Rapid activation and nuclear translocation of mitogen-activated protein kinases in response to physiological concentration of glucose in the MIN6 pancreatic beta cell line.
about
Extracellular regulated kinases (ERK) 1 and ERK2 are authentic substrates for the dual-specificity protein-tyrosine phosphatase VHR. A novel role in down-regulating the ERK pathwayMechanisms of estradiol-induced insulin secretion by the G protein-coupled estrogen receptor GPR30/GPER in pancreatic beta-cellsGlucose induced MAPK signalling influences NeuroD1-mediated activation and nuclear localizationNifedipine suppresses neointimal thickening by its inhibitory effect on vascular smooth muscle cell growth via a MEK-ERK pathway coupling with Pyk2Dynamic changes in the localization of MAPK cascade components controlling pathogenesis-related (PR) gene expression during innate immunity in parsley.L-histidine sensing by calcium sensing receptor inhibits voltage-dependent calcium channel activity and insulin secretion in β-cells.Acute insulin signaling in pancreatic beta-cells is mediated by multiple Raf-1 dependent pathwaysEGF regulates survivin stability through the Raf-1/ERK pathway in insulin-secreting pancreatic β-cells.Isoproterenol and cAMP block ERK phosphorylation and enhance [Ca2+]i increases and oxygen consumption by muscarinic receptor stimulation in rat parotid and submandibular acinar cells.Communication between the cell membrane and the nucleus: role of protein compartmentalization.Evidence that Ca2+ within the microdomain of the L-type voltage gated Ca2+ channel activates ERK in MIN6 cells in response to glucagon-like peptide-1.Quercetin potentiates insulin secretion and protects INS-1 pancreatic β-cells against oxidative damage via the ERK1/2 pathway.Targeting beta-cell cyclic 3'5' adenosine monophosphate for the development of novel drugs for treating type 2 diabetes mellitus. A review.Beta cells in type 2 diabetes - a crucial contribution to pathogenesis.Glucose and GLP-1 stimulate cAMP production via distinct adenylyl cyclases in INS-1E insulinoma cells.The roles of MAPKs in disease.Involvement of Per-Arnt-Sim Kinase and extracellular-regulated kinases-1/2 in palmitate inhibition of insulin gene expression in pancreatic beta-cells.Off-target effects of MEK inhibitorsGlucose activates mitogen-activated protein kinase (extracellular signal-regulated kinase) through proline-rich tyrosine kinase-2 and the Glut1 glucose transporter.GRFbeta, a novel regulator of calcium signaling, is expressed in pancreatic beta cells and brain.beta-Arrestin 1 is required for PAC1 receptor-mediated potentiation of long-lasting ERK1/2 activation by glucose in pancreatic beta-cells.Glucagon promotes cAMP-response element-binding protein phosphorylation via activation of ERK1/2 in MIN6 cell line and isolated islets of Langerhans.Exendin-4 as a stimulator of rat insulin I gene promoter activity via bZIP/CRE interactions sensitive to serine/threonine protein kinase inhibitor Ro 31-8220.Mode of regulation of the extracellular signal-regulated kinases in the pancreatic beta-cell line MIN6 and their implication in the regulation of insulin gene transcription.Evidence against high glucose as a mediator of ERK1/2 or p38 MAPK phosphorylation in rat skeletal muscle.ERK1 is dispensable for mouse pancreatic beta cell function but is necessary for glucose-induced full activation of MSK1 and CREB.
P2860
Q28142838-A9363DBB-DBD0-4578-B1E7-86A6BEBE2932Q28506684-52DFAF92-DA0C-4CDA-91F0-0FDC5E08EC17Q28566461-30F3204C-DCA7-4035-A1A3-37F350AD3E6BQ28578027-AA073927-4987-475C-8A1F-06410F8A16EDQ30320520-25410B43-024C-422E-951B-F150C52D38D0Q30995556-988D7FB3-2839-4B98-A9E7-1E55CEAB3321Q33634298-DA659AAC-CE36-430F-ACFB-5A2A21FF5BB9Q33679446-2CA4DD39-184B-4144-8962-AF827F315CC2Q33809881-A6C001CB-F19C-45E7-9D7F-1FEB42313B3BQ34103406-1876166B-9B66-4BDF-8A12-8969BE9D9665Q34193626-A44A1BDE-7AE3-40F3-B1BB-660AD25C814FQ34356099-A99B1381-843D-460F-AA88-2793717864DFQ35962745-B0C0FE66-992F-492C-8513-B93BBB8DAF2DQ36798634-E3DF0DC7-B631-49AA-AF96-EC30EFDAB050Q36843192-F3E9596E-825C-4DF5-A3EC-06CD6AA64C05Q37112520-C197138A-A109-41A5-B2A3-3F7C18408662Q37317469-9AEB1E2C-616E-462C-946B-5EB5162E1151Q37385007-A633011F-0CF3-409E-925E-FE97114828F9Q38308025-DBBE818E-CC60-4508-98C5-F41B93F50829Q38321363-BC36B594-65BC-44CC-A322-1C49936144CEQ39906419-2E65CD19-DB7C-49F6-9D8A-0E6C96F6B07BQ40584918-CA4D4A9E-D0AF-4A5D-8406-EC86BBB6B7D4Q40731281-9BE144BF-F4EE-4E9B-B330-5FD85EBE862BQ40956369-E6D356B4-8F40-4E14-B371-9B87664BDC10Q43794384-1B04F136-BF9F-49FF-9B0F-D8CA0FCD89D3Q50882981-73938C78-78A1-452E-AD48-A72EE61BA4E1
P2860
Rapid activation and nuclear translocation of mitogen-activated protein kinases in response to physiological concentration of glucose in the MIN6 pancreatic beta cell line.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Rapid activation and nuclear t ...... IN6 pancreatic beta cell line.
@en
type
label
Rapid activation and nuclear t ...... IN6 pancreatic beta cell line.
@en
prefLabel
Rapid activation and nuclear t ...... IN6 pancreatic beta cell line.
@en
P2093
P2860
P356
P1476
Rapid activation and nuclear t ...... MIN6 pancreatic beta cell line
@en
P2093
P2860
P304
15507-15513
P356
10.1074/JBC.273.25.15507
P407
P577
1998-06-01T00:00:00Z