Activation of V kappa gene rearrangement in pre-B cells follows the expression of membrane-bound immunoglobulin heavy chains.
about
Immunoglobulin lambda light-chain-related genes 14.1 and 16.1 are expressed in pre-B cells and may encode the human immunoglobulin omega light-chain proteinDual role of the tyrosine activation motif of the Ig-alpha protein during signal transduction via the B cell antigen receptorMapping of sites on the Src family protein tyrosine kinases p55blk, p59fyn, and p56lyn which interact with the effector molecules phospholipase C-gamma 2, microtubule-associated protein kinase, GTPase-activating protein, and phosphatidylinositol 3-kRole of the Syk autophosphorylation site and SH2 domains in B cell antigen receptor signalingMolecular components of the B cell antigen receptor complex of class IgD differ partly from those of IgMIsolation of scid pre-B cells that rearrange kappa light chain genes: formation of normal signal and abnormal coding joinsLight-chain gene expression before heavy-chain gene rearrangement in pre-B cells transformed by Epstein-Barr virusMutations in Igalpha (CD79a) result in a complete block in B-cell development.Two types of mu chain complexes are expressed during differentiation from pre-B to mature B cellsDeletion of the immunoglobulin kappa chain intron enhancer abolishes kappa chain gene rearrangement in cis but not lambda chain gene rearrangement in transB-cell-lineage immunogen design in vaccine development with HIV-1 as a case studyB cell antigen receptor desensitization: disruption of receptor coupling to tyrosine kinase activationCis-regulatory elements and epigenetic changes control genomic rearrangements of the IgH locus.Distinct p53/56lyn and p59fyn domains associate with nonphosphorylated and phosphorylated Ig-alpha.A novel germ-line JK transcript starting immediately upstream of JK1Activated Ras signals developmental progression of recombinase-activating gene (RAG)-deficient pro-B lymphocytes.Progenitor tumours from Emu-bcl-2-myc transgenic mice have lymphomyeloid differentiation potential and reveal developmental differences in cell survivalComplete structure and organization of immunoglobulin heavy chain constant region genes in a phylogenetically primitive vertebrate.Immunoglobulin heavy chain expression shapes the B cell receptor repertoire in human B cell developmentVirus-transformed pre-B cells show ordered activation but not inactivation of immunoglobulin gene rearrangement and transcription.Inhibition of immunoglobulin gene rearrangement by the expression of a lambda 2 transgene.Molecular characterization of transgene-induced immunodeficiency in B-less mice using a novel quantitative limiting dilution polymerase chain reaction method.Immunoglobulin beta signaling regulates locus accessibility for ordered immunoglobulin gene rearrangements.Ras mediates effector pathways responsible for pre-B cell survival, which is essential for the developmental progression to the late pre-B cell stage.Regulation of B lymphocyte development by the truncated immunoglobulin heavy chain protein Dmu.Wild-type V(D)J recombination in scid pre-B cellsA novel gene product associated with mu chains in immature B cells.From gene amplification to V(D)J recombination and back: a personal account of my early years in B cell biologyStochastic rearrangement of immunoglobulin variable-region genes in chicken B-cell development.Induction of Ig light chain gene rearrangement in heavy chain-deficient B cells by activated Ras.Pre-B cell receptor expression is necessary for thymic stromal lymphopoietin responsiveness in the bone marrow but not in the liver environment.Effects of acute and chronic inflammation on B-cell development and differentiation.Normal pre-B cells express a receptor complex of mu heavy chains and surrogate light-chain proteins.Antigen-stimulated dissociation of BCR mIg from Ig-alpha/Ig-beta: implications for receptor desensitization.The IgM antigen receptor of B lymphocytes is associated with prohibitin and a prohibitin-related protein.Inducible site-directed recombination in mouse embryonic stem cellsPCR-based cDNA library construction: general cDNA libraries at the level of a few cells.Two new proteins preferentially associated with membrane immunoglobulin D.A surrogate 15 kDa JC kappa protein is expressed in combination with mu heavy chain by human B cell precursors.Promoter, enhancer and silencer elements regulate rearrangement of an immunoglobulin transgene.
P2860
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P2860
Activation of V kappa gene rearrangement in pre-B cells follows the expression of membrane-bound immunoglobulin heavy chains.
description
1987 nî lūn-bûn
@nan
1987年の論文
@ja
1987年論文
@yue
1987年論文
@zh-hant
1987年論文
@zh-hk
1987年論文
@zh-mo
1987年論文
@zh-tw
1987年论文
@wuu
1987年论文
@zh
1987年论文
@zh-cn
name
Activation of V kappa gene rea ...... d immunoglobulin heavy chains.
@en
type
label
Activation of V kappa gene rea ...... d immunoglobulin heavy chains.
@en
prefLabel
Activation of V kappa gene rea ...... d immunoglobulin heavy chains.
@en
P2093
P2860
P1433
P1476
Activation of V kappa gene rea ...... d immunoglobulin heavy chains.
@en
P2093
P2860
P304
P407
P577
1987-11-01T00:00:00Z