IPF1, a homeodomain-containing transactivator of the insulin gene.
about
Neuroendocrine differentiation factor, IA-1, is a transcriptional repressor and contains a specific DNA-binding domain: identification of consensus IA-1 binding sequenceIdentification of beta-cell-specific insulin gene transcription factor RIPE3b1 as mammalian MafA.Conserved sequences in a tissue-specific regulatory region of the pdx-1 gene mediate transcription in Pancreatic beta cells: role for hepatocyte nuclear factor 3 beta and Pax6Insulin gene transcription is mediated by interactions between the p300 coactivator and PDX-1, BETA2, and E47.The p48 DNA-binding subunit of transcription factor PTF1 is a new exocrine pancreas-specific basic helix-loop-helix proteinMissense mutations in the insulin promoter factor-1 gene predispose to type 2 diabetesIdentification of PCIF1, a POZ domain protein that inhibits PDX-1 (MODY4) transcriptional activityNotch signaling controls multiple steps of pancreatic differentiationThe bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreasThe MafA transcription factor appears to be responsible for tissue-specific expression of insulinneurogenin3 is required for the development of the four endocrine cell lineages of the pancreasPurification of the beta-cell glucose-sensitive factor that transactivates the insulin gene differentially in normal and transformed islet cellsFoxA2, Nkx2.2, and PDX-1 regulate islet beta-cell-specific mafA expression through conserved sequences located between base pairs -8118 and -7750 upstream from the transcription start sitePancreatic-duodenal homeobox 1 regulates expression of liver receptor homolog 1 during pancreas developmentRole of AMP-activated protein kinase in the regulation by glucose of islet beta cell gene expressionIncreased islet apoptosis in Pdx1+/- miceMechanisms of action of glucagon-like peptide 1 in the pancreasPancreatic Cancer GeneticsHedgehog Signaling in Pancreatic Fibrosis and CancerEpidemiology and Inherited Predisposition for Sporadic Pancreatic AdenocarcinomaSwertisin an Anti-Diabetic Compound Facilitate Islet Neogenesis from Pancreatic Stem/Progenitor Cells via p-38 MAP Kinase-SMAD Pathway: An In-Vitro and In-Vivo StudyUtilizing past and present mouse systems to engineer more relevant pancreatic cancer modelsGhrelin cells replace insulin-producing beta cells in two mouse models of pancreas developmentDevelopment of diabetes mellitus in aging transgenic mice following suppression of pancreatic homeoprotein IDX-1Gata6 is an important regulator of mouse pancreas developmentThe Krüppel-like zinc finger protein Glis3 directly and indirectly activates insulin gene transcriptionMembers of the large Maf transcription family regulate insulin gene transcription in islet beta cellsInsm1 promotes endocrine cell differentiation by modulating the expression of a network of genes that includes Neurog3 and Ripply3The pancreatic islet factor STF-1 binds cooperatively with Pbx to a regulatory element in the somatostatin promoter: importance of the FPWMK motif and of the homeodomainPDX:PBX complexes are required for normal proliferation of pancreatic cells during developmentTargeted deletion of a cis-regulatory region reveals differential gene dosage requirements for Pdx1 in foregut organ differentiation and pancreas formation.Genomic organisation of the seven ParaHox genes of coelacanthsPdx1 is post-translationally modified in vivo and serine 61 is the principal site of phosphorylationPdx1 and Ngn3 overexpression enhances pancreatic differentiation of mouse ES cell-derived endoderm populationPancreatic beta cells require NeuroD to achieve and maintain functional maturityMethyltransferase Set7/9 maintains transcription and euchromatin structure at islet-enriched genesA feat of metabolic proportions: Pdx1 orchestrates islet development and function in the maintenance of glucose homeostasis.Functional evaluation of ES cell-derived endodermal populations reveals differences between Nodal and Activin A-guided differentiation.Urocortin 3 marks mature human primary and embryonic stem cell-derived pancreatic alpha and beta cellsAn endocrine-exocrine switch in the activity of the pancreatic homeodomain protein PDX1 through formation of a trimeric complex with PBX1b and MRG1 (MEIS2).
P2860
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P2860
IPF1, a homeodomain-containing transactivator of the insulin gene.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh
1993年學術文章
@zh-hant
name
IPF1, a homeodomain-containing transactivator of the insulin gene.
@en
type
label
IPF1, a homeodomain-containing transactivator of the insulin gene.
@en
prefLabel
IPF1, a homeodomain-containing transactivator of the insulin gene.
@en
P2093
P2860
P1433
P1476
IPF1, a homeodomain-containing transactivator of the insulin gene.
@en
P2093
P2860
P304
P407
P577
1993-11-01T00:00:00Z