Accumulation of cyclin B1 requires E2F and cyclin-A-dependent rearrangement of the anaphase-promoting complex.
about
Cyclin A2 mutagenesis analysis: a new insight into CDK activation and cellular localization requirementsThe function of APC/CCdh1 in cell cycle and beyondMale germ cell-associated kinase is overexpressed in prostate cancer cells and causes mitotic defects via deregulation of APC/CCDH1The decision to enter mitosis: feedback and redundancy in the mitotic entry networkThe Cdc14B-Cdh1-Plk1 axis controls the G2 DNA-damage-response checkpointDifferential expression, localization and activity of two alternatively spliced isoforms of human APC regulator CDH1Timing of APC/C substrate degradation is determined by fzy/fzr specificity of destruction boxes.Securin degradation is mediated by fzy and fzr, and is required for complete chromatid separation but not for cytokinesisRegulation of late G1/S phase transition and APC Cdh1 by reactive oxygen speciesNonperiodic activity of the human anaphase-promoting complex-Cdh1 ubiquitin ligase results in continuous DNA synthesis uncoupled from mitosisMammalian Cdh1/Fzr mediates its own degradationE2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpointsMolecular functions of genes related to grain shape in riceFunctional characterization of Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesisDual control by Cdk1 phosphorylation of the budding yeast APC/C ubiquitin ligase activator Cdh1Atomic structure of the APC/C and its mechanism of protein ubiquitination.Mitosis in neurons: Roughex and APC/C maintain cell cycle exit to prevent cytokinetic and axonal defects in Drosophila photoreceptor neuronsThe Ubp15 deubiquitinase promotes timely entry into S phase in Saccharomyces cerevisiaeEarly expressed Clb proteins allow accumulation of mitotic cyclin by inactivating proteolytic machinery during S phaseAPC/C and retinoblastoma interaction: cross-talk of retinoblastoma protein with the ubiquitin proteasome pathwayGetting to S: CDK functions and targets on the path to cell-cycle commitmentRegulation of the anaphase-promoting complex by the dual specificity phosphatase human Cdc14aPathways governing G1/S transition and their response to DNA damageNuclear localization of the cell cycle regulator CDH1 and its regulation by phosphorylationThe DNA damage response mediator MDC1 directly interacts with the anaphase-promoting complex/cyclosomeCyclin A/cdk2 coordinates centrosomal and nuclear mitotic eventsEmi1 regulates the anaphase-promoting complex by a different mechanism than Mad2 proteinsPhosphorylation-dependent and -independent functions of p130 cooperate to evoke a sustained G1 block.Activation of Cdh1-dependent APC is required for G1 cell cycle arrest and DNA damage-induced G2 checkpoint in vertebrate cellsTumor suppressors and cell-cycle proteins in lung cancerMitotic regulation of the APC activator proteins CDC20 and CDH1The APC/C inhibitor, Emi1, is essential for prevention of rereplicationEmi1 is needed to couple DNA replication with mitosis but does not regulate activation of the mitotic APC/CCyclin E overexpression impairs progression through mitosis by inhibiting APC(Cdh1).Atypical E2F activity restrains APC/CCCS52A2 function obligatory for endocycle onsetRetinoblastoma tumor suppressor protein signals through inhibition of cyclin-dependent kinase 2 activity to disrupt PCNA function in S phase.A role for the START gene-specific transcription factor complex in the inactivation of cyclin B and Cut2 destructionRegulation of APC/C activators in mitosis and meiosis.S and G2 phase roles for Cdk2 revealed by inducible expression of a dominant-negative mutant in human cells.Regulation and roles of Cdc7 kinase under replication stress.
P2860
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P2860
Accumulation of cyclin B1 requires E2F and cyclin-A-dependent rearrangement of the anaphase-promoting complex.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Accumulation of cyclin B1 requ ...... he anaphase-promoting complex.
@en
type
label
Accumulation of cyclin B1 requ ...... he anaphase-promoting complex.
@en
prefLabel
Accumulation of cyclin B1 requ ...... he anaphase-promoting complex.
@en
P2093
P50
P356
P1433
P1476
Accumulation of cyclin B1 requ ...... he anaphase-promoting complex.
@en
P2093
C Lindeneg
C S Sørensen
E Santoni-Rugiu
J M Peters
P2888
P304
P356
10.1038/44611
P407
P577
1999-10-01T00:00:00Z
P6179
1049927269