Tel induces a G1 arrest and suppresses Ras-induced transformation.
about
Identification of a novel fusion gene, TTL, fused to ETV6 in acute lymphoblastic leukemia with t(12;13)(p13;q14), and its implication in leukemogenesis.Small ubiquitin-like modifier conjugation regulates nuclear export of TEL, a putative tumor suppressorOrigins of chromosome translocations in childhood leukaemia.The ETS factor TEL2 is a hematopoietic oncoprotein.Common genetic variation in ETV6 is associated with colorectal cancer susceptibilityMechanisms of transcription factor deregulation in lymphoid cell transformation.Genetic abnormalities involved in t(12;21) TEL-AML1 acute lymphoblastic leukemia: analysis by means of array-based comparative genomic hybridization.Identification of transcripts modulated by ETV6 expression.TEL/ETV6 is a signal transducer and activator of transcription 3 (Stat3)-induced repressor of Stat3 activity.Mechanism of ETV6-RUNX1 Leukemia.Leukemia-related transcription factor TEL is negatively regulated through extracellular signal-regulated kinase-induced phosphorylationComparative analysis of the ETV6 gene in vertebrate genomes from pufferfish to human.TEL, a putative tumor suppressor, induces apoptosis and represses transcription of Bcl-XL.v-SRC specifically regulates the nucleo-cytoplasmic delocalization of the major isoform of TEL (ETV6).TEL contacts multiple co-repressors and specifically associates with histone deacetylase-3.Disruption of ETV6 leads to TWIST1-dependent progression and resistance to epidermal growth factor receptor tyrosine kinase inhibitors in prostate cancer.Sumoylation and Its Contribution to Cancer.Native ETV6 deletions accompanied by ETV6-RUNX1 rearrangements are associated with a favourable prognosis in childhood acute lymphoblastic leukaemia: a candidate for prognostic marker.
P2860
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P2860
Tel induces a G1 arrest and suppresses Ras-induced transformation.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
@zh
2000年學術文章
@zh-hant
name
Tel induces a G1 arrest and suppresses Ras-induced transformation.
@en
type
label
Tel induces a G1 arrest and suppresses Ras-induced transformation.
@en
prefLabel
Tel induces a G1 arrest and suppresses Ras-induced transformation.
@en
P2093
P2860
P356
P1433
P1476
Tel induces a G1 arrest and suppresses Ras-induced transformation.
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1203899
P407
P577
2000-11-01T00:00:00Z
P5875
P6179
1040602635