Gp130-mediated signal transduction in embryonic stem cells involves activation of Jak and Ras/mitogen-activated protein kinase pathways.
about
Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathwaySelf-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3Removal of LIF (leukemia inhibitory factor) results in increased vitamin A (retinol) metabolism to 4-oxoretinol in embryonic stem cellsEx uno plures: molecular designs for embryonic pluripotencyLeukemia inhibitory factor (LIF)Distinct roles for leukemia inhibitory factor receptor alpha-chain and gp130 in cell type-specific signal transductionAn extended transcriptional network for pluripotency of embryonic stem cellsKos1, a nonreceptor tyrosine kinase that suppresses Ras signalingRole of cytokine signaling during nervous system developmentStat3: linking inflammation to epithelial cancer - more than a "gut" feeling?LIF-independent JAK signalling to chromatin in embryonic stem cells uncovered from an adult stem cell disease.What does Stat3 do?Essential role of STAT3 for embryonic stem cell pluripotencyImproving embryonic stem cell expansion through the combination of perfusion and Bioprocess model design.Oncostatin M promotes mucosal epithelial barrier dysfunction, and its expression is increased in patients with eosinophilic mucosal diseaseHematopoietic cell kinase (HCK) as a therapeutic target in immune and cancer cells.Regulation of embryonic stem cell self-renewal and pluripotency by leukaemia inhibitory factorThe disparate role of BMP in stem cell biology.Leukemia inhibitory factor-dependent transcriptional activation in embryonic stem cells.Constitutive activation of the SRC family kinase Hck results in spontaneous pulmonary inflammation and an enhanced innate immune responseAssessment of bone dysplasia by micro-CT and glycosaminoglycan levels in mouse models for mucopolysaccharidosis type I, IIIA, IVA, and VIIMultivariate proteomic analysis of murine embryonic stem cell self-renewal versus differentiation signalingMu- and kappa-opioids induce the differentiation of embryonic stem cells to neural progenitors.Roles for MYC in the establishment and maintenance of pluripotency.Cyclin-dependent kinase 2-associating protein 1 commits murine embryonic stem cell differentiation through retinoblastoma protein regulation.The role of Krüppel-like factors in the reprogramming of somatic cells to induced pluripotent stem cells.The enigmatic cytokine oncostatin m and roles in diseaseMechanism of shortened bones in mucopolysaccharidosis VIIJAK-STAT3 and somatic cell reprogramming.Role of bioinspired polymers in determination of pluripotent stem cell fate.The Role of the Leukemia Inhibitory Factor (LIF) - Pathway in Derivation and Maintenance of Murine Pluripotent Stem Cells.Protein kinases and associated pathways in pluripotent state and lineage differentiation.Layered double hydroxide nanoparticles promote self-renewal of mouse embryonic stem cells through the PI3K signaling pathway.Promotion of self-renewal of embryonic stem cells by midkinePluripotency of a polyploid H1 (ES) cell system without leukaemia inhibitory factor.The barrier hypothesis and Oncostatin M: Restoration of epithelial barrier function as a novel therapeutic strategy for the treatment of type 2 inflammatory disease.Conserved regulation of the Jak/STAT pathway by the endosomal protein asrij maintains stem cell potency.Effect of leukemia inhibitory factor on embryonic stem cell differentiation: implications for supporting neuronal differentiation.Activation of the Stat3 signaling pathway is required for differentiation by interleukin-6 in PC12-E2 cells.Multiple myeloma: increasing evidence for a multistep transformation process.
P2860
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P2860
Gp130-mediated signal transduction in embryonic stem cells involves activation of Jak and Ras/mitogen-activated protein kinase pathways.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Gp130-mediated signal transduc ...... vated protein kinase pathways.
@en
type
label
Gp130-mediated signal transduc ...... vated protein kinase pathways.
@en
prefLabel
Gp130-mediated signal transduc ...... vated protein kinase pathways.
@en
P2093
P2860
P356
P1476
Gp130-mediated signal transduc ...... vated protein kinase pathways.
@en
P2093
P2860
P304
30136-30143
P356
10.1074/JBC.271.47.30136
P407
P577
1996-11-01T00:00:00Z