Quantitation of the frequency of immortalization of normal human diploid fibroblasts by SV40 large T-antigen.
about
Human telomerase and its regulationSmurf2 up-regulation activates telomere-dependent senescenceChromosome 7 suppresses indefinite division of nontumorigenic immortalized human fibroblast cell lines KMST-6 and SUSM-1p38alpha and p38gamma mediate oncogenic ras-induced senescence through differential mechanismsTelomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activitySuppression of hPOT1 in diploid human cells results in an hTERT-dependent alteration of telomere length dynamics.Alternative lengthening of telomeres can be maintained by preferential elongation of lagging strands.Role of telomerase in cellular proliferation and cancer.Alternative pathways for the extension of cellular life span: inactivation of p53/pRb and expression of telomerase.The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.Transformation of human and murine fibroblasts without viral oncoproteins.Telomerase extracurricular activities.Conversion of normal to malignant phenotype: telomere shortening, telomerase activation, and genomic instability during immortalization of human oral keratinocytes.Developmental and tissue-specific regulation of mouse telomerase and telomere length.Simian virus 40 small tumor antigen activates AKT and telomerase and induces anchorage-independent growth of human epithelial cellshTERT extends the life of human fibroblasts without compromising type I interferon signaling.Telomere maintenance and cancer -- look, no telomerase.Regulation of cellular senescence by the essential caveolar component PTRF/Cavin-1.Ink4a/Arf tumor suppressor does not modulate the degenerative conditions or tumor spectrum of the telomerase-deficient mouse.Surveillance mechanism linking Bub1 loss to the p53 pathway.Concepts of human leukemic development.Targeted deletion reveals an essential function for the telomere length regulator Trf1.Can ends justify the means?: telomeres and the mechanisms of replicative senescence and immortalization in mammalian cellsKaryotype alteration generates the neoplastic phenotypes of SV40-infected human and rodent cellsImmortalized cells as experimental models to study cancer.Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening.Spontaneous in vitro immortalization of breast epithelial cells from a patient with Li-Fraumeni syndromeStabilization of short telomeres and telomerase activity accompany immortalization of Epstein-Barr virus-transformed human B lymphocytesComparison of DNA methylation patterns among mouse cell lines by restriction landmark genomic scanningImmortality of cancers: a consequence of inherent karyotypic variations and selections for autonomy.Cell therapy for diabetes mellitus.Altered chromosome 6 in immortal human fibroblastsRole of Telomeres and Telomerase in Aging and Cancer.Artificial cells for the development of cell therapy.Induction of p38δ expression plays an essential role in oncogenic ras-induced senescenceSenescence delay and repression of p16INK4a by Lsh via recruitment of histone deacetylases in human diploid fibroblasts.Age-dependent alterations of c-fos and growth regulation in human fibroblasts expressing the HPV16 E6 protein.Chromatin and epigenetic regulation of the telomerase reverse transcriptase gene.Telomerase and its extracurricular activities.The hTERT gene is embedded in a nuclease-resistant chromatin domain.
P2860
Q24533247-136D7055-4C6C-4534-BF44-04F87D7C7672Q24558758-E6789EFC-D548-4158-AC31-7376CE783BAFQ24629799-35E4D796-AD21-4EAF-91D5-FD4D9DC76883Q24657888-4234257F-1C88-4807-8E00-C1BB2126507DQ29615388-47B6E484-39BA-4A7C-9500-8FF52C0793CAQ33376950-6BCCB9DA-EE70-48C0-B4AE-ED7B094C196AQ33558285-83344739-C288-429A-B665-877670FC27F7Q33653970-B5AD3F14-20C7-461D-BEEF-CEDD7D8F1FD6Q33807819-652DB8AF-D9AD-4B62-9A1E-BBE2BDE5A87DQ33889383-85603188-3E9C-41C2-B344-6C83FE69F33BQ33925306-C477C9D2-3767-4AE5-AE39-9387CA08A602Q34188137-4527AD94-3B3F-4BE1-B7E4-02241C755A1AQ34249547-F0C29E3E-26CD-48AF-8D53-7805E6929BB7Q34265760-CC317552-52BA-49FF-ADFB-FE7E4D0B0850Q34349115-C89748A1-317A-4824-9621-ADA52446B09AQ34614831-0A9F9753-6CFC-4BCB-912B-717BD45D7D6AQ34988280-7A671251-7B01-4BE0-B8B6-847E877E5ADFQ35348922-33639891-D855-4BCA-9042-FF4058EF1D31Q35676717-70FDCD6A-B07C-4235-974E-5281CD3DBFCAQ35850149-FB08EEA8-7DAC-4342-82DC-989932740BA3Q35892080-9044BE89-E57D-4E9E-B4B2-8415E1883434Q35920252-29BC44C9-13C5-4972-92EB-734784CE7F03Q36070936-F76ECA7A-D6A4-4DFD-96A5-B6AFBD2A604FQ36202215-ACC50E0E-4719-425C-A9B9-76680AD01114Q36255511-FC98C493-2377-4BC2-AD8A-763F6D56744DQ36449812-1DD2944A-7D21-43EA-9367-B1491B97427DQ36567058-EEEF1A5A-BEB8-4978-80D8-8182EA5C242EQ36633820-895E1694-1702-4023-A784-0AFF5D0AD76FQ36669714-04B7421A-33D0-4E69-8081-E1B40CC1E5A5Q36724281-29A42C37-1603-4AA5-974F-68584DE6B56DQ36735591-B7584545-D018-4475-91E6-466BEECEEC09Q36815171-DF9B5966-CCC0-4E87-959F-75A9055E5623Q36971261-D2F3E6E0-547E-4DFD-82E9-ABD6A565AAD0Q37158529-12A481B8-55DF-4E1E-9F86-784C54F12C90Q37264977-C9F3918F-CD95-4CDE-9049-009B4596A7F1Q37318496-3B3F5FB0-1AD5-487B-9790-62CB9C5AAAF3Q37381373-80A4627F-686D-4BD1-AB0E-3BDF9D22CFDDQ37825834-C03EAE08-2E69-459E-9005-3406FD944EBCQ38139289-25B9A565-1B8F-4452-A2C5-950221314CCEQ38334852-76BB1451-3F4B-439F-A880-FE312BC02A91
P2860
Quantitation of the frequency of immortalization of normal human diploid fibroblasts by SV40 large T-antigen.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
1989年论文
@zh
1989年论文
@zh-cn
name
Quantitation of the frequency ...... lasts by SV40 large T-antigen.
@en
type
label
Quantitation of the frequency ...... lasts by SV40 large T-antigen.
@en
prefLabel
Quantitation of the frequency ...... lasts by SV40 large T-antigen.
@en
P1476
Quantitation of the frequency ...... lasts by SV40 large T-antigen.
@en
P2093
P304
P356
10.1016/0014-4827(89)90369-8
P407
P577
1989-09-01T00:00:00Z