagents.
@en
P2093
P2860
P1476
Accessibility of mid-segment d ...... methanethiosulfonate reagents.
@en
P2093
Akihiko Sunami
Arlene Tracey
Dorothy A Hanck
Gregory M Lipkind
Harry A Fozzard
Ian W Glaaser
P2860
P304
P356
10.1113/JPHYSIOL.2004.067579
P407
P577
2004-10-07T00:00:00Z